Further evidence of the Diagnostic Utility of the Child Behavior Checklist for identifying pediatric Bipolar I Disorder

Receiver operating characteristic (ROC) curve of the Child Behavior Checklist-Bipolar Profile T-scores in subjects from the total sample with and without Bipolar I disorder (n = 661)

Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and percent correctly classified in the use of the Child Behavior Checklist-Bipolar (BP) profile t-scores to identify youth with BP-I disorder in the total sample from all four studies (n = 661)

CBCL-BP profile Cut-point	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Correctly classified (%)
≥ 165	95	63	39	98	69
≥ 180	89	77	49	97	79
≥ 195^*	80	87	61	95	86
≥ 210	61	94	72	91	88
≥ 225	39	97	79	87	86
≥ 240	15	99	86	83	83

Sensitivity, specificity and percent correctly classified using the Child Behavior Checklist-Bipolar (BP) profile with ≥ 180 to identify youth with BP-I disorder in each study

Study	Sensitivity (%)	Specificity (%)	Correctly classified (%)
Boys ADHD study (n = 251)	85	74	74
Girls ADHD study (n = 220)	89	74	75
BP disorder controlled study (n = 146)	89	93	91
BP disorder family study (n = 44)	91	n/a^a	91

Demographic characteristics of those with and without BP-I disorder from the individual studies and all studies combined

	Boys ADHD study		Girls ADHD study		BP disorder controlled study		BP disorder family study		All studies combined
	No BP disorder	BP disorder	No BP disorder	BP disorder	No BP disorder	BP disorder	No BP disorder	BP disorder	No BP disorder	BP disorder
	n = 238	n = 13	n = 211	n = 9	n = 82	n = 64	n = n/a	n = 44	n = 531	n = 130	Test statistic	p-value
	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD
Age	11.1 ± 3.3	10.3 ± 3.3	11.7 ± 3.2	11.0 ± 3.3	13.5 ± 2.1	13.7 ± 2.4	n/a	9.2 ± 3.4	11.7 ± 3.2	11.7 ± 3.6	t₆₅₉ = 0.08	0.94
Socioeconomic status^a	1.7 ± 0.9	2.1 ± 1.0	1.8 ± 0.9	1.8 ± 0.7	1.6 ± 1.0	1.9 ± 1.2	n/a	1.8 ± 1.0	1.7 ± 0.9	1.8 ± 1.1	z = -1.29	0.20

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Further evidence of the Diagnostic Utility of the Child Behavior Checklist for identifying pediatric Bipolar I Disorder

Online veröffentlicht: 06. Juni 2019

Seitenbereich: 1 - 8

DOI: https://doi.org/10.21307/sjcapp-2019-006

SchlüsselwörterBipolar disorder, behavior, child and adolescent psychiatry

© 2019 Amy Yule et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

FIGURE 1.

Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and percent correctly classified in the use of the Child Behavior Checklist-Bipolar (BP) profile t-scores to identify youth with BP-I disorder in the total sample from all four studies (n = 661)

Sensitivity, specificity and percent correctly classified using the Child Behavior Checklist-Bipolar (BP) profile with ≥ 180 to identify youth with BP-I disorder in each study

Demographic characteristics of those with and without BP-I disorder from the individual studies and all studies combined

Schlüsselwörter
Bipolar disorder, behavior, child and adolescent psychiatry