Screening of 17α-ethynylestradiol and non-steroidal anti-inflammatory pharmaceuticals accumulation in Mytilus edulis trossulus (Gould, 1890) collected from the Gulf of Gdańsk

Álvarez-Muñoz, D., Rodríguez-Mozaz, S., Maulvault, A.L., Tediosi, A., Fernández-Tejedor, M.V. et al. (2015). Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe. Environ. Res. 143: 56-64. DOI: 10.1016/j. envres.2015.09.018. Álvarez-Muñoz,D.Rodríguez-Mozaz,S.Maulvault,A.L.Tediosi,A.Fernández-Tejedor,M.V.2015Occurrence of pharmaceuticals and endocrine disrupting compounds in macroalgaes, bivalves, and fish from coastal areas in Europe.Environ. Res143566410.1016/j. envres.2015.09.018.Open DOISearch in Google Scholar

Arnot, J.A. & Gobas, S. (2006). A review of bioconcentration factor (BCF) and bioaccumulation factor (BAF) assessments for organic chemicals in aquatic organisms. Environ. Reviews. 14: 257-297. DOI: 10.1139/a06-005. Arnot,J.A.Gobas,S.2006A review of bioconcentration factor (BCF) and bioaccumulation factor (BAF) assessments for organic chemicals in aquatic organisms.Environ. Reviews1425729710.1139/a06-005.Open DOISearch in Google Scholar

Binelli, A., Della Torre, C., Magni, S. & Parolini, M. (2014). Does zebra mussel (Dreissena polymorpha) represent the freshwater counterpart of Mytilus in ecotoxicological studies? A critical review. Environ. Pollut. 196C: 386-403. DOI: 10.1016/j.envpol.2014.10.023. Binelli,A.Della Torre,C.Magni,S.Parolini,M.2014Does zebra mussel (Dreissena polymorpha) represent the freshwater counterpart of Mytilus in ecotoxicological studies? A critical review.Environ. Pollut.196C38640310.1016/j.envpol.2014.10.023.Open DOISearch in Google Scholar

Binelli, A., Magni, S., Soave, C., Marazzi, F., Zuccato, E. et al. (2014). The biofiltration process by the bivalve D. polymorpha for the removal of some pharmaceuticals and drugs of abuse from civil wastewaters. Ecol. Eng. 71: 710-721. DOI: 10.1016/j.ecoleng.2014.08.004. Binelli,A.Magni,S.Soave,C.Marazzi,F.Zuccato,E.2014The biofiltration process by the bivalve D. polymorpha for the removal of some pharmaceuticals and drugs of abuse from civil wastewaters.Ecol. Eng.7171072110.1016/j.ecoleng.2014.08.004.Open DOISearch in Google Scholar

Borecka, M., Siedlewicz, G., Haliński, Ł.P., Sikora, K., Pazdro, K. et al. (2015). Contamination of the southern Baltic Sea waters by the residues of selected pharmaceuticals: Method development and field studies. Mar. Pollut. Bull. 94: 62-71. DOI: 10.1016/j.marpolbul.2015.03.008. Borecka,M.Siedlewicz,G.Haliński,Ł.P.,Sikora,K.Pazdro,K.2015Contamination of the southern Baltic Sea waters by the residues of selected pharmaceuticals: Method development and field studies.Mar. Pollut. Bull94627110.1016/j.marpolbul.2015.03.008.Open DOISearch in Google Scholar

Caban, M., Lis, E., Kumirska, J. & Stepnowski, P. (2015). Determination of pharmaceutical residues in drinking water in Poland using a new SPE-GC-MS(SIM) method based on Speedisk extraction disks and DIMETRIS derivatization. Sci. Total Environ. 538: 402-411. DOI: 10.1016/j.scitotenv.2015.08.076. Caban,M.Lis,E.Kumirska,J.Stepnowski,P.2015Determination of pharmaceutical residues in drinking water in Poland using a new SPE-GC-MS(SIM) method based on Speedisk extraction disks and DIMETRISderivatization.Sci. Total Environ.53840241110.1016/j.scitotenv.2015.08.076.Open DOISearch in Google Scholar

Caban, M., Mioduszewska, K., Łukaszewicz, P., Migowska, N., Stepnowski, P. et al. (2014). A new silylating reagent - dimethyl(3,3,3-trifluoropropyl)silyldiethylamine - for the derivatisation of non-steroidal anti-inflammatory drugs prior to gas chromatography-mass spectrometry analysis. J. Chromatogr. A 1346: 107-116. DOI: 10.1016/j. chroma.2014.04.054. Caban,M.Mioduszewska,K.Łukaszewicz,P.,Migowska,N.Stepnowski,P.2014A new silylating reagent - dimethyl(3,3,3-trifluoropropyl)silyldiethylamine - for the derivatisation of non-steroidal anti-inflammatory drugs prior to gas chromatography-mass spectrometry analysis.J. Chromatogr. A134610711610.1016/j. chroma.2014.04.054.Open DOISearch in Google Scholar

