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Age-Related Dynamics of Fecal Microbiota in the Captive Chimpanzee (Pan troglodytes)

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16. Sept. 2025

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Aakko J, Pietilä S, Toivonen R, Rokka A, Mokkala K, Laitinen K, Elo L, Hänninen A. A carbohydrate-active enzyme (CAZy) profile links successful metabolic specialization of Prevotella to its abundance in gut microbiota. Sci Rep. 2020;10(1):12411. https://doi.org/10.1038/s41598-020-69241-2 Aakko J Pietilä S Toivonen R Rokka A Mokkala K Laitinen K Elo L Hänninen A. A carbohydrate-active enzyme (CAZy) profile links successful metabolic specialization of Prevotella to its abundance in gut microbiota . Sci Rep . 2020 ; 10 ( 1 ): 12411 . https://doi.org/10.1038/s41598-020-69241-2 Search in Google Scholar

Abeli T, Dalrymple S, Godefroid S, Mondoni A, Müller JV, Rossi G, Orsenigo S. Ex situ collections and their potential for the restoration of extinct plants. Conserv Biol. 2020;34(2):303–313. https://doi.org/10.1111/cobi.13391 Abeli T Dalrymple S Godefroid S Mondoni A Müller JV Rossi G Orsenigo S. Ex situ collections and their potential for the restoration of extinct plants . Conserv Biol . 2020 ; 34 ( 2 ): 303 313 . https://doi.org/10.1111/cobi.13391 Search in Google Scholar

Accetto T, Avguštin G. The diverse and extensive plant polysaccharide degradative apparatuses of the rumen and hindgut Prevotella species: A factor in their ubiquity? Syst Appl Microbiol. 2019;42(2):107–116. https://doi.org/10.1016/j.syapm.2018.10.001 Accetto T Avguštin G. The diverse and extensive plant polysaccharide degradative apparatuses of the rumen and hindgut Prevotella species: A factor in their ubiquity? Syst Appl Microbiol . 2019 ; 42 ( 2 ): 107 116 . https://doi.org/10.1016/j.syapm.2018.10.001 Search in Google Scholar

Altschul DM, Wallace EK, Sonnweber R, Tomonaga M, Weiss A. Chimpanzee intellect: Personality, performance and motivation with touchscreen tasks. R Soc Open Sci. 2017;4(5):170169. https://doi.org/10.1098/rsos.170169 Altschul DM Wallace EK Sonnweber R Tomonaga M Weiss A. Chimpanzee intellect: Personality, performance and motivation with touchscreen tasks . R Soc Open Sci . 2017 ; 4 ( 5 ): 170169 . https://doi.org/10.1098/rsos.170169 Search in Google Scholar

Amato KR, Lake BR, Ozminkowski S, Jiang H, Moy M, Sardaro MLS, Fultz A, Hopper LM. Exploring the utility of the gut microbiome as a longitudinal health monitoring tool in sanctuary chimpanzees (Pan troglodytes). Am J Primatol. 2025;87(3):e70004. https://doi.org/10.1002/ajp.70004 Amato KR Lake BR Ozminkowski S Jiang H Moy M Sardaro MLS Fultz A Hopper LM. Exploring the utility of the gut microbiome as a longitudinal health monitoring tool in sanctuary chimpanzees (Pan troglodytes) . Am J Primatol . 2025 ; 87 ( 3 ): e70004 . https://doi.org/10.1002/ajp.70004 Search in Google Scholar

Aragón-Vela J, Solis-Urra P, Ruiz-Ojeda FJ, Álvarez-Mercado AI, Olivares-Arancibia J, Plaza-Diaz J. Impact of exercise on gut microbiota in obesity. Nutrients. 2021;13(11):3999. https://doi.org/10.3390/nu13113999 Aragón-Vela J Solis-Urra P Ruiz-Ojeda FJ Álvarez-Mercado AI Olivares-Arancibia J Plaza-Diaz J. Impact of exercise on gut microbiota in obesity . Nutrients . 2021 ; 13 ( 11 ): 3999 . https://doi.org/10.3390/nu13113999 Search in Google Scholar

