Knocking Down LncRNA-GAS5 Restores the Inhibition of Cuprotosis Protein FDX-1 by Acinetobacter baumannii

An Z, Ding W. Acinetobacter baumannii up-regulates LncRNA-GAS5 and promotes the degradation of STX17 by blocking the activation of YY1. Virulence. 2021 Dec;12(1):1965–1979. https://doi.org/10.1080/21505594.2021.1953851 An Z Ding W. Acinetobacter baumannii up-regulates LncRNA-GAS5 and promotes the degradation of STX17 by blocking the activation of YY1 . Virulence . 2021 Dec ; 12 ( 1 ): 1965 – 1979 . https://doi.org/10.1080/21505594.2021.1953851 Search in Google Scholar

An Z, Huang X, Zheng C, Ding W. Acinetobacter baumannii outer membrane protein A induces HeLa cell autophagy via MAPK/JNK signaling pathway. Int J Med Microbiol. 2019a Mar;309(2):97–107. https://doi.org/10.1016/j.ijmm.2018.12.004 An Z Huang X Zheng C Ding W. Acinetobacter baumannii outer membrane protein A induces HeLa cell autophagy via MAPK/JNK signaling pathway . Int J Med Microbiol . 2019a Mar ; 309 ( 2 ): 97 – 107 . https://doi.org/10.1016/j.ijmm.2018.12.004 Search in Google Scholar

An Z, Su J. Acinetobacter baumannii outer membrane protein 34 elicits NLRP3 inflammasome activation via mitochondria-derived reactive oxygen species in RAW264.7 macrophages. Microbes Infect. 2019b Apr-May;21(3–4):143–153. https://doi.org/10.1016/j.micinf.2018.10.005 An Z Su J. Acinetobacter baumannii outer membrane protein 34 elicits NLRP3 inflammasome activation via mitochondria-derived reactive oxygen species in RAW264.7 macrophages . Microbes Infect . 2019b Apr-May ; 21 ( 3–4 ): 143 – 153 . https://doi.org/10.1016/j.micinf.2018.10.005 Search in Google Scholar

Gao Z, Huang D. lncRNA GAS5-mediated miR-23a-3p promotes inflammation and cell apoptosis by targeting TLR4 in a cell model of sepsis. Mol Med Rep. 2021 Jul;24(1):510. https://doi.org/10.3892/mmr.2021.12149 Gao Z Huang D. lncRNA GAS5-mediated miR-23a-3p promotes inflammation and cell apoptosis by targeting TLR4 in a cell model of sepsis . Mol Med Rep . 2021 Jul ; 24 ( 1 ): 510 . https://doi.org/10.3892/mmr.2021.12149 Search in Google Scholar

Harding CM, Hennon SW, Feldman MF. Uncovering the mechanisms of Acinetobacter baumannii virulence. Nat Rev Microbiol. 2018 Feb;16(2):91–102. https://doi.org/10.1038/nrmicro.2017.148 Harding CM Hennon SW Feldman MF. Uncovering the mechanisms of Acinetobacter baumannii virulence . Nat Rev Microbiol . 2018 Feb ; 16 ( 2 ): 91 – 102 . https://doi.org/10.1038/nrmicro.2017.148 Search in Google Scholar

Hu G, Lou Z, Gupta M. The long non-coding RNA GAS5 cooperates with the eukaryotic translation initiation factor 4E to regulate c-Myc translation. PLoS One. 2014 Sep;9(9):e107016. https://doi.org/10.1371/journal.pone.0107016 Hu G Lou Z Gupta M. The long non-coding RNA GAS5 cooperates with the eukaryotic translation initiation factor 4E to regulate c-Myc translation . PLoS One . 2014 Sep ; 9 ( 9 ): e107016 . https://doi.org/10.1371/journal.pone.0107016 Search in Google Scholar

Kino T, Hurt DE, Ichijo T, Nader N, Chrousos GP. Noncoding RNA gas5 is a growth arrest-and starvation-associated repressor of the glucocorticoid receptor. Sci Signal. 2010 Feb;3(107):ra8. https://doi.org/10.1126/scisignal.2000568 Kino T Hurt DE Ichijo T Nader N Chrousos GP. Noncoding RNA gas5 is a growth arrest-and starvation-associated repressor of the glucocorticoid receptor . Sci Signal . 2010 Feb ; 3 ( 107 ): ra8 . https://doi.org/10.1126/scisignal.2000568 Search in Google Scholar

Li J, Tian J, Lu J, Wang Z, Ling J, Wu X, Yang F, Xia Y. LncRNA GAS5 inhibits Th17 differentiation and alleviates immune thrombocytopenia via promoting the ubiquitination of STAT3. Int Immu-nopharmacol. 2020 Mar;80:106127. https://doi.org/10.1016/j.intimp.2019.106127 Li J Tian J Lu J Wang Z Ling J Wu X Yang F Xia Y. LncRNA GAS5 inhibits Th17 differentiation and alleviates immune thrombocytopenia via promoting the ubiquitination of STAT3 . Int Immu-nopharmacol . 2020 Mar ; 80 : 106127 . https://doi.org/10.1016/j.intimp.2019.106127 Search in Google Scholar