Camacho-Muñoz, D., Martín, J., Santos, J.L., Aparicio, I. & Alonso, E. (2010). Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain). J. Hazard. Mater. 183: 602-608. DOI: 10.1016/j.jhazmat.2010.07.067. Camacho-Muñoz,D.Martín,J.,Santos,J.L.Aparicio,I.Alonso,E.2010Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain).J. Hazard. Mater18360260810.1016/j.jhazmat.2010.07.067.Open DOISearch in Google Scholar

Cleuvers, M. (2003). Aquatic ecotoxicity of pharmaceuticals including the assessment of combination Effects. Toxicol. Lett. 142: 185-194. DOI: 10.1016/S0378-4274(03)00068-7. Cleuvers,M.2003Aquatic ecotoxicity of pharmaceuticals including the assessment of combination Effects.Toxicol. Lett14218519410.1016/S0378-4274(03)00068-7.Open DOISearch in Google Scholar

Cubero-Leon, E., Ciocan, C.M., Hill, E.M., Osada, M., Kishida et al. (2010). Estrogens disrupt serotonin receptor and cyclooxygenase mRNA expression in the gonads of mussels (Mytilus edulis). Aquat. Toxicol. 98: 178-187. DOI: 10.1016/j.aquatox.2010.02.007. Cubero-Leon,E.Ciocan,C.M.Hill,E.M.Osada,M.Kishida 2010Estrogens disrupt serotonin receptor and cyclooxygenase mRNA expression in the gonads of mussels (Mytilus edulis).Aquat. Toxicol.9817818710.1016/j.aquatox.2010.02.007.Open DOISearch in Google Scholar

Dabrowska, H., Kopko, O., Turja, R., Lehtonen, K.K., Góra, A. et al. (2013). Sediment contaminants and contaminant levels and biomarkers in caged mussels (Mytilus trossulus) in the southern Baltic Sea. Mar. Environ. Res. 84: 1-9. DOI: 10.1016/j.marenvres.2012.11.001. Dabrowska,H.Kopko,O.Turja,R.Lehtonen,K.K.Góra,A.2013Sediment contaminants and contaminant levels and biomarkers in caged mussels (Mytilus trossulus) in the southern Baltic Sea.Mar. Environ. Res841910.1016/j.marenvres.2012.11.001.Open DOISearch in Google Scholar

Edebo, L., Haamer, J., Lindahl, O., Loo, L.O. & Piriz, L. (2000). Recycling of macronutrients from sea to land using mussel cultivation. Int. J. Environ. Pollut.13: 190-207. DOI: 10.1504/IJEP.2000.002315. Edebo,L.Haamer,J.Lindahl,O.Loo,L.O.Piriz,L.2000Recycling of macronutrients from sea to land using mussel cultivation.Int. J. Environ. Pollut.1319020710.1504/IJEP.2000.002315.Open DOISearch in Google Scholar

Ericson, H., Thorson, G. & Kumblad, L. (2010). Physiological Effects of diclofenac, ibuprofen and propranolol on Baltic Sea blue mussels. Aquat. Toxicol. 99: 223-231. DOI: 10.1016/j.aquatox.2010.04.017. Ericson,H.Thorson,G.Kumblad,L.2010Physiological Effects of diclofenac, ibuprofen and propranolol on Baltic Sea blue mussels.Aquat. Toxicol9922323110.1016/j.aquatox.2010.04.017Open DOISearch in Google Scholar

Gagné, F., André, C., Fortier, M. & Fournier, M. (2012). Immunotoxic potential of aeration lagoon effluents for the treatment of domestic and hospital wastewaters in the freshwater mussel Elliptio complanata. J. Environ. Sci. 24: 781-789. DOI: 10.1016/S1001-0742(11)60862-0. Gagné,F.André,C.,Fortier,M.Fournier,M.2012Immunotoxic potential of aeration lagoon effluents for the treatment of domestic and hospital wastewaters in the freshwater mussel Elliptio complanata.J. Environ. Sci.2478178910.1016/S1001-0742(11)60862-0.Open DOISearch in Google Scholar