AZA Ape TAG. Chimpanzee (Pan troglodytes) care manual. Silver Spring (USA): Association of Zoos and Aquariums; 2010. AZA Ape TAG. Chimpanzee (Pan troglodytes) care manual . Silver Spring (USA) : Association of Zoos and Aquariums ; 2010 . Search in Google Scholar

Bakour S, Rathored J, Lo CI, Mediannikov O, Beye M, Ehounoud CB, Biagini P, Raoult D, Fournier PE, Fenollar F. Non-contiguous finished genome sequence and description of Streptococcus varani sp. nov. New Microbes New Infect. 2016;11:93–102. https://doi.org/10.1016/j.nmni.2016.03.004 Bakour S Rathored J Lo CI Mediannikov O Beye M Ehounoud CB Biagini P Raoult D Fournier PE Fenollar F. Non-contiguous finished genome sequence and description of Streptococcus varani sp. nov . New Microbes New Infect . 2016 ; 11 : 93 102 . https://doi.org/10.1016/j.nmni.2016.03.004 Search in Google Scholar

Baniel A, Petrullo L, Mercer A, Reitsema L, Sams S, Beehner JC, Bergman TJ, Snyder-Mackler N, Lu A. Maternal effects on early-life gut microbiota maturation in a wild nonhuman primate. Curr Biol. 2022;32(20):4508–4520.e6. https://doi.org/10.1016/j.cub.2022.08.037 Baniel A Petrullo L Mercer A Reitsema L Sams S Beehner JC Bergman TJ Snyder-Mackler N Lu A. Maternal effects on early-life gut microbiota maturation in a wild nonhuman primate . Curr Biol . 2022 ; 32 ( 20 ): 4508 4520.e6 . https://doi.org/10.1016/j.cub.2022.08.037 Search in Google Scholar

Cabana F, Jasmi R, Maguire R. Great ape nutrition: low-sugar and high-fibre diets can lead to increased natural behaviours, decreased regurgitation and reingestion, and reversal of prediabetes. Int. Zoo Yb. 2018;52:48–61. https://doi.org/10.1111/izy.12172 Cabana F Jasmi R Maguire R. Great ape nutrition: low-sugar and high-fibre diets can lead to increased natural behaviours, decreased regurgitation and reingestion, and reversal of prediabetes . Int. Zoo Yb . 2018 ; 52 : 48 61 . https://doi.org/10.1111/izy.12172 Search in Google Scholar

Campbell TP, Sun X, Patel VH, Sanz C, Morgan D, Dantas G. The microbiome and resistome of chimpanzees, gorillas, and humans across host lifestyle and geography. ISME J. 2020;14(6):1584– 1599. https://doi.org/10.1038/s41396-020-0634-2 Campbell TP Sun X Patel VH Sanz C Morgan D Dantas G. The microbiome and resistome of chimpanzees, gorillas, and humans across host lifestyle and geography . ISME J . 2020 ; 14 ( 6 ): 1584 1599 . https://doi.org/10.1038/s41396-020-0634-2 Search in Google Scholar

Cantwell A, Buckholtz JW, Atencia R, Rosati AG. The origins of cognitive flexibility in chimpanzees. Dev Sci. 2022 Sep;25(5):e13266. https://doi.org/10.1111/desc.1326 Cantwell A Buckholtz JW Atencia R Rosati AG. The origins of cognitive flexibility in chimpanzees . Dev Sci . 2022 Sep ; 25 ( 5 ): e13266 . https://doi.org/10.1111/desc.1326 Search in Google Scholar

Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, Fierer N, Peña AG, Goodrich JK, Gordon JI, et al. QIIME allows analysis of high-throughput community sequencing data. Nat Methods. 2010 May;7(5):335–336. https://doi.org/10.1038/nmeth.f.303 Caporaso JG Kuczynski J Stombaugh J Bittinger K Bushman FD Costello EK Fierer N Peña AG Goodrich JK Gordon JI QIIME allows analysis of high-throughput community sequencing data . Nat Methods . 2010 May ; 7 ( 5 ): 335 336 . https://doi.org/10.1038/nmeth.f.303 Search in Google Scholar

Carlsen F, de Jongh T, Pluháčková J. EAZA best practice guidelines for chimpanzees (Pan troglodytes) – 1st edition. Amsterdam (The Netherlands): European Association of Zoos and Aquariums; 2022. https://doi.org/10.61024/BPG2022ChimpanzeesEN Carlsen F de Jongh T Pluháčková J. EAZA best practice guidelines for chimpanzees (Pan troglodytes) – 1st edition . Amsterdam (The Netherlands) : European Association of Zoos and Aquariums ; 2022 . https://doi.org/10.61024/BPG2022ChimpanzeesEN Search in Google Scholar

Clayton JB, Vangay P, Huang H, Ward T, Hillmann BM, Al-Ghalith GA, Travis DA, Long HT, Tuan BV, Minh VV, et al. Captivity humanizes the primate microbiome. Proc Natl Acad Sci USA. 2016;113(37):10376–10381. https://doi.org/10.1073/pnas.1521835113 Clayton JB Vangay P Huang H Ward T Hillmann BM Al-Ghalith GA Travis DA Long HT Tuan BV Minh VV Captivity humanizes the primate microbiome . Proc Natl Acad Sci USA . 2016 ; 113 ( 37 ): 10376 10381 . https://doi.org/10.1073/pnas.1521835113 Search in Google Scholar

Costantini D, Masi S, Rachid L, Beltrame M, Rohmer M, Krief S. Mind the food: rapid changes in antioxidant content of diet affect oxidative status of chimpanzees. Am J Physiol Regul Integr Comp Physiol. 2021;320(5):R728–R734. https://doi.org/10.1152/ajpregu.00003.2021 Costantini D Masi S Rachid L Beltrame M Rohmer M Krief S. Mind the food: rapid changes in antioxidant content of diet affect oxidative status of chimpanzees . Am J Physiol Regul Integr Comp Physiol . 2021 ; 320 ( 5 ): R728 R734 . https://doi.org/10.1152/ajpregu.00003.2021 Search in Google Scholar

Degnan PH, Pusey AE, Lonsdorf EV, Goodall J, Wroblewski EE, Wilson ML, Rudicell RS, Hahn BH, Ochman H. Factors associated with the diversification of the gut microbial communities within chimpanzees from Gombe National Park. Proc Natl Acad Sci USA. 2012;109(32):13034–13039. https://doi.org/10.1073/pnas.1110994109 Degnan PH Pusey AE Lonsdorf EV Goodall J Wroblewski EE Wilson ML Rudicell RS Hahn BH Ochman H. Factors associated with the diversification of the gut microbial communities within chimpanzees from Gombe National Park . Proc Natl Acad Sci USA . 2012 ; 109 ( 32 ): 13034 13039 . https://doi.org/10.1073/pnas.1110994109 Search in Google Scholar

Dias BDC, Lamarca AP, Machado DT, Kloh VP, de Carvalho FM, Vasconcelos ATR. Metabolic pathways associated with Firmicutes prevalence in the gut of multiple livestock animals and humans. Anim Microbiome. 2025;7(1):20. https://doi.org/10.1186/s42523-025-00379-y Dias BDC Lamarca AP Machado DT Kloh VP de Carvalho FM Vasconcelos ATR. Metabolic pathways associated with Firmicutes prevalence in the gut of multiple livestock animals and humans . Anim Microbiome . 2025 ; 7 ( 1 ): 20 . https://doi.org/10.1186/s42523-025-00379-y Search in Google Scholar

