Molecular functions |
GO:0005212 |
structural constituent of eye lens |
2.806E-8 |
4 |
25 |
GO:0032405 |
MutLalpha complex binding |
6.840E-8 |
3 |
7 |
GO:0032404 |
mismatch repair complex binding |
3.214E-7 |
3 |
11 |
GO:0032407 |
MutSalpha complex binding |
3.412E-5 |
2 |
7 |
GO:0044877 |
protein-containing complex binding |
2.123E-4 |
9 |
1726 |
GO:0003950 |
NAD+ ADP-ribosyltransferase activity |
6.938E-4 |
2 |
30 |
GO:0047485 |
protein N-terminus binding |
7.323E-4 |
3 |
137 |
GO:0050699 |
WW domain binding |
8.919E-4 |
2 |
34 |
GO:0004108 |
citrate (Si)-synthase activity |
1.304E-3 |
1 |
1 |
GO:0160011 |
NAD-dependent protein decrotonylase activity |
1.304E-3 |
1 |
1 |
GO:0160012 |
NAD-dependent histone decrotonylase activity |
1.304E-3 |
1 |
1 |
GO:0036440 |
citrate synthase activity |
1.304E-3 |
1 |
1 |
GO:0016763 |
pentosyltransferase activity |
2.491E-3 |
2 |
57 |
GO:0106231 |
protein-propionyllysine depropionylase activity |
2.603E-3 |
1 |
2 |
GO:0032129 |
histone deacetylase activity (H3-K9 specific) |
2.603E-3 |
1 |
2 |
Biological processes |
GO:0071479 |
cellular response to ionising radiation |
1.415E-11 |
7 |
90 |
GO:0042770 |
signal transduction in response to DNA damage |
8.815E-11 |
8 |
200 |
GO:0010212 |
response to ionising radiation |
9.545E-11 |
8 |
202 |
GO:0072331 |
signal transduction by p53 class mediator |
9.545E-11 |
8 |
202 |
GO:0071480 |
cellular response to gamma radiation |
5.615E-10 |
5 |
34 |
GO:0030330 |
DNA damage response, signal transduction by p53 class mediator |
7.424E-10 |
6 |
83 |
GO:0043516 |
regulation of DNA damage response, signal transduction by p53 class mediator |
2.173E-9 |
5 |
44 |
GO:0043517 |
positive regulation of DNA damage response, signal transduction by p53 class mediator |
4.584E-9 |
4 |
17 |
GO:0097190 |
apoptotic signaling pathway |
7.241E-9 |
10 |
715 |
GO:0071478 |
cellular response to radiation |
8.951E-9 |
7 |
225 |
GO:0010332 |
response to gamma radiation |
4.104E-8 |
5 |
78 |
GO:0009314 |
response to radiation |
5.117E-8 |
9 |
646 |
GO:0045786 |
negative regulation of cell cycle |
8.888E-8 |
8 |
483 |
GO:1901798 |
positive regulation of signal transduction by p53 class mediator |
9.931E-8 |
4 |
35 |
GO:0097193 |
intrinsic apoptotic signalling pathway |
2.361E-7 |
7 |
363 |
Cellular components |
GO:0061773 |
eNoSc complex |
4.112E-6 |
2 |
3 |
GO:0140552 |
TEAD-YAP complex |
4.112E-6 |
2 |
3 |
GO:0033553 |
rDNA heterochromatin |
8.218E-6 |
2 |
4 |
GO:0000781 |
chromosome, telomeric region |
4.993E-5 |
4 |
173 |
GO:0005677 |
chromatin silencing complex |
1.237E-4 |
2 |
14 |
GO:0140513 |
nuclear protein-containing complex |
1.424E-4 |
8 |
1386 |
GO:0016605 |
PML body |
4.055E-4 |
3 |
122 |
GO:0098687 |
chromosomal region |
1.439E-3 |
4 |
419 |
GO:0070310 |
ATR-ATRIP complex |
2.389E-3 |
1 |
2 |
GO:0032301 |
MutSalpha complex |
2.389E-3 |
1 |
2 |
GO:0034686 |
integrin alphav-beta8 complex |
2.389E-3 |
1 |
2 |
GO:0032302 |
MutSbeta complex |
2.389E-3 |
1 |
2 |
GO:0099126 |
transforming growth factor beta complex |
3.582E-3 |
1 |
3 |
GO:1902636 |
kinociliary basal body |
3.582E-3 |
1 |
3 |
GO:0005657 |
replication fork |
3.703E-3 |
2 |
76 |
Molecular pathways |
M9703 |
role of BRCA1, BRCA2 and ATR in Cancer Susceptibility |
3.010E-8 |
4 |
22 |
M39490 |
DNA IR-damage and cellular response via ATR |
1.245E-7 |
5 |
81 |
M39598 |
DNA IR-double strand breaks and cellular response via ATM |
1.358E-6 |
4 |
55 |
M648 |
cell Cycle: G1/S Check Point |
1.012E-5 |
3 |
28 |
137959 |
BARD1 signalling events |
1.128E-5 |
3 |
29 |
M258 |
BARD1 signalling events |
1.128E-5 |
3 |
29 |
1270252 |
molecules associated with elastic fibres |
1.384E-5 |
3 |
31 |
1309108 |
HDR through Single Strand Annealing (SSA) |
2.580E-5 |
3 |
38 |
1309104 |
presynaptic phase of homologous DNA pairing and strand exchange |
3.016E-5 |
3 |
40 |
M40049 |
DNA repair pathways, full network |
3.166E-5 |
4 |
121 |
1309097 |
sensing of DNA Double Strand Breaks |
3.389E-5 |
2 |
6 |
1270251 |
elastic fibre formation |
3.497E-5 |
3 |
42 |
1309103 |
homologous DNA Pairing and Strand Exchange |
3.756E-5 |
3 |
43 |
M39628 |
integrated cancer pathway |
4.310E-5 |
3 |
45 |
M39518 |
ATM signalling in development and disease |
4.606E-5 |
3 |
46 |