<abstract xmlns="http://www.w3.org/1999/xhtml"><p> In this study, we carried out the clinical and laboratory research of severe PMS (premenstrual syndrome) treatment in premenopausal age women. Herein, 37 women were examined and observed before the beginning of treatment and three months after it. Medication containing micronized progesterone was used for treatment (sublingually, 100 mg from 11 to 25 days of menstrual cycle). After three months of micronized progesterone treatment, 86.5% of all women-participants of the study were observed to have full regression of clinical symptoms, while 13.5% of all patients were observed to have decrease in clinical symptoms of severe PMS. Moreover, hormonal research results revealed significant (1.3 times) decrease in LH (Luteinizing hormone) level and (1.3 times) increase in progesterone level after three months of treatment (р&lt;0.05). The high bio-accessibility of the medication and its natural structure made it possible to decrease the dose and avoid risks of hepatotoxicity.</p></abstract>

In this study, we carried out the clinical and laboratory research of severe PMS (premenstrual syndrome) treatment in premenopausal age women. Herein, 37 women were examined and observed before the beginning of treatment and three months after it. Medication containing micronized progesterone was used for treatment (sublingually, 100 mg from 11 to 25 days of menstrual cycle). After three months of micronized progesterone treatment, 86.5% of all women-participants of the study were observed to have full regression of clinical symptoms, while 13.5% of all patients were observed to have decrease in clinical symptoms of severe PMS. Moreover, hormonal research results revealed significant (1.3 times) decrease in LH (Luteinizing hormone) level and (1.3 times) increase in progesterone level after three months of treatment (р<0.05). The high bio-accessibility of the medication and its natural structure made it possible to decrease the dose and avoid risks of hepatotoxicity.

Using micronized progesterone for treatment of premenopausal age women suffering from severe premenstrual syndrome

Current Issues in Pharmacy and Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

In this study, we carried out the clinical and laboratory research of severe PMS (premenstrual syndrome) treatment in premenopausal age women. Herein, 37 women...

Using micronized progesterone for treatment of premenopausal age women suffering from severe premenstrual syndrome

Publicado en línea: 29 dic 2017

Páginas: 138 - 141

Recibido: 13 jun 2017

Aceptado: 10 oct 2017

DOI: https://doi.org/10.1515/cipms-2017-0025

Palabras clave
PMS, treatment, per menopause, micronized progesterone

© 2018

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Using micronized progesterone for treatment of premenopausal age women suffering from severe premenstrual syndrome

Publicado en línea: 29 dic 2017

Páginas: 138 - 141

Recibido: 13 jun 2017

Aceptado: 10 oct 2017

DOI: https://doi.org/10.1515/cipms-2017-0025

Palabras clavePMS, treatment, per menopause, micronized progesterone

© 2018

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Palabras clave
PMS, treatment, per menopause, micronized progesterone