Edgar RC. UPARSE: highly accurate OTU sequences from microbial amplicon reads. Nat Methods. 2013 Oct;10(10):996–998. https://doi.org/10.1038/nmeth.2604 Edgar RC. UPARSE: highly accurate OTU sequences from microbial amplicon reads . Nat Methods . 2013 Oct ; 10 ( 10 ): 996 998 . https://doi.org/10.1038/nmeth.2604 Search in Google Scholar

El Kaoutari A, Armougom F, Gordon JI, Raoult D, Henrissat B. The abundance and variety of carbohydrate-active enzymes in the human gut microbiota. Nat Rev Microbiol. 2013;11(7):497–504. https://doi.org/10.1038/nrmicro3050 El Kaoutari A Armougom F Gordon JI Raoult D Henrissat B. The abundance and variety of carbohydrate-active enzymes in the human gut microbiota . Nat Rev Microbiol . 2013 ; 11 ( 7 ): 497 504 . https://doi.org/10.1038/nrmicro3050 Search in Google Scholar

Fu L, Lou Y, Guo Y, Zhou F, Ma J, Wang S, Gu Y, Fu B, Lu W. Seminal plasma microbiomes, sperm parameters, and cryopreservation in a healthy fertile population. Front Microbiol. 2024;15:1401326. https://doi.org/10.3389/fmicb.2024.1401326 Fu L Lou Y Guo Y Zhou F Ma J Wang S Gu Y Fu B Lu W. Seminal plasma microbiomes, sperm parameters, and cryopreservation in a healthy fertile population . Front Microbiol . 2024 ; 15 : 1401326 . https://doi.org/10.3389/fmicb.2024.1401326 Search in Google Scholar

Goodall J. The chimpanzees of Gombe: patterns of behavior. Cambridge (USA): Harvard University Press; 1986. Goodall J. The chimpanzees of Gombe: patterns of behavior . Cambridge (USA) : Harvard University Press ; 1986 . Search in Google Scholar

Koliada A, Syzenko G, Moseiko V, Budovska L, Puchkov K, Perederiy V, Gavalko Y, Dorofeyev A, Romanenko M, Tkach S, et al. Association between body mass index and Firmicutes/Bacteroidetes ratio in an adult Ukrainian population. BMC Microbiol. 2017;17(1):120. https://doi.org/10.1186/s12866-017-1027-1 Koliada A Syzenko G Moseiko V Budovska L Puchkov K Perederiy V Gavalko Y Dorofeyev A Romanenko M Tkach S Association between body mass index and Firmicutes/Bacteroidetes ratio in an adult Ukrainian population . BMC Microbiol . 2017 ; 17 ( 1 ): 120 . https://doi.org/10.1186/s12866-017-1027-1 Search in Google Scholar

Komodromou I, Andreou E, Vlahoyiannis A, Christofidou M, Felekkis K, Pieri M, Giannaki CD. Exploring the dynamic relationship between the gut microbiome and body composition across the human lifespan: A systematic review. Nutrients. 2024;16(5):660. https://doi.org/10.3390/nu16050660 Komodromou I Andreou E Vlahoyiannis A Christofidou M Felekkis K Pieri M Giannaki CD. Exploring the dynamic relationship between the gut microbiome and body composition across the human lifespan: A systematic review . Nutrients . 2024 ; 16 ( 5 ): 660 . https://doi.org/10.3390/nu16050660 Search in Google Scholar

Kovatcheva-Datchary P, Nilsson A, Akrami R, Lee YS, De Vadder F, Arora T, Hallen A, Martens E, Björck I, Bäckhed F. Dietary fiber-induced improvement in glucose metabolism is associated with increased abundance of Prevotella. Cell Metab. 2015;22(6):971–982. https://doi.org/10.1016/j.cmet.2015.10.001 Kovatcheva-Datchary P Nilsson A Akrami R Lee YS De Vadder F Arora T Hallen A Martens E Björck I Bäckhed F. Dietary fiber-induced improvement in glucose metabolism is associated with increased abundance of Prevotella . Cell Metab . 2015 ; 22 ( 6 ): 971 982 . https://doi.org/10.1016/j.cmet.2015.10.001 Search in Google Scholar