Gagne, F., Berube, E., Fournier, M. & Blaise, C. (2005). Inflammatory properties of municipal effluents to Elliptio complanata mussels - Lack of Effects from anti-inflammatory drugs. Comp. Biochem. Physiol. Part C: Toxicol. Pharmacol. 141: 332-337. DOI: 10.1016/j.cca.2005.06.006. Gagne,F.Berube,E.Fournier,M.Blaise,C.2005Inflammatory properties of municipal effluents to Elliptio complanata mussels - Lack of Effects from anti-inflammatory drugs.Comp. Biochem. Physiol. Part C: Toxicol. Pharmacol.14133233710.1016/j.cca.2005.06.006.Open DOISearch in Google Scholar

Galassi, S., Bettinetti, R., Neri, M.C., Jeannot, R., Dagnac, T. et al. (2008). A multispecies approach for monitoring persistent toxic substances in the Gulf of Gdańsk (Baltic sea). Ecotoxicol. Environ. Saf. 69: 39-48. DOI: 10.1016/j. ecoenv.2006.11.015. Galassi,S.Bettinetti,R.Neri,M.C.Jeannot,R.Dagnac,T.2008A multispecies approach for monitoring persistent toxic substances in the Gulf of Gdańsk (Baltic sea).Ecotoxicol. Environ. Saf69394810.1016/j. ecoenv.2006.11.015Open DOISearch in Google Scholar

Gonzalez-Rey, M. & Bebianno, M.J. (2012). Does non-steroidal anti-inflammatory (NSAID) ibuprofen induce antioxidant stress and endocrine disruption in mussel Mytilus galloprovincialis? Environ. Toxicol. Pharmacol. 33: 361-371. DOI: 10.1016/j.etap.2011.12.017. Gonzalez-Rey,M.Bebianno,M.J.2012Does non-steroidal anti-inflammatory (NSAID) ibuprofen induce antioxidant stress and endocrine disruption in mussel Mytilus galloprovincialis?Environ. Toxicol. Pharmacol3336137110.1016/j.etap.2011.12.017.Open DOISearch in Google Scholar

Gonzalez-Rey, M. & Bebianno, M.J. (2014). Effects of nonsteroidal anti-inflammatory drug (NSAID) diclofenac exposure in mussel Mytilus galloprovincialis. Aquat. Toxicol. 148: 818-831. DOI: 10.1016/j.aquatox.2014.01.011. Gonzalez-Rey,M.Bebianno,M.J.2014Effects of nonsteroidal anti-inflammatory drug (NSAID) diclofenac exposure in mussel Mytilus galloprovincialis.Aquat. Toxicol.14881883110.1016/j.aquatox.2014.01.011.Open DOISearch in Google Scholar

Goverment of Canada. (1999). Canadian Environmental Protection Act, 1999. Canada Gazette Part III.22. Public Works and Goverments Service, Canada, Ottawa, Ont., Canada. pp. 249. Goverment of Canada.1999Canadian Environmental Protection Act, 1999. Canada Gazette Part III.22. Public Works and Goverments ServiceCanada, Ottawa, OntCanada249Search in Google Scholar

Halldórsson, H.P., Svavarsson, J. & Granmo, A. (2005). The Effect of pollution on scope for growth of the mussel (Mytilus edulis L.) in Iceland. Mar. Environ. Res. 59: 47-64. DOI: 10.1016/j.marenvres.2004.02.001. Halldórsson,H.P.,Svavarsson,J.Granmo,A.2005The Effect of pollution on scope for growth of the mussel (Mytilus edulis L.) in Iceland.Mar. Environ. Res59476410.1016/j.marenvres.2004.02.001.Open DOISearch in Google Scholar

Hallmann, A., Smolarz, K., Konieczna, L., Zabrzańska, S., Belka, M. et al. (2016). LC-MS measurment of free steroids in mussels (Mytilus trossulus) from the southern Baltic Sea. J. Pharm. Biomed. Anal. 117: 311-315. DOI:10.1016/j. jpba.2015.09.013. Hallmann,A.Smolarz,K.Konieczna,L.Zabrzańska,S.,Belka,M.2016LC-MS measurment of free steroids in mussels (Mytilus trossulus) from the southern Baltic Sea.J. Pharm. Biomed. Anal11731131510.1016/j. jpba.2015.09.013Open DOISearch in Google Scholar

HELCOM Helsinki Commission (2010). Hazardous substances in the Baltic Sea. HELCOM Helsinki Commission2010Hazardous substances in the Baltic SeaSearch in Google Scholar

