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FIGURE 1.

Receiver operating characteristic (ROC) curve of the Child Behavior Checklist-Bipolar Profile T-scores in subjects from the total sample with and without Bipolar I disorder (n = 661)
Receiver operating characteristic (ROC) curve of the Child Behavior Checklist-Bipolar Profile T-scores in subjects from the total sample with and without Bipolar I disorder (n = 661)

Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and percent correctly classified in the use of the Child Behavior Checklist-Bipolar (BP) profile t-scores to identify youth with BP-I disorder in the total sample from all four studies (n = 661)

CBCL-BP profile Cut-pointSensitivity (%)Specificity (%)PPV (%)NPV (%)Correctly classified (%)
≥ 1659563399869
≥ 1808977499779
≥ 195*8087619586
≥ 2106194729188
≥ 2253997798786
≥ 2401599868383

Sensitivity, specificity and percent correctly classified using the Child Behavior Checklist-Bipolar (BP) profile with ≥ 180 to identify youth with BP-I disorder in each study

StudySensitivity (%)Specificity (%)Correctly classified (%)
Boys ADHD study (n = 251)857474
Girls ADHD study (n = 220)897475
BP disorder controlled study (n = 146)899391
BP disorder family study (n = 44)91n/aa91

Demographic characteristics of those with and without BP-I disorder from the individual studies and all studies combined

Boys ADHD studyGirls ADHD studyBP disorder controlled studyBP disorder family studyAll studies combined
No BP disorderBP disorderNo BP disorderBP disorderNo BP disorderBP disorderNo BP disorderBP disorderNo BP disorderBP disorder
n = 238n = 13n = 211n = 9n = 82n = 64n = n/an = 44n = 531n = 130Test statisticp-value
Mean ± SDMean ± SDMean ± SDMean ± SDMean ± SDMean ± SDMean ± SDMean ± SDMean ± SDMean ± SD
Age11.1 ± 3.310.3 ± 3.311.7 ± 3.211.0 ± 3.313.5 ± 2.113.7 ± 2.4n/a9.2 ± 3.411.7 ± 3.211.7 ± 3.6t659 = 0.080.94
Socioeconomic statusa1.7 ± 0.92.1 ± 1.01.8 ± 0.91.8 ± 0.71.6 ± 1.01.9 ± 1.2n/a1.8 ± 1.01.7 ± 0.91.8 ± 1.1z = -1.290.20
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Medicine, Basic Medical Science, other