Le HH, Lee MT, Besler KR, Comrie JMC, Johnson EL. Characterization of interactions of dietary cholesterol with the murine and human gut microbiome. Nat Microbiol. 2022;7(9):1390–1403. https://doi.org/10.1038/s41564-022-01195-9 Le HH Lee MT Besler KR Comrie JMC Johnson EL. Characterization of interactions of dietary cholesterol with the murine and human gut microbiome . Nat Microbiol . 2022 ; 7 ( 9 ): 1390 1403 . https://doi.org/10.1038/s41564-022-01195-9 Search in Google Scholar

Li Y, Xu X, Guo Z, Li Q, Wang Y, Jian D, Zhang G, Tian X, Chen S, Luo Z. Neonatal Streptococcus pneumoniae infection induces long-lasting dysbiosis of the gut microbiota in a mouse model. Front Microbiol. 2022;13:961684. https://doi.org/10.3389/fmicb.2022.961684 Li Y Xu X Guo Z Li Q Wang Y Jian D Zhang G Tian X Chen S Luo Z. Neonatal Streptococcus pneumoniae infection induces long-lasting dysbiosis of the gut microbiota in a mouse model . Front Microbiol . 2022 ; 13 : 961684 . https://doi.org/10.3389/fmicb.2022.961684 Search in Google Scholar

Litty D, Müller V. Butyrate production in the acetogen Eubacterium limosum is dependent on the carbon and energy source. Microb Biotechnol. 2021;14(6):2686–2692. https://doi.org/10.1111/1751-7915.13779 Litty D Müller V. Butyrate production in the acetogen Eubacterium limosum is dependent on the carbon and energy source . Microb Biotechnol . 2021 ; 14 ( 6 ): 2686 2692 . https://doi.org/10.1111/1751-7915.13779 Search in Google Scholar

Louis P, Flint HJ. Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine. FEMS Microbiol Lett. 2009;294(1):1–8. https://doi.org/10.1111/j.1574-6968.2009.01514.x Louis P Flint HJ. Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine . FEMS Microbiol Lett . 2009 ; 294 ( 1 ): 1 8 . https://doi.org/10.1111/j.1574-6968.2009.01514.x Search in Google Scholar

Magoč T, Salzberg SL. FLASH: fast length adjustment of short reads to improve genome assemblies. Bioinformatics. 2011 Nov;27(21):2957–2963. https://doi.org/10.1093/bioinformatics/btr507 Magoč T Salzberg SL. FLASH: fast length adjustment of short reads to improve genome assemblies . Bioinformatics . 2011 Nov ; 27 ( 21 ): 2957 2963 . https://doi.org/10.1093/bioinformatics/btr507 Search in Google Scholar

Moeller AH, Ochman H. Factors that drive variation among gut microbial communities. Gut Microbes. 2013 Sep-Oct;4(5):403-8. https://doi.org/10.4161/gmic.26039 Moeller AH Ochman H. Factors that drive variation among gut microbial communities . Gut Microbes . 2013 Sep-Oct ; 4 ( 5 ): 403 - 8 . https://doi.org/10.4161/gmic.26039 Search in Google Scholar

Moeller AH, Foerster S, Wilson ML, Pusey AE, Hahn BH, Ochman H. Social behavior shapes the chimpanzee pan-microbiome. Sci Adv. 2016;2(1):e1500997. https://doi.org/10.1126/sciadv.1500997 Moeller AH Foerster S Wilson ML Pusey AE Hahn BH Ochman H. Social behavior shapes the chimpanzee pan-microbiome . Sci Adv . 2016 ; 2 ( 1 ): e1500997 . https://doi.org/10.1126/sciadv.1500997 Search in Google Scholar