Kallio, J.M., Lahti, M., Oikari, A. & Kronberg, L. (2010). Metabolites of the aquatic pollutant diclofenac in fish bile. Environ. Sci. Technol. 44: 7213-7219. DOI: 10.1021/es903402c. Kallio,J.M.Lahti,M.Oikari,A.Kronberg,L.2010Metabolites of the aquatic pollutant diclofenac in fish bile.Environ. Sci. Technol447213721910.1021/es903402c.Open DOISearch in Google Scholar

Kautsky, N. & Andersson, S. (1997). The Baltic Sea environment, and its sensitivity to pollutants with emphasis on organic tin compounds. KemI (Swedish Chemicals Agency) PM 3/97. Kautsky,N.Andersson,S.1997The Baltic Sea environment, and its sensitivity to pollutants with emphasis on organic tin compounds.KemI (Swedish Chemicals Agency) PM 3/97Search in Google Scholar

Kumirska, J., Migowska, N., Caban, M., Łukaszewicz, P. & Stepnowski, P. (2015). Simultaneous determination of non-steroidal anti-inflammatory drugs and oestrogenic hormones in environmental solid samples. Sci. Total Environ. 508: 498-505. DOI: 10.1016/j.scitotenv.2014.12.020. Kumirska,J.Migowska,N.Caban,M.Łukaszewicz,P.Stepnowski,P.2015Simultaneous determination of non-steroidal anti-inflammatory drugs and oestrogenic hormones in environmental solid samples.Sci. Total Environ50849850510.1016/j.scitotenv.2014.12.020.Open DOISearch in Google Scholar

Lachance, A.A., Myrand, B., Tremblay, R., Koutitonsky, V. & Carrington, E. (2008). Biotic and abiotic factors influencing attachment strength of blue mussels Mytilus edulis in suspended culture. Aquat. Biol. 2: 119-129. DOI: 10.3354/ab00041. Lachance,A.A.Myrand,B.Tremblay,R.Koutitonsky,V.Carrington,E.2008Biotic and abiotic factors influencing attachment strength of blue mussels Mytilus edulis in suspended culture.Aquat. Biol.211912910.3354/ab00041.Open DOISearch in Google Scholar

Lara-Martin, P.A., Gonzalez-Mazo, E., Petrovic, M., Barcelo, D. & Brownawell, B.J. (2014). Occurrence, distribution and partitioning of nonionic surfactants and pharmaceuticals in the urbanized Long Island Sound Estuary (NY). Mar. Pollut. Bull. 85: 710-719. DOI: 10.1016/j.marpolbul.2014.01.022. Lara-Martin,P.A.Gonzalez-Mazo,E.Petrovic,M.Barcelo,D.Brownawell,B.J.2014Occurrence, distribution and partitioning of nonionic surfactants and pharmaceuticals in the urbanized Long Island Sound Estuary (NY).Mar. Pollut. Bull.8571071910.1016/j.marpolbul.2014.01.022.Open DOISearch in Google Scholar

Li, H., Helm, P.A. & Metcalfe, C.D. (2010). Sampling in the great lakes for pharmaceuticals, personal care products, and endocrine-disrupting substances using the passive polar organic chemical integrative sampler. Environ. Toxicol. Chem. 29: 751-762. DOI: 10.1002/etc.104. Li,H.Helm,P.A.Metcalfe,C.D.2010Sampling in the great lakes for pharmaceuticals, personal care products, and endocrine-disrupting substances using the passive polar organic chemical integrative sampler.Environ. Toxicol. Chem.2975176210.1002/etc.10420821503Open DOISearch in Google Scholar

Lindahl, O., Hart, R., Hernroth, B., Kollberg, S., Loo, L.-O. et al. (2005). Improving Marine Water Quality by Mussel Farming: A Profitable Solution for Swedish Society. J. Hum. Environ. 34: 131-138. Lindahl,O.Hart,R.Hernroth,B.Kollberg,S.Loo,L.-O.2005Improving Marine Water Quality by Mussel Farming: A Profitable Solution for Swedish Society.J. Hum. Environ3413113810.1579/0044-7447-34.2.131Search in Google Scholar

McEneff , G., Barron, L., Kelleher, B., Paull, B. & Quinn, B. (2013). The determination of pharmaceutical residues in cooked and uncooked marine bivalves using pressurised liquid extraction, solid-phase extraction and liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 405: 9509-9521. DOI: 10.1007/s00216-013-7371-6. McEneff ,G.Barron,L.Kelleher,B.Paull,B.Quinn,B.2013The determination of pharmaceutical residues in cooked and uncooked marine bivalves using pressurisedliquid extraction, solid-phase extraction and liquid chromatography-tandem mass spectrometry.Anal. Bioanal. Chem.4059509952110.1007/s00216-013-7371-6.Open DOISearch in Google Scholar

