[1. Cohen JC, Horton JD, Hobbs HH. Human fatty liver disease: old questions and new insights. Science. 2011;332(6037):1519-23.10.1126/science.1204265]Search in Google Scholar
[2. Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, Strowig T, et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature. 2012;482(7384):179-85.10.1038/nature10809]Search in Google Scholar
[3. Choi S, Diehl AM. Role of inflammation in nonalcoholic steatohepatitis. Current opinion in gastroenterology. 2005;21(6):702-7.10.1097/01.mog.0000182863.96421.47]Search in Google Scholar
[4. Mouralidarane A, Soeda J, Visconti-Pugmire C, Samuelsson AM, Pombo J, Maragkoudaki X, et al. Maternal obesity programs offspring nonalcoholic fatty liver disease by innate immune dysfunction in mice. Hepatology. 2013;58(1):128-38.10.1002/hep.26248]Search in Google Scholar
[5. Li Z, Soloski MJ, Diehl AM. Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease. Hepatology. 2005;42(4):880-5.10.1002/hep.20826]Search in Google Scholar
[6. Grarup N, Sandholt CH, Hansen T, Pedersen O. Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond. Diabetologia. 2014;57(8):1528-41.10.1007/s00125-014-3270-4]Search in Google Scholar
[7. Lin YC, Chang PF, Chang MH, Ni YH. Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals. Am J Clin Nutr. 2014;99(4):869-74.10.3945/ajcn.113.079749]Search in Google Scholar
[8. Postic C, Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest. 2008;118(3):829-38.10.1172/JCI34275]Search in Google Scholar
[9. Ferre P, Foufelle F. Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c. Diabetes, obesity & metabolism. 2010;12 Suppl 2:83-92.10.1111/j.1463-1326.2010.01275.x]Search in Google Scholar
[10. Negrin KA, Roth Flach RJ, DiStefano MT, Matevossian A, Friedline RH, Jung D, et al. IL-1 signaling in obesity-induced hepatic lipogenesis and steatosis. PLoS One. 2014;9(9):e107265.10.1371/journal.pone.0107265]Search in Google Scholar
[11. Milovanovic M, Volarevic V, Radosavljevic G, Jovanovic I, Pejnovic N, Arsenijevic N, et al. IL-33/ST2 axis in inflammation and immunopathology. Immunol Res. 2012;52(1-2):89-99.10.1007/s12026-012-8283-9]Search in Google Scholar
[12. Miller AM, Asquith DL, Hueber AJ, Anderson LA, Holmes WM, McKenzie AN, et al. Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circ Res. 2010;107(5):650-8.10.1161/CIRCRESAHA.110.218867]Search in Google Scholar
[13. Marvie P, Lisbonne M, L'Helgoualc'h A, Rauch M, Turlin B, Preisser L, et al. Interleukin-33 overexpression is associated with liver fibrosis in mice and humans. J Cell Mol Med. 2010;14(6b):1726-39.10.1111/j.1582-4934.2009.00801.x]Search in Google Scholar
[14. McHedlidze T, Waldner M, Zopf S, Walker J, Rankin AL, Schuchmann M, et al. Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis. Immunity. 2013;39(2):357-71.10.1016/j.immuni.2013.07.018]Search in Google Scholar
[15. Townsend MJ, Fallon PG, Matthews DJ, Jolin HE, McKenzie AN. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J Exp Med. 2000;191(6):1069-76.10.1084/jem.191.6.1069]Search in Google Scholar
[16. Junqueira LC, Bignolas G, Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J. 1979;11(4):447-55.10.1007/BF01002772]Search in Google Scholar
[17. Hadi AM, Mouchaers KT, Schalij I, Grunberg K, Meijer GA, Vonk-Noordegraaf A, et al. Rapid quantification of myocardial fibrosis: A new macro-based automated analysis. Anal Cell Pathol (Amst). 2010;33(5):257-69.10.1155/2010/858356]Search in Google Scholar
[18. Deutsch MJ, Schriever SC, Roscher AA, Ensenauer R. Digital image analysis approach for lipid droplet size quantitation of Oil Red O-stained cultured cells. Anal Biochem. 2014;445:87-9.10.1016/j.ab.2013.10.001]Search in Google Scholar
[19. Juluri R, Vuppalanchi R, Olson J, Unalp A, Van Natta ML, Cummings OW, et al. Generalizability of the non-alcoholic steatohepatitis Clinical Research Network histologic scoring system for nonalcoholic fatty liver disease. J Clin Gastroenterol. 2011;45(1):55-8.10.1097/MCG.0b013e3181dd1348]Search in Google Scholar