Mohamed Qadir R, Assafi MS. The association between body mass index and the oral Firmicutes and Bacteroidetes profiles of healthy individuals. Malays Fam Physician. 2021;16(3):36–43. https://doi.org/10.51866/oa1129 Mohamed Qadir R Assafi MS. The association between body mass index and the oral Firmicutes and Bacteroidetes profiles of healthy individuals . Malays Fam Physician . 2021 ; 16 ( 3 ): 36 43 . https://doi.org/10.51866/oa1129 Search in Google Scholar

Narat V, Amato KR, Ranger N, Salmona M, Mercier-Delarue S, Rupp S, Ambata P, Njouom R, Simon F, Giles-Vernick T, et al. A multi-disciplinary comparison of great ape gut microbiota in a central African forest and European zoo. Sci Rep. 2020;10(1):19107. https://doi.org/10.1038/s41598-020-75847-3 Narat V Amato KR Ranger N Salmona M Mercier-Delarue S Rupp S Ambata P Njouom R Simon F Giles-Vernick T A multi-disciplinary comparison of great ape gut microbiota in a central African forest and European zoo . Sci Rep . 2020 ; 10 ( 1 ): 19107 . https://doi.org/10.1038/s41598-020-75847-3 Search in Google Scholar

Nishida AH, Ochman H. A great-ape view of the gut microbiome. Nat Rev Genet. 2019;20(4):195–206. https://doi.org/10.1038/s41576-018-0085-z Nishida AH Ochman H. A great-ape view of the gut microbiome . Nat Rev Genet . 2019 ; 20 ( 4 ): 195 206 . https://doi.org/10.1038/s41576-018-0085-z Search in Google Scholar

Pan X, Liu F, Song Y, Wang H, Wang L, Qiu H, Price M, Li J. Motor stereotypic behavior was associated with immune response in macaques: Insight from transcriptome and gut microbiota analysis. Front Microbiol. 2021;12:644540. https://doi.org/10.3389/fmicb.2021.644540 Pan X Liu F Song Y Wang H Wang L Qiu H Price M Li J. Motor stereotypic behavior was associated with immune response in macaques: Insight from transcriptome and gut microbiota analysis . Front Microbiol . 2021 ; 12 : 644540 . https://doi.org/10.3389/fmicb.2021.644540 Search in Google Scholar

Pan X, Raaijmakers JM, Carrión VJ. Importance of Bacteroidetes in host-microbe interactions and ecosystem functioning. Trends Microbiol. 2023;31(9):959–971. https://doi.org/10.1016/j.tim.2023.03.018 Pan X Raaijmakers JM Carrión VJ. Importance of Bacteroidetes in host-microbe interactions and ecosystem functioning . Trends Microbiol . 2023 ; 31 ( 9 ): 959 971 . https://doi.org/10.1016/j.tim.2023.03.018 Search in Google Scholar

Pascual A, Kalcher-Sommersguter E, Riba D, Crailsheim D. Long-term assessment of captive chimpanzees: Influence of social group composition, seasonality and biographic background. Animals. 2023;13(3):424. https://doi.org/10.3390/ani13030424 Pascual A Kalcher-Sommersguter E Riba D Crailsheim D. Long-term assessment of captive chimpanzees: Influence of social group composition, seasonality and biographic background . Animals . 2023 ; 13 ( 3 ): 424 . https://doi.org/10.3390/ani13030424 Search in Google Scholar

Pusey AE, Oehlert GW, Williams JM, Goodall J. Influence of ecological and social factors on body mass of wild chimpanzees. Int J Primatol. 2005;26(1):3–31. https://doi.org/10.1007/s10764-005-0721-2 Pusey AE Oehlert GW Williams JM Goodall J. Influence of ecological and social factors on body mass of wild chimpanzees . Int J Primatol . 2005 ; 26 ( 1 ): 3 31 . https://doi.org/10.1007/s10764-005-0721-2 Search in Google Scholar