McEneff , G., Barron, L., Kelleher, B., Paull, B. & Quinn, B. (2014). A year-long study of the spatial occurrence and relative distribution of pharmaceutical residues in sewage effluent, receiving marine waters and marine bivalves. Sci. Total Environ. 476-477: 317-326. DOI: 10.1016/j. scitotenv.2013.12.123. McEneff ,G.Barron,L.Kelleher,B.Paull,B.Quinn,B.2014A year-long study of the spatial occurrence and relative distribution of pharmaceutical residues in sewage effluent, receiving marine waters and marine bivalves.Sci. Total Environ.47647731732610.1016/j. scitotenv.2013.12.123Open DOISearch in Google Scholar

Migowska, N., Caban, M., Stepnowski, P., Kumirska, J. (2012). Simultaneous analysis of non-steroidal anti-inflammatory drugs and estrogenic hormones in water and wastewater samples using gas chromatography-mass spectrometry and gas chromatography with electron capture detection. Sci. Total Environ. 441: 77-88. DOI: 10.1016/j. scitotenv.2012.09.043. Migowska,N.Caban,M.Stepnowski,P.Kumirska,J.2012Simultaneous analysis of non-steroidal anti-inflammatory drugs and estrogenic hormones in water and wastewater samples using gas chromatography-mass spectrometry and gas chromatography with electron capture detection.Sci. Total Environ441778810.1016/j. scitotenv.2012.09.043.Open DOISearch in Google Scholar

Netherton, M. (2011). Uptake and metabolism of pharmaceuticals in aquatic invertebrates. PhD thesis, University of York. Netherton,M.2011Uptake and metabolism of pharmaceuticals in aquatic invertebratesPhD thesisUniversity of YorkSearch in Google Scholar

Newell, R.I.E. (2004). Ecosystem influences of natural and cultivated populations of suspension-feeding bivalve molluscs: A review. J. Shellfish Res. 23: 51-61. Newell,R.I.E.2004Ecosystem influences of natural and cultivated populations of suspension-feeding bivalve molluscs: A review.J. Shellfish Res.235161Search in Google Scholar

Nikolaou, A., Meric, S. & Fatta, D. (2007). Occurrence patterns of pharmaceuticals in water and wastewater environments. Anal. Bioanal. Chem. 387: 1225-1234. DOI: 10.1007/s00216-006-1035-8. Nikolaou,A.Meric,S.Fatta,D.2007Occurrence patterns of pharmaceuticals in water and wastewater environments.Anal. Bioanal. Chem.3871225123410.1007/s00216-006-1035-817205270Open DOISearch in Google Scholar

Nödler, K., Voutsa, D. & Licha, T. (2014). Polar organic micropollutants in the coastal environment of different marine systems. Mar. Pollut. Bull. 85: 50-59. DOI: 10.1016/j. marpolbul.2014.06.024. Nödler,K.Voutsa,D.Licha,T.2014Polar organic micropollutants in the coastal environment of different marine systems.Mar. Pollut. Bull85505910.1016/j. marpolbul.2014.06.024.Open DOISearch in Google Scholar

Norling, P. & Kautsky, N. (2008). Patches of the mussel Mytilus sp. are islands of high biodiversity in subtidal sediment habitats in the Baltic sea. Aquat. Biol. 4: 75-87. DOI: 10.3354/ab00096. Norling,P.Kautsky,N.2008Patches of the mussel Mytilus sp. are islands of high biodiversity in subtidal sediment habitats in the Baltic sea.Aquat. Biol.4758710.3354/ab00096.Open DOISearch in Google Scholar

Olenycz, M., Sokołowski, A., Niewińska, A., Wołowicz, M., Namieśnik et al. (2015). Comparison of PCBs and PAHs levels in European coastal waters using mussels from the Mytilus edulis complex as biomonitors: Production and mortality rates. Oceanologia 57(2):196-211. DOI: 10.1016/j. oceano.2014.12.001. Olenycz,M.Sokołowski,A.,Niewińska,A.,Wołowicz,M.,Namieśnik2015Comparison of PCBs and PAHs levels in European coastal waters using mussels from the Mytilus edulis complex as biomonitors: Production and mortality rates.Oceanologia575719621110.1016/j. oceano.2014.12.001.Open DOISearch in Google Scholar

