Insufficient physical activity increases cardiovascular risk in women with low birth mass

Study aim: The aim of the study was to evaluate the relationship between low birth mass and concentration of high-sensitivity C-reactive protein (hsCRP) as a cardiovascular risk factor in young women with various levels of physical activity.

Materials and methods: 102 female students aged 19.7 ± 0.8 (18.6-23.0) were included. The study group was divided according to the declared physical activity: high physical activity (HPA, n = 69) and low physical activity (LPA, n = 33). Anthropometric indices were measured: body mass, height, hip and waist circumference. hsCRP levels were obtained from venous blood samples. Birth body mass (BBM) and birth height were collected from medical documentation.

Results: Women with low BBM and LPA had a significantly higher concentration of hsCRP than women with low BBM and HPA, as well as women with normal BBM.

Conclusions: Low birth mass together with low physical activity is a strong predictor of raised concentration of hsCRP, which correlates with an increased risk of cardiovascular and metabolic diseases. Regular physical activity in women with low birth mass may prevent an increased hsCRP concentration, and as a result decrease the risk of cardiovascular and metabolic diseases.