Quast C, Pruesse E, Yilmaz P, Gerken J, Schweer T, Yarza P, Peplies J, Glöckner FO. The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. Nucleic Acids Res. 2013 Jan;41(Database issue):D590–D596. https://doi.org/10.1093/nar/gks1219 Quast C Pruesse E Yilmaz P Gerken J Schweer T Yarza P Peplies J Glöckner FO. The SILVA ribosomal RNA gene database project: improved data processing and web-based tools . Nucleic Acids Res . 2013 Jan ; 41 (Database issue): D590 D596 . https://doi.org/10.1093/nar/gks1219 Search in Google Scholar

Reese AT, Phillips SR, Owens LA, Venable EM, Langergraber KE, Machanda ZP, Mitani JC, Muller MN, Watts DP, Wrangham RWet al. Age patterning in wild chimpanzee gut microbiota diversity reveals differences from humans in early life. Curr Biol. 2021;31(3):613–620.e3. https://doi.org/10.1016/j.cub.2020.10.075 Reese AT Phillips SR Owens LA Venable EM Langergraber KE Machanda ZP Mitani JC Muller MN Watts DP Wrangham RW Age patterning in wild chimpanzee gut microbiota diversity reveals differences from humans in early life . Curr Biol . 2021 ; 31 ( 3 ): 613 620.e3 . https://doi.org/10.1016/j.cub.2020.10.075 Search in Google Scholar

Ren D, Li L, Schwabacher AW, Young JW, Beitz DC. Mechanism of cholesterol reduction to coprostanol by Eubacterium coprostanoligenes ATCC 51222. Steroids. 1996;61(1):33–40. https://doi.org/10.1016/0039-128x(95)00173-n Ren D Li L Schwabacher AW Young JW Beitz DC. Mechanism of cholesterol reduction to coprostanol by Eubacterium coprostanoligenes ATCC 51222 . Steroids . 1996 ; 61 ( 1 ): 33 40 . https://doi.org/10.1016/0039-128x(95)00173-n Search in Google Scholar

Rivière A, Selak M, Lantin D, Leroy F, De Vuyst L. Bifidobacteria and butyrate-producing colon bacteria: Importance and strategies for their stimulation in the human gut. Front Microbiol. 2016;7:979. https://doi.org/10.3389/fmicb.2016.00979 Rivière A Selak M Lantin D Leroy F De Vuyst L. Bifidobacteria and butyrate-producing colon bacteria: Importance and strategies for their stimulation in the human gut . Front Microbiol . 2016 ; 7 : 979 . https://doi.org/10.3389/fmicb.2016.00979 Search in Google Scholar

Roth G. Convergent evolution of complex brains and high intelligence. Philos Trans R Soc Lond B Biol Sci. 2015;370(1684):20150049. https://doi.org/10.1098/rstb.2015.0049 Roth G. Convergent evolution of complex brains and high intelligence . Philos Trans R Soc Lond B Biol Sci . 2015 ; 370 ( 1684 ): 20150049 . https://doi.org/10.1098/rstb.2015.0049 Search in Google Scholar

Rouskas K, Guela M, Pantoura M, Pagkalos I, Hassapidou M, Lalama E, Pfeiffer AFH, Decorte E, Cornelissen V, Wilson-Barnes S, et al. The influence of an AI-driven personalized nutrition program on the human gut microbiome and its health implications. Nutrients. 2025;17(7):1260. https://doi.org/10.3390/nu17071260 Rouskas K Guela M Pantoura M Pagkalos I Hassapidou M Lalama E Pfeiffer AFH Decorte E Cornelissen V Wilson-Barnes S The influence of an AI-driven personalized nutrition program on the human gut microbiome and its health implications . Nutrients . 2025 ; 17 ( 7 ): 1260 . https://doi.org/10.3390/nu17071260 Search in Google Scholar