Li SR, Bu LL, Cai L. Cuproptosis: Lipoylated TCA cycle proteinsmediated novel cell death pathway. Signal Transduct Target Ther. 2022 May;7(1):158. https://doi.org/10.1038/s41392-022-01014-x Li SR Bu LL Cai L. Cuproptosis: Lipoylated TCA cycle proteins-mediated novel cell death pathway . Signal Transduct Target Ther . 2022 May ; 7 ( 1 ): 158 . https://doi.org/10.1038/s41392-022-01014-x Search in Google Scholar

Li Y, Guo X, Hu C, Du Y, Guo C, Di Wang, Zhao W, Huang G, Li C, Lu Q, et al. Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection. Cell Death Differ. 2018 Jul;25(7):1304–1318. https://doi.org/10.1038/s41418-017-0041-z Li Y Guo X Hu C Du Y Guo C Di Wang Zhao W Huang G Li C Lu Q et al. Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection . Cell Death Differ . 2018 Jul ; 25 ( 7 ): 1304 – 1318 . https://doi.org/10.1038/s41418-017-0041-z Search in Google Scholar

Meng H, Zhang T, Wang Z, Zhu Y, Yu Y, Chen H, Chen J, Wang F, Yu Y, Hua X, et al. High-throughput host-microbe single-cell RNA sequencing reveals ferroptosis-associated heterogeneity during Acinetobacter baumannii infection. Angew Chem Int Ed Engl. 2024 Apr;63(18):e202400538. https://doi.org/10.1002/anie.202400538 Meng H Zhang T Wang Z Zhu Y Yu Y Chen H Chen J Wang F Yu Y Hua X et al. High-throughput host-microbe single-cell RNA sequencing reveals ferroptosis-associated heterogeneity during Aci-netobacter baumannii infection . Angew Chem Int Ed Engl . 2024 Apr ; 63 ( 18 ): e202400538 . https://doi.org/10.1002/anie.202400538 Search in Google Scholar

Tsvetkov P, Coy S, Petrova B, Dreishpoon M, Verma A, Abdusamad M, Rossen J, Joesch-Cohen L, Humeidi R, Spangler RD, et al. Copper induces cell death by targeting lipoylated TCA cycle proteins. Science. 2022 Mar;375(6586):1254–1261. https://doi.org/10.1126/science.abf0529 Tsvetkov P Coy S Petrova B Dreishpoon M Verma A Abdusamad M Rossen J Joesch-Cohen L Humeidi R Spangler RD et al. Copper induces cell death by targeting lipoylated TCA cycle proteins . Science . 2022 Mar ; 375 ( 6586 ): 1254 – 1261 . https://doi.org/10.1126/science.abf0529 Search in Google Scholar

Yang X, Xie Z, Lei X, Gan R. Long non-coding RNA GAS5 in human cancer. Oncol Lett. 2020 Sep;20(3):2587–2594. https://doi.org/10.3892/ol.2020.11809 Yang X Xie Z Lei X Gan R. Long non-coding RNA GAS5 in human cancer . Oncol Lett . 2020 Sep ; 20 ( 3 ): 2587 – 2594 . https://doi.org/10.3892/ol.2020.11809 Search in Google Scholar

Zhang XC, Gu AP, Zheng CY, Li YB, Liang HF, Wang HJ, Tang XL, Bai XX, Cai J. YY1/LncRNA GAS5 complex aggravates cerebral ischemia/reperfusion injury through enhancing neuronal glycolysis. Neuropharmacology. 2019 Nov;158:107682. https://doi.org/10.1016/j.neuropharm.2019.107682 Zhang XC Gu AP Zheng CY Li YB Liang HF Wang HJ Tang XL Bai XX Cai J. YY1/LncRNA GAS5 complex aggravates cerebral ischemia/reperfusion injury through enhancing neuronal glycolysis . Neuropharmacology . 2019 Nov ; 158 : 107682 . https://doi.org/10.1016/j.neuropharm.2019.107682 Search in Google Scholar

Zhao D, Li Y, Peng C, Lin J, Yu F, Zhao Y, Zhang X, Zhao D. Outer membrane protein a in Acinetobacter baumannii induces autophagy through mTOR signalling pathways in the lung of SD rats. Biomed Pharmacother. 2021 Mar;135:111034. https://doi.org/10.1016/j.biopha.2020.111034 Zhao D Li Y Peng C Lin J Yu F Zhao Y Zhang X Zhao D. Outer membrane protein a in Acinetobacter baumannii induces autophagy through mTOR signalling pathways in the lung of SD rats . Biomed Pharmacother . 2021 Mar ; 135 : 111034 . https://doi.org/10.1016/j.biopha.2020.111034 Search in Google Scholar