<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3>
<p>This retrospective study investigated the efficacy of endovascular treatment with multilayer flow modulators (MFMs) for treating aortic aneurysms in high-risk patients unsuitable for conventional treatments.</p>
</sec>
<sec><h3>Patients and methods</h3>
<p>Conducted from 2011 to 2019 at a single center, this retrospective observational study included 17 patients who underwent endovascular treatment with MFMs. These patients were selected based on their unsuitability for traditional surgical or endovascular procedures. The study involved meticulous pre-procedural planning, precise implantation of MFMs, and follow-up using CT angiography. The primary focus was on volumetric and flow volume changes in aneurysms, along with traditional diameter measurements. Moreover, the technical success and post-procedural complications were also registered.</p>
</sec>
<sec><h3>Results</h3>
<p>The technical success rate was 100%, and 30-day procedural complication rate was 17.6%. Post-treatment assessments revealed that 11 out of 17 patients showed a decrease in flow volume within the aneurysm sac, indicative of a favorable hemodynamic response. The median decrease in flow volume was 12 ml, with a median relative decrease of 8%. However, there was no consistent reduction in aneurysm size; most aneurysms demonstrated a median increase in volume for 46 ml and median increase in diameter for 18 mm.</p>
</sec>
<sec><h3>Conclusions</h3>
<p>While MFMs offer a potential alternative for high-risk aortic aneurysm patients, their effectiveness in preventing aneurysm expansion is limited. The results suggest that MFMs can provide a stable hemodynamic environment but do not reliably reduce aneurysm size. This underscores the need for ongoing vigilance and long-term monitoring in patients treated with this technology.</p>
</sec>
</abstract>

Background
This retrospective study investigated the efficacy of endovascular treatment with multilayer flow modulators (MFMs) for treating aortic aneurysms in high-risk patients unsuitable for conventional treatments.

Patients and methods
Conducted from 2011 to 2019 at a single center, this retrospective observational study included 17 patients who underwent endovascular treatment with MFMs. These patients were selected based on their unsuitability for traditional surgical or endovascular procedures. The study involved meticulous pre-procedural planning, precise implantation of MFMs, and follow-up using CT angiography. The primary focus was on volumetric and flow volume changes in aneurysms, along with traditional diameter measurements. Moreover, the technical success and post-procedural complications were also registered.

Results
The technical success rate was 100%, and 30-day procedural complication rate was 17.6%. Post-treatment assessments revealed that 11 out of 17 patients showed a decrease in flow volume within the aneurysm sac, indicative of a favorable hemodynamic response. The median decrease in flow volume was 12 ml, with a median relative decrease of 8%. However, there was no consistent reduction in aneurysm size; most aneurysms demonstrated a median increase in volume for 46 ml and median increase in diameter for 18 mm.

Conclusions
While MFMs offer a potential alternative for high-risk aortic aneurysm patients, their effectiveness in preventing aneurysm expansion is limited. The results suggest that MFMs can provide a stable hemodynamic environment but do not reliably reduce aneurysm size. This underscores the need for ongoing vigilance and long-term monitoring in patients treated with this technology.

Long-term outcome of multilayer flow modulator in aortic aneurysms

Department of Radiology, Faculty of Medicine

Institute of Anatomy, Faculty of Medicine

Radiology and Oncology

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Long-term outcome of multilayer flow modulator in aortic aneurysms"}

Background
This retrospective study investigated the efficacy of endovascular treatment with multilayer flow modulators (MFMs) for treating aortic aneurysms in...

Long-term outcome of multilayer flow modulator in aortic aneurysms

Article Category: Research Paper

Online veröffentlicht: 14. Apr. 2024

Seitenbereich: -

Eingereicht: 12. Jan. 2024

Akzeptiert: 20. Feb. 2024

DOI: https://doi.org/10.2478/raon-2024-0021

Schlüsselwörter
multilayer flow modulator, aortic aneurism, long-term follow up, volumetric measurements

© 2024 Karlo Pintaric et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Long-term outcome of multilayer flow modulator in aortic aneurysms

Article Category: Research Paper

Online veröffentlicht: 14. Apr. 2024

Seitenbereich: -

Eingereicht: 12. Jan. 2024

Akzeptiert: 20. Feb. 2024

DOI: https://doi.org/10.2478/raon-2024-0021

Schlüsselwörtermultilayer flow modulator, aortic aneurism, long-term follow up, volumetric measurements

© 2024 Karlo Pintaric et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Schlüsselwörter
multilayer flow modulator, aortic aneurism, long-term follow up, volumetric measurements