Gene | Average Ct | Average ᐃCt | 2-ᐃCt | Fold Change | Fold Regulation | |||||
---|---|---|---|---|---|---|---|---|---|---|
CLL | Control | CLL | Control | CLL | Control | CLL/ Control | 95% CI | CLL/ Control | ||
26.57 | 25.28 | 7.72 | 7.54 | 0.004695 | 0.005368 | 0.87 | 0.78-0.96 | 0.072729 | -1.14 | |
27.85 | 27.91 | 9.01 | 10.17 | 0.001936 | 0.000869 | 2.23 | 1.67-2.79 | <0.001 | 2.23 | |
29.00 | 29.41 | 10.17 | 11.67 | 0.000871 | 0.000307 | 2.83 | 2.23-3.43 | <0.001 | 2.83 | |
25.61 | 25.87 | 6.78 | 8.13 | 0.009116 | 0.003578 | 2.55 | 2.15-2.95 | <0.001 | 2.55 | |
27.35 | 27.58 | 8.52 | 9.84 | 0.002723 | 0.001091 | 2.50 | 2.06-2.94 | <0.001 | 2.50 | |
26.92 | 27.96 | 8.09 | 10.22 | 0.003672 | 0.000839 | 4.38 | 3.20-5.56 | <0.001 | 4.38 | |
27.59 | 26.82 | 8.75 | 9.08 | 0.002315 | 0.001852 | 1.25 | 0.97-1.53 | 0.066 | 1.25 | |
30.50 | 32.77 | 11.67 | 15.02 | 0.000307 | 0.000030 | 10.22 | 7.14-13.3 | <0.001 | 10.22 | |
31.37 | 31.58 | 12.54 | 13.83 | 0.000168 | 0.000068 | 2.45 | 1.98-2.92 | <0.001 | 2.45 | |
29.45 | 30.42 | 10.62 | 12.68 | 0.000638 | 0.000152 | 4.18 | 3.02-5.34 | <0.001 | 4.18 | |
31.44 | 30.88 | 12.60 | 13.14 | 0.000161 | 0.000111 | 1.45 | 1.04-1.86 | 0.012741 | 1.45 | |
28.88 | 27.09 | 10.05 | 9.34 | 0.000944 | 0.001541 | 0.61 | 0.53-0.69 | <0.001 | -1.63 | |
31.94 | 31.14 | 13.10 | 13.39 | 0.000114 | 0.000093 | 1.22 | 0.90-1.54 | 0.121 | 1.22 | |
23.34 | 21.85 | 4.51 | 4.11 | 0.043950 | 0.057965 | 0.76 | 0.66-0.86 | <0.001 | -1.32 | |
25.77 | 25.60 | 6.93 | 7.86 | 0.008184 | 0.004312 | 1.90 | 1.56-2.24 | <0.001 | 1.90 | |
27.43 | 28.00 | 8.60 | 10.26 | 0.002577 | 0.000818 | 3.15 | 2.32-3.998 | <0.001 | 3.15 | |
25.75 | 26.36 | 6.92 | 8.62 | 0.008266 | 0.002545 | 3.25 | 2.64-3.86 | <0.001 | 3.25 | |
25.53 | 24.05 | 6.50 | 6.31 | 0.011036 | 0.012615 | 0.87 | 0.78-0.96 | 0.062542 | -1.14 | |
26.51 | 27.04 | 7.67 | 9.29 | 0.004894 | 0.001595 | 3.07 | 2.40-3.74 | <0.001 | 3.07 | |
25.76 | 26.32 | 6.92 | 8.58 | 0.008229 | 0.002619 | 3.14 | 2.47-3.81 | <0.001 | 3.14 | |
32.50 | 30.53 | 13.67 | 12.79 | 0.000077 | 0.000141 | 0.54 | 0.37-0.71 | 0.006057 | -1.84 | |
25.94 | 27.94 | 7.11 | 10.20 | 0.007231 | 0.000850 | 8.5' | 5.46-11.56 | <0.001 | 8.51 |
Sex-Age | Prognosis | Rai Stage | Binet Stage | FISH Results | (WBC 109/L) | Hb (g/dL) | Platelet (109/L) | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