Oskarsson, H., Wiklund, A.K.E., Thorsén, G., Danielsson, G. & Kumblad, L. (2014). Community interactions modify the Effects of pharmaceutical exposure: A microcosm study on responses to propranolol in Baltic Sea coastal organisms. PLoS One 9. DOI: 10.1371/journal.pone.0093774. Oskarsson,H.Wiklund,A.K.E.Thorsén,G.,Danielsson,G.Kumblad,L.2014Community interactions modify the Effects of pharmaceutical exposure: A microcosm study on responses to propranolol in Baltic Sea coastal organisms.PLoS One 9.10.1371/journal.pone.0093774.Open DOISearch in Google Scholar

Parolini, M., Binelli, A., Cogni, D. & Provini, A. (2010). Multi-biomarker approach for the evaluation of the cytogenotoxicity of paracetamol on the zebra mussel (Dreissena polymorpha). Chemosphere 79: 489-498. DOI: 10.1016/j.chemosphere.2010.02.053. Parolini,M.Binelli,A.Cogni,D.Provini,A.2010Multi-biomarker approach for the evaluation of the cytogenotoxicity of paracetamol on the zebra mussel (Dreissena polymorpha).Chemosphere7948949810.1016/j.chemosphere.2010.02.053.Open DOISearch in Google Scholar

Parolini, M., Binelli, A. & Provini, A. (2011). Chronic Effects induced by ibuprofen on the freshwater bivalve Dreissena polymorpha. Ecotoxicol. Environ. Saf. 74: 1586-1594. DOI: 10.1016/j.ecoenv.2011.04.025. Parolini,M.Binelli,A.Provini,A.2011Chronic Effects induced by ibuprofen on the freshwater bivalve Dreissena polymorpha.Ecotoxicol. Environ. Saf.741586159410.1016/j.ecoenv.2011.04.025.Open DOISearch in Google Scholar

Pazdro, K., Borecka, M., Siedlewicz, G., Bia, A. & Stepnowski, P. (2016). Analysis of the Residues of Pharmaceuticals in Marine Environment : State-of the Art , Analytical Problems and Challenges. Current Analytical Chemistry 12. DOI: 10.2174/1573411012666151009193536. Pazdro,K.Borecka,M.Siedlewicz,G.Bia,A.Stepnowski,P.2016Analysis of the Residues of Pharmaceuticals in Marine Environment : State-of the Art , Analytical Problems and Challenges.Current Analytical Chemistry1210.2174/1573411012666151009193536Open DOISearch in Google Scholar

Pierscieniak, K., Grzymala, J., Wolowicz, M., Pierścieniak, K., Grzymała, J. et al. (2010). Differences in reproduction and condition of Macoma balthica and Mytilus trossulus in the Gulf of Gdansk (Southern Baltic Sea) under anthropogenic influences. Oceanol. Hydrobiol. St. 39: 17-32. DOI: 10.2478/v10009-010-0054-0. Pierscieniak,K.Grzymala,J.Wolowicz,M.Pierścieniak,K.,Grzymała,J.2010Differences in reproduction and condition of Macoma balthica and Mytilus trossulus in the Gulf of Gdansk (Southern Baltic Sea) under anthropogenic influences.Oceanol. Hydrobiol. St.39173210.2478/v10009-010-0054-0.Open DOISearch in Google Scholar

Pimiä, V., Kankaanpää, H. & Kononen, K. (1997). The first observation of okadaic acid in Mytilus edulis from the Gulf of Finland. Boreal Environ. Res. 2: 381-385. Pimiä,V.Kankaanpää,H.Kononen,K.1997The first observation of okadaic acid in Mytilus edulis from the Gulf of Finland.Boreal Environ. Res2381385Search in Google Scholar

Pojana, G., Gomiero, A., Jonkers, N. & Marcomini, A. (2007). Natural and synthetic endocrine disrupting compounds (EDCs) in water, sediment and biota of a coastal lagoon. Environ. Int. 33: 929-936. DOI: 10.1016/j.envint.2007.05.003. Pojana,G.Gomiero,A.Jonkers,N.Marcomini,A.2007Natural and synthetic endocrine disrupting compounds (EDCs) in water, sediment and biota of a coastal lagoon.Environ. Int.3392993610.1016/j.envint.2007.05.003Open DOISearch in Google Scholar

Rainbow, P.S., Wolowicz, M., Fialkowski, W., Smith, B.D. & Sokolowski, A. (2000). Biomonitoring of trace metals in the Gulf of Gdansk, using mussels (Mytilus trossulus) and barnacles (Balanus improvisus). Water Res. 34: 1823-1829. DOI: 10.1016/S0043-1354(99)00345-0. Rainbow,P.S.Wolowicz,M.Fialkowski,W.Smith,B.D.Sokolowski,A.2000Biomonitoring of trace metals in the Gulf of Gdansk, using mussels (Mytilus trossulus) and barnacles (Balanus improvisus).Water Res341823182910.1016/S0043-1354(99)00345-0Open DOISearch in Google Scholar

Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) is a European Union regulation. (2007). Riisgård, H.U., Egede, P.P. & Barreiro Saavedra, I. (2011). Feeding Behaviour of the Mussel, Mytilus edulis: New Observations, with a Minireview of Current Knowledge. J. Mar. Biol. 2011: 1-13. DOI: 10.1155/2011/312459. Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) is a European Union regulation.2007Riisgård,H.U.,Egede,P.P.Barreiro Saavedra,I.2011Feeding Behaviour of the Mussel, Mytilus edulis: New Observations, with a Minireview of Current Knowledge.J. Mar. Biol201111310.1155/2011/312459.Open DOISearch in Google Scholar

Schmidt, W., O’Rourke, K., Hernan, R. & Quinn, B. (2011). Effects of the pharmaceuticals gemfibrozil and diclofenac on the marine mussel (Mytilus spp.) and their comparison with standardized toxicity tests. Mar. Pollut. Bull. 62: 1389-1395. DOI: 10.1016/j.marpolbul.2011.04.043. Schmidt,W.O’Rourke,K.Hernan,R.Quinn,B.2011Effects of the pharmaceuticals gemfibrozil and diclofenac on the marine mussel (Mytilus spp.) and their comparison with standardized toxicity tests.Mar. Pollut. Bull.621389139510.1016/j.marpolbul.2011.04.043.Open DOISearch in Google Scholar

Smolarz, K., Wołowicz, M. & Stachnik, M. (2006). First record of the occurrence of “gill disease” in Mytilus edulis trossulus from the Gulf of Gdańsk (Baltic Sea, Poland). J. Invertebr. Pathol. 93: 207-209. DOI: 10.1016/j.jip.2006.07.005. Smolarz,K.Wołowicz,M.Stachnik,M.2006First record of the occurrence of “gill disease” in Mytilus edulis trossulus from the Gulf of Gdańsk (Baltic Sea, Poland).J. Invertebr. Pathol.9320720910.1016/j.jip.2006.07.005Open DOISearch in Google Scholar

Stewart, M., Olsen, G., Hickey, C.W., Ferreira, B., Jelia, A. et al. (2014). A survey of emerging contaminants in the estuarine receiving environment around Auckland, New Zealand. Sci. Total Environ. 468-469: 202-210. DOI: 10.1016/j.scitotenv.2013.08.039. Stewart,M.Olsen,G.Hickey,C.W.Ferreira,B.Jelia,A.2014A survey of emerging contaminants in the estuarine receiving environment around Auckland, New Zealand.Sci. Total Environ46846920221010.1016/j.scitotenv.2013.08.039.Open DOISearch in Google Scholar

Strogyloudi, E., Giannakourou, A., Legrand, C., Ruehl, A. & Graneli, E. (2006). Estimating the accumulation and transfer of Nodularia spumigena toxins by the blue mussel Mytilus edulis: An appraisal from culture and mesocosm experiments. Toxicon 48: 359-372. DOI: 10.1016/j. toxicon.2006.05.009. Strogyloudi,E.Giannakourou,A.Legrand,C.Ruehl,A.Graneli,E.2006Estimating the accumulation and transfer of Nodularia spumigena toxins by the blue mussel Mytilus edulis: An appraisal from culture and mesocosm experiments.Toxicon4835937210.1016/j. toxicon.2006.05.009.Open DOISearch in Google Scholar

Sui, Q., Cao, X., Lu, S., Zhao, W., Qiu, Z. et al. (2015). Occurrence, sources and fate of pharmaceuticals and personal care products in the groundwater: A review. Emerg. Contam. 1: 14-25. DOI: 10.1016/j.emcon.2015.07.001. Sui,Q.Cao,X.Lu,S.Zhao,W.Qiu,Z.2015Occurrence, sources and fate of pharmaceuticals and personal care products in the groundwater: A review.Emerg. Contam.1142510.1016/j.emcon.2015.07.001Open DOISearch in Google Scholar

Svensen, C., Strogyloudi, E., Riser, C.W., Dahlmann, J., Legrand C. et al. (2005). Reduction of cyanobacterial toxins through coprophagy in Mytilus edulis. Harmful Algae 4: 329-336. DOI: 10.1016/j.hal.2004.06.015. Svensen,C.Strogyloudi,E.Riser,C.W.Dahlmann,J.LegrandC.2005Reduction of cyanobacterial toxins through coprophagy in Mytilus edulis.Harmful Algae432933610.1016/j.hal.2004.06.015.Open DOISearch in Google Scholar