[20. Volarevic V, Mitrovic M, Milovanovic M, Zelen I, Nikolic I, Mitrovic S, et al. Protective role of IL-33/ST2 axis in Con A-induced hepatitis. J Hepatol. 2012;56(1):26-33.10.1016/j.jhep.2011.03.022]Search in Google Scholar
[21. Foster B, Prussin C, Liu F, Whitmire JK, Whitton JL. Detection of intracellular cytokines by flow cytometry. Curr Protoc Immunol. 2007;Chapter 6:Unit 6.24.10.1002/0471142735.im0624s78]Search in Google Scholar
[22. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402-8.10.1006/meth.2001.1262]Search in Google Scholar
[23. Montgomery MK, Hallahan NL, Brown SH, Liu M, Mitchell TW, Cooney GJ, et al. Mouse strain-dependent variation in obesity and glucose homeostasis in response to high-fat feeding. Diabetologia. 2013;56(5):1129-39.10.1007/s00125-013-2846-8]Search in Google Scholar
[24. Pantic JM, Pejnovic NN, Radosavljevic GD, Jovanovic I.P, Djukic ALJ, Arsenijevic NN, Lukic ML. Lack of ST2 enhances high - fat diet -induced visceral adiposity and inflammation in BALB/c mice [Delecija gena za ST2 promoviše gojaznost i inflamaciju u visceralnom adipoznom tkivu BALB/c miševa na dijeti sa visokim sadržajem masti]. Serb J Exp Clin Res 2013; 14(4): 155 -160.10.5937/sjecr14-5243]Search in Google Scholar
[25. Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest. 2005;115(5):1343-51.10.1172/JCI23621]Search in Google Scholar
[26. Langin D. Adipose tissue lipolysis as a metabolic pathway to define pharmacological strategies against obesity and the metabolic syndrome. Pharmacol Res. 2006;53(6):482-91.10.1016/j.phrs.2006.03.009]Search in Google Scholar
[27. McKenna LA, Jordan F, Brown EA, Huda SS, Mackay VA, Miller AM, et al. The role of interleukin-33 and its receptor ST2 in human pregnancy. Archives of Disease in Childhood - Fetal and Neonatal Edition. 2011;96(Suppl 1):Fa98.10.1136/adc.2011.300163.5]Search in Google Scholar
[28. Su X, Abumrad NA. Cellular fatty acid uptake: a pathway under construction. Trends Endocrinol Metab. 2009;20(2):72-7.10.1016/j.tem.2008.11.001]Search in Google Scholar
[29. Grefhorst A, Parks EJ. Reduced insulin-mediated inhibition of VLDL secretion upon pharmacological activation of the liver X receptor in mice. J Lipid Res. 2009;50(7):1374-83.10.1194/jlr.M800505-JLR200]Search in Google Scholar
[30. Beaven SW, Matveyenko A, Wroblewski K, Chao L, Wilpitz D, Hsu TW, et al. Reciprocal regulation of hepatic and adipose lipogenesis by liver X receptors in obesity and insulin resistance. Cell metabolism. 2013;18(1):106-17.10.1016/j.cmet.2013.04.021]Search in Google Scholar
[31. Moran-Salvador E, Lopez-Parra M, Garcia-Alonso V, Titos E, Martinez-Clemente M, Gonzalez-Periz A, et al. Role for PPARgamma in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts. FASEB J. 2011;25(8):2538-50.10.1096/fj.10-173716]Search in Google Scholar
[32. Tang Y, Bian Z, Zhao L, Liu Y, Liang S, Wang Q, et al. Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease. Clin Exp Immunol. 2011;166(2):281-90.10.1111/j.1365-2249.2011.04471.x]Search in Google Scholar
[33. Tan Z, Qian X, Jiang R, Liu Q, Wang Y, Chen C, et al. IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation. J Immunol. 2013;191(4):1835-44.10.4049/jimmunol.1203013]Search in Google Scholar
[34. Lin SL, Castano AP, Nowlin BT, Lupher ML, Jr., Duffield JS. Bone marrow Ly6Chigh monocytes are selectively recruited to injured kidney and differentiate into functionally distinct populations. J Immunol. 2009;183(10):6733-43.10.4049/jimmunol.0901473]Search in Google Scholar
[35. Karlmark KR, Weiskirchen R, Zimmermann HW, Gassler N, Ginhoux F, Weber C, et al. Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis. Hepatology. 2009;50(1):261-74.10.1002/hep.22950]Search in Google Scholar
[36. Tacke F. Functional role of intrahepatic monocyte subsets for the progression of liver inflammation and liver fibrosis in vivo. Fibrogenesis & tissue repair. 2012;5(Suppl 1 Proceedings of Fibroproliferative disorders: from biochemical analysis to targeted therapies-Petro E Petrides and David Brenner):S27.10.1186/1755-1536-5-S1-S27]Search in Google Scholar