del(13q) | del(17p) | +12 | Normal Non-del(13q), del(17p), +12. | ||||||||
1 | F-75 | bad | 1 | B | [–] | [+] | [–] | [–] | 12.6 | 12.7 | 166.0 |
2 | M-71 | good | 0 | A | [–] | [–] | [–] | [+] | 23.0 | 12.0 | 203.0 |
3 | M-57 | good | 0 | A | [–] | [–] | [–] | [+] | 24.8 | 15.1 | 262.0 |
4 | M-56 | good | 3 | A | [–] | [–] | [–] | [+] | 71.4 | 13.2 | 49.0 |
5 | F-59 | bad | 2 | B | [–] | [+] | [–] | [–] | 7.9 | 10.9 | 284.0 |
6 | F-74 | bad | 2 | B | [–] | [+] | [–] | [–] | 108.6 | 10.3 | 190.0 |
7 | F-63 | bad | 2 | A | [–] | [+] | [–] | [–] | 35.4 | 13.4 | 185.0 |
8 | M-80 | bad | 2 | A | [–] | [+] | [–] | [–] | 3.6 | 12.9 | 104.0 |
9 | F-62 | bad | 0 | A | [–] | [–] | [+] | [–] | 190.2 | 12.0 | 192.0 |
10 | M-67 | bad | 2 | A | [–] | [–] | [+] | [–] | 142.6 | 11.6 | 81.0 |
11 | F-65 | bad | 0 | A | [–] | [–] | [+] | [–] | 5.2 | 12.1 | 144.0 |
12 | F-74 | bad | 2 | A | [–] | [–] | [+] | [–] | 179.7 | 11.9 | 321.0 |
13 | F-86 | bad | 3 | A | [–] | [–] | [+] | [–] | 213.0 | 8.6 | 113.0 |
14 | M-60 | good | 3 | A | [–] | [–] | [–] | [+] | 51.7 | 9.4 | 137.0 |
15 | M-46 | good | 2 | A | [–] | [–] | [–] | [+] | 15.0 | 14.4 | 184.0 |
16 | M-54 | good | 0 | A | [–] | [–] | [–] | [+] | 41.9 | 13.8 | 352.0 |
17 | F-61 | good | 1 | A | [–] | [–] | [–] | [+] | 11.8 | 12.1 | 148.0 |
18 | F-67 | good | 0 | A | [–] | [–] | [–] | [+] | 195.3 | 10.8 | 188.0 |
19 | F-53 | good | 2 | B | [–] | [–] | [–] | [+] | 39.8 | 11.4 | 135.0 |
20 | M-67 | good | 0 | A | [+] | [–] | [–] | [–] | 74.6 | 12.4 | 183.0 |
21 | M-62 | good | 2 | A | [+] | [–] | [–] | [–] | 121.4 | 14.5 | 294.0 |
22 | M-68 | good | 0 | A | [+] | [–] | [–] | [–] | 37.7 | 13.9 | 197.0 |
23 | F-46 | good | 1 | A | [+] | [–] | [–] | [–] | 59.4 | 12.3 | 91.0 |
24 | M-58 | good | 2 | B | [+] | [–] | [–] | [–] | 201.4 | 11.1 | 101.0 |
25 | M-66 | good | 0 | A | [+] | [–] | [–] | [–] | 43.9 | 12.3 | 88.0 |
26 | M-61 | good | 4 | C | [+] | [–] | [–] | [–] | 110.0 | 13.9 | 39.0 |
27 | M-51 | good | 2 | A | [+] | [–] | [–] | [–] | 98.5 | 14.3 | 250.0 |
28 | F-78 | good | 3 | B | [+] | [–] | [–] | [–] | 13.7 | 11.0 | 324.0 |
29 | F-63 | good | 0 | A | [+] | [–] | [–] | [–] | 113.3 | 11.5 | 178.0 |
30 | M-64 | good | 0 | A | [+] | [–] | [–] | [–] | 432.0 | 15.3 | 206.0 |