UNEP. (2001). Final act of the conference of plenipotentiaries on the Stockholm convention on persistence organic pollutants. In Proceeding of the Conference of Plenipotentiaries on the Stockholm Convention on Persistent Organic Pollutants, Stockholm, Sweden. United Nations Environmental Programme. UNEP.2001Final act of the conference of plenipotentiaries on the Stockholm convention on persistence organic pollutants. InProceeding of the Conference of Plenipotentiaries on the Stockholm Convention on Persistent Organic Pollutants, Stockholm, Sweden. United Nations Environmental Programme.Search in Google Scholar

U.S. EPA. (1996). Ecological Effects Test Guidelines OPPTS 850.1710 - Oyster BCF. U.S. EPA.1996Ecological Effects Test Guidelines OPPTS 850.1710 - Oyster BCFSearch in Google Scholar

U.S. EPA. (2000). Bioaccumulation testing and interpretation for the purpose of sediment quality assessment status and needs. U.S. EPA.2000Bioaccumulation testing and interpretation for the purpose of sediment quality assessment status and needsSearch in Google Scholar

Washington State Department of Ecology. (2004). Final Report: Washington State Polybrominated Diphenyl Ether (PBDE) Chemical Action Plan. Washington, US. Washington State Department of Ecology.2004Final Report: Washington State Polybrominated Diphenyl Ether (PBDE) Chemical Action PlanWashington, USSearch in Google Scholar

Widdows, J., Donkin, P., Staff , F.J., Matthiessen, P., Law, R.J. et al. (2002). Measurement of stress Effects (scope for growth) and contaminat levels in mussels (Mytilus edulis) collected from the Irish Sea. Mar. Environ. Res. 53: 327-356. DOI: 10.1016/S0141-1136(01)00120-9. Widdows,J.Donkin,P.Staff ,F.J.Matthiessen,P.Law,R.J.2002Measurement of stress Effects (scope for growth) and contaminat levels in mussels (Mytilus edulis) collected from the Irish Sea.Mar. Environ. Res.5332735610.1016/S0141-1136(01)00120-9.Open DOISearch in Google Scholar

Widdows, J., Nasci, C. & Fossato, V.U. (1997). Effects of pollution on the scope for growth of mussels (Mytilus galloprovincialis) from the Venice Lagoon, Italy. Mar. Environ. Res. 43: 69-79. DOI: 10.1016/0141-1136(96)00003-7. Widdows,J.Nasci,C.Fossato,V.U.1997Effects of pollution on the scope for growth of mussels (Mytilus galloprovincialis) from the Venice Lagoon, Italy.Mar. Environ. Res43697910.1016/0141-1136(96)00003-7Open DOISearch in Google Scholar

Willert, P.L. (2007). Assessment of the pharmaceutical market in Poland after accession to the European Union. Eur. J. Heal. Econ. 8: 347-357. DOI: 10.1007/s10198-006-0032-3. Willert,P.L.2007Assessment of the pharmaceutical market in Poland after accession to the European Union.Eur. J. Heal. Econ834735710.1007/s10198-006-0032-317186200Open DOISearch in Google Scholar

Wolowicz, M. & Sokolowski, A. (2006). Effect of eutrophication on the distribution and ecophysiology of the mussel Mytilus trossulus (Bivalvia) in southern Baltic Sea (the Gulf of Gdansk). Limnol. Oceanogr. 51: 580-590. Wolowicz,M.Sokolowski,A.2006Effect of eutrophication on the distribution and ecophysiology of the mussel Mytilus trossulus (Bivalvia) in southern Baltic Sea (the Gulf of Gdansk)Limnol. Oceanogr5158059010.4319/lo.2006.51.1_part_2.0580Search in Google Scholar

Xie, Z., Lu, G., Liu, J., Yan, Z., Ma, B. et al. (2015). Occurrence, bioaccumulation, and trophic magnification of pharmaceutically active compounds in Taihu Lake, China. Chemosphere 138: 140-147. DOI: 10.1016/j. chemosphere.2015.05.086. Xie,Z.Lu,G.Liu,J.Yan,Z.Ma,B.2015Occurrence, bioaccumulation, and trophic magnification of pharmaceutically active compounds in Taihu Lake, China.Chemosphere13814014710.1016/j. chemosphere.2015.05.086Open DOISearch in Google Scholar