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Figure 1.

Stray dog in Iran. Photograph taken by Reyhaneh Rasizadeh, in rural areas of East Azerbaijan province, in March 2023
Stray dog in Iran. Photograph taken by Reyhaneh Rasizadeh, in rural areas of East Azerbaijan province, in March 2023

Figure 2.

Animal reservoirs of rabies virus. Dogs constitute the main source of infection for human rabies worldwide, thus playing a key role in the eradication of dog-mediated human rabies
Animal reservoirs of rabies virus. Dogs constitute the main source of infection for human rabies worldwide, thus playing a key role in the eradication of dog-mediated human rabies

The different approaches used in developing countries and low-income countries

Developed countries Benefited largely from rabies globalization
Applying different vaccination methods; such as door-to-door vaccination, oral vaccination, capture vaccination, and combination of these methods
Taking preemptive measures due to lower costs
Maintaining the preventive measures and vaccination in rabies free areas
Canine vaccinations in combination with post-exposure prophylaxis (PEP)
Close cooperation between public health and animal health
High rabies education
Low-income countries Low illness awareness
Free ranging dog populations
Lack of international collaboration
Limited accessible resources for dog owners
Lack of effective communication between the veterinary and the human health sectors
Rarely enforced canine vaccinations
Approaching post-exposure prophylaxis (PEP) only
Old-fashioned preemptive control methods such as mass culling of community dogs
Creating an ecological vacuum and attracting more dogs into the area due to outdated methods
PEP is the only form in which a country tries to control rabies
Much more severe economic burden of rabies; Direct medical costs from post-exposure prophylaxis (PEP), costs of controlling rabies among dogs, livestock losses, and surveillance costs
Lack of official livestock vaccination in the Veterinary Services’ control programs
Prevention of outbreaks is the primary goal in the fight against rabies due to lack of resources in some areas
Out-of-date laws
Poor veterinary and human health infrastructure
Lack of vaccination programs for animals playing a role in rabies cycle
Mismanagement of funds
No close cooperation between public health and animal health
Low rabies education
High importance of rabies owing to the fact that animal husbandry is a main means of livelihood
Implementing development impact bonds could be an effective way to deal with long term financial commitment in these countries
Developing region-specific networks such as MERACON
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Temas de la revista:
Life Sciences, Molecular Biology, Microbiology and Virology, Medicine, Basic Medical Science, Immunology