Staerk J, Colchero F, Kenney MA, Wilson KA, Foden WB, Carr JA, Pereboom Z, Bland L, Flesness N, Martin T, et al. A decision framework to integrate in-situ and ex-situ management for species in the European Union. Front Conserv Sci. 2024;4:1298850. https://doi.org/10.3389/fcosc.2023.1298850 Staerk J Colchero F Kenney MA Wilson KA Foden WB Carr JA Pereboom Z Bland L Flesness N Martin T A decision framework to integrate in-situ and ex-situ management for species in the European Union . Front Conserv Sci . 2024 ; 4 : 1298850 . https://doi.org/10.3389/fcosc.2023.1298850 Search in Google Scholar

Sun Y, Zhang S, Nie Q, He H, Tan H, Geng F, Ji H, Hu J, Nie S. Gut firmicutes: Relationship with dietary fiber and role in host homeostasis. Crit Rev Food Sci Nutr. 2023;63(33):12073–12088. https://doi.org/10.1080/10408398.2022.2098249 Sun Y Zhang S Nie Q He H Tan H Geng F Ji H Hu J Nie S. Gut firmicutes: Relationship with dietary fiber and role in host homeostasis . Crit Rev Food Sci Nutr . 2023 ; 63 ( 33 ): 12073 12088 . https://doi.org/10.1080/10408398.2022.2098249 Search in Google Scholar

Szekely BA, Singh J, Marsh TL, Hagedorn C, Werre SR, Kaur T. Fecal bacterial diversity of human-habituated wild chimpanzees (Pan troglodytes schweinfurthii) at Mahale Mountains National Park, Western Tanzania. Am J Primatol. 2010;72(7):566–574. https://doi.org/10.1002/ajp.20809 Szekely BA Singh J Marsh TL Hagedorn C Werre SR Kaur T. Fecal bacterial diversity of human-habituated wild chimpanzees (Pan troglodytes schweinfurthii) at Mahale Mountains National Park, Western Tanzania . Am J Primatol . 2010 ; 72 ( 7 ): 566 574 . https://doi.org/10.1002/ajp.20809 Search in Google Scholar

Tutin CEG, Fernandez M. Composition of the diet of chimpanzees and comparisons with that of sympatric lowland gorillas in the lopé reserve, gabon. Am J Primatol. 1993;30(3):195–211. https://doi.org/10.1002/ajp.1350300305 Tutin CEG Fernandez M. Composition of the diet of chimpanzees and comparisons with that of sympatric lowland gorillas in the lopé reserve, gabon . Am J Primatol . 1993 ; 30 ( 3 ): 195 211 . https://doi.org/10.1002/ajp.1350300305 Search in Google Scholar

van den Heuvel MP, Ardesch DJ, Scholtens LH, de Lange SC, van Haren NEM, Sommer IEC, Dannlowski U, Repple J, Preuss TM, Hopkins WD, et al. Human and chimpanzee shared and divergent neurobiological systems for general and specific cognitive brain functions. Proc Natl Acad Sci USA. 2023;120(22):e2218565120. https://doi.org/10.1073/pnas.2218565120 van den Heuvel MP Ardesch DJ Scholtens LH de Lange SC van Haren NEM Sommer IEC Dannlowski U Repple J Preuss TM Hopkins WD Human and chimpanzee shared and divergent neurobiological systems for general and specific cognitive brain functions . Proc Natl Acad Sci USA . 2023 ; 120 ( 22 ): e2218565120 . https://doi.org/10.1073/pnas.2218565120 Search in Google Scholar

Visser F, Drouilly M, Moodley Y, Michaux JR, Somers MJ. Mismatch between conservation needs and actual representation of Visser F Drouilly M Moodley Y Michaux JR Somers MJ. Mismatch between conservation needs and actual representation of Search in Google Scholar

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