<abstract xmlns="http://www.w3.org/1999/xhtml"><p> In this study, we carried out the clinical and laboratory research of severe PMS (premenstrual syndrome) treatment in premenopausal age women. Herein, 37 women were examined and observed before the beginning of treatment and three months after it. Medication containing micronized progesterone was used for treatment (sublingually, 100 mg from 11 to 25 days of menstrual cycle). After three months of micronized progesterone treatment, 86.5% of all women-participants of the study were observed to have full regression of clinical symptoms, while 13.5% of all patients were observed to have decrease in clinical symptoms of severe PMS. Moreover, hormonal research results revealed significant (1.3 times) decrease in LH (Luteinizing hormone) level and (1.3 times) increase in progesterone level after three months of treatment (р&lt;0.05). The high bio-accessibility of the medication and its natural structure made it possible to decrease the dose and avoid risks of hepatotoxicity.</p></abstract>

In this study, we carried out the clinical and laboratory research of severe PMS (premenstrual syndrome) treatment in premenopausal age women. Herein, 37 women were examined and observed before the beginning of treatment and three months after it. Medication containing micronized progesterone was used for treatment (sublingually, 100 mg from 11 to 25 days of menstrual cycle). After three months of micronized progesterone treatment, 86.5% of all women-participants of the study were observed to have full regression of clinical symptoms, while 13.5% of all patients were observed to have decrease in clinical symptoms of severe PMS. Moreover, hormonal research results revealed significant (1.3 times) decrease in LH (Luteinizing hormone) level and (1.3 times) increase in progesterone level after three months of treatment (р<0.05). The high bio-accessibility of the medication and its natural structure made it possible to decrease the dose and avoid risks of hepatotoxicity.

Using micronized progesterone for treatment of premenopausal age women suffering from severe premenstrual syndrome

Current Issues in Pharmacy and Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

In this study, we carried out the clinical and laboratory research of severe PMS (premenstrual syndrome) treatment in premenopausal age women. Herein, 37 women...

Using micronized progesterone for treatment of premenopausal age women suffering from severe premenstrual syndrome

Published Online: Dec 29, 2017

Page range: 138 - 141

Received: Jun 13, 2017

Accepted: Oct 10, 2017

DOI: https://doi.org/10.1515/cipms-2017-0025

Keywords
PMS, treatment, per menopause, micronized progesterone

© 2018

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Using micronized progesterone for treatment of premenopausal age women suffering from severe premenstrual syndrome

Published Online: Dec 29, 2017

Page range: 138 - 141

Received: Jun 13, 2017

Accepted: Oct 10, 2017

DOI: https://doi.org/10.1515/cipms-2017-0025

KeywordsPMS, treatment, per menopause, micronized progesterone

© 2018

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
PMS, treatment, per menopause, micronized progesterone