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Pneumococcal pneumonia and invasive pneumococcal disease: immunopathogenesis and diagnosis

Gina Amanda

Gina Amanda

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan HospitalJakarta, Indonesia
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Amanda, Gina
, 
Dianiati Kusumo Sutoyo

Dianiati Kusumo Sutoyo

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan HospitalJakarta, Indonesia
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Sutoyo, Dianiati Kusumo
 und 
Erlina Burhan

Erlina Burhan

Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan HospitalJakarta, Indonesia
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Burhan, Erlina
  
02. Juli 2019
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Artikel-Kategorie: Reviews
Online veröffentlicht: 02. Juli 2019
Seitenbereich: 8 - 14
DOI: https://doi.org/10.2478/pneum-2019-0009
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© 2019 Amanda et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Virulence factors of S. pneumoniae. The figure is adapted with modification from Van der Poll T, Opal SM. Pathogenesis, treatment, and prevention of pneumococcal pneumonia. Lancet 2009;374(9700):1543-56. S. pneumoniae, Streptococcus pneumoniae.PsA = pneumococcal surface antigen A. PiaA/PiuA = pneumococcal iron acquisition and uptake. PspR = pneumococcal serine-rich repeat protein. PavA = pneumococcal adhesion and virulence. LTA = lipoteichoic acid.
Virulence factors of S. pneumoniae. The figure is adapted with modification from Van der Poll T, Opal SM. Pathogenesis, treatment, and prevention of pneumococcal pneumonia. Lancet 2009;374(9700):1543-56. S. pneumoniae, Streptococcus pneumoniae.PsA = pneumococcal surface antigen A. PiaA/PiuA = pneumococcal iron acquisition and uptake. PspR = pneumococcal serine-rich repeat protein. PavA = pneumococcal adhesion and virulence. LTA = lipoteichoic acid.

Figure 2

Mechanism of pneumococcal colonization in the respiratory tract. The figure is adapted with modification from Wyllie AL, Rümke LW, Arp K, Bosch AA, Bruin JP, Rots NY, et al. Molecular surveillance on Streptococcus pneumoniae carriage in non-elderly adults; little evidence for pneumococcal circulation independent from the reservoir in children. Sci Rep 2016;6:34888.
Mechanism of pneumococcal colonization in the respiratory tract. The figure is adapted with modification from Wyllie AL, Rümke LW, Arp K, Bosch AA, Bruin JP, Rots NY, et al. Molecular surveillance on Streptococcus pneumoniae carriage in non-elderly adults; little evidence for pneumococcal circulation independent from the reservoir in children. Sci Rep 2016;6:34888.

Figure 3

Mechanism of pneumococcal invasion from the respiratory tract to the bloodstream and CSF. The figure is adapted with modification from Wyllie AL, Rümke LW, Arp K, Bosch AA, Bruin JP, Rots NY, et al. Molecular surveillance on Streptococcus pneumoniae carriage in non-elderly adults; little evidence for pneumococcal circulation independent from the reservoir in children. Sci Rep 2016;6:34888. CSF, cerebrospinal fluid.
Mechanism of pneumococcal invasion from the respiratory tract to the bloodstream and CSF. The figure is adapted with modification from Wyllie AL, Rümke LW, Arp K, Bosch AA, Bruin JP, Rots NY, et al. Molecular surveillance on Streptococcus pneumoniae carriage in non-elderly adults; little evidence for pneumococcal circulation independent from the reservoir in children. Sci Rep 2016;6:34888. CSF, cerebrospinal fluid.
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Medizin, Klinische Medizin, Klinische Medizin, andere, Allgemeinmedizin, Innere Medizin, Pneumologie
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