Uneingeschränkter Zugang

Influence of inosine pranobex on cell viability in normal fibroblasts and liver cancer cells


Zitieren

Allen C.N., Harpur E.S., Gray T.J.B., Hirst B.H.: Toxic effects of non-steroidal anti-inflammatory drugs in a human intestinal epithelial cell line (HCT-8) as assessed by the MTT and neutral red assays. Toxicol In Vitro 1991, 5, 183–191.AllenC.N.HarpurE.S.GrayT.J.B.HirstB.H.Toxic effects of non-steroidal anti-inflammatory drugs in a human intestinal epithelial cell line (HCT-8) as assessed by the MTT and neutral red assaysToxicol In Vitro1991518319110.1016/0887-2333(91)90016-7Search in Google Scholar

Ballet J.J., Morin A., Schmitt C., Agrapart M.: Effect of isoprinosine on in vitro proliferative responses of human lymphocytes stimulated by antigen. Int J Immunopharmacol 1982, 4, 151–157.BalletJ.J.MorinA.SchmittC.AgrapartM.Effect of isoprinosine on in vitro proliferative responses of human lymphocytes stimulated by antigenInt J Immunopharmacol1982415115710.1016/0192-0561(82)90043-1Search in Google Scholar

Beken S., Kasper P., van der Laan J.W.: Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals. Adv Exp Med Biol. 2016, 856, 33–64.BekenS.KasperP.van derLaanJ.W.Regulatory acceptance of alternative methods in the development and approval of pharmaceuticalsAdv Exp Med Biol2016856336410.1007/978-3-319-33826-2_3Search in Google Scholar

Bopp S.K., Lettieri T.: Comparison of four different colourimetric and fluorometric cytotoxicity assays in a zebra fish liver cell line. BMC Pharmacol 2008, 8:8.BoppS.K.LettieriT.Comparison of four different colourimetric and fluorometric cytotoxicity assays in a zebra fish liver cell lineBMC Pharmacol20088:810.1186/1471-2210-8-8Search in Google Scholar

Borenfreund E., Babich H., Martin-Alguacil N.: Comparisons of two in vitro cytotoxicity assays–the neutral red (NR) and tetrazolium MTT tests. Toxicol In Vitro 1988, 2, 1–6.BorenfreundE.BabichH.Martin-AlguacilN.Comparisons of two in vitro cytotoxicity assays–the neutral red (NR) and tetrazolium MTT testsToxicol In Vitro198821610.1016/0887-2333(88)90030-6Search in Google Scholar

Chiba K., Kawakami K., Tohyama K.: Simultaneous evaluation of cell viability by neutral red, MTT and crystal violet staining assays of the same cells. Toxicol In Vitro 1998, 12, 251–258.ChibaK.KawakamiK.TohyamaK.Simultaneous evaluation of cell viability by neutral red, MTT and crystal violet staining assays of the same cellsToxicol In Vitro19981225125810.1016/S0887-2333(97)00107-0Search in Google Scholar

Edmondson J.M., Armstrong L.S., Martinez A.O.: A rapid and simple MTT-based spectro-photometric assay for determining drug sensitivity in monolayer cultures. J Tissue Cult Methods 1988, 11, 15–17.EdmondsonJ.M.ArmstrongL.S.MartinezA.O.A rapid and simple MTT-based spectro-photometric assay for determining drug sensitivity in monolayer culturesJ Tissue Cult Methods198811151710.1007/BF01404408Search in Google Scholar

Fotakis G., Timbrell J.A.: In vitro cytotoxicity assays: Comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride. Toxicol Lett 2006, 5, 160, 171–177.FotakisG.TimbrellJ.A.In vitro cytotoxicity assays: Comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chlorideToxicol Lett 2006516017117710.1016/j.toxlet.2005.07.001Search in Google Scholar

Gonzalez R.J., Tarloff J.B.: Evaluation of hepatic sub-cellular fractions for Alamar Blue and MTT reductase activity. Toxicol In Vitro 2001, 15, 257–259.GonzalezR.J.TarloffJ.B.Evaluation of hepatic sub-cellular fractions for Alamar Blue and MTT reductase activityToxicol In Vitro20011525725910.1016/S0887-2333(01)00014-5Search in Google Scholar

Hennessy K.J., Blecha F., Pollmann D.S., Kluber E.F.: Isoprinosine and levamisole immunomodulation in artificially reared neonatal pigs. Am J Vet Res 1987, 48, 477–480.HennessyK.J.BlechaF.PollmannD.S.KluberE.F.Isoprinosine and levamisole immunomodulation in artificially reared neonatal pigsAm J Vet Res198748477480Search in Google Scholar

Korting H.C., Schindler S., Hartinger A., Kerscher M., Angerpointner T., Maibach H.I.: MTT-assay and neutral red release (NRR)-assay: relative role in the prediction of the irritancy potential of surfactants. Proc Natl Sci Counc Repub China B 1994, 55, 533–540.KortingH.C.SchindlerS.HartingerA.KerscherM.AngerpointnerT.MaibachH.I.MTT-assay and neutral red release (NRR)-assay: relative role in the prediction of the irritancy potential of surfactantsProc Natl Sci Counc Repub China B19945553354010.1016/0024-3205(94)00746-2Search in Google Scholar

Korzeniewski C., Callewaert D.M.: An enzyme-release assay for natural cytotoxicity. J Immunol Methods 1983, 64, 313–320.KorzeniewskiC.CallewaertD.M.An enzyme-release assay for natural cytotoxicityJ Immunol Methods19836431332010.1016/0022-1759(83)90438-6Search in Google Scholar

Lasek W., Janyst M., Wolny R., Zapała Ł., Bocian K., Drela N.: Immuno-modulatory effects of inosine pranobex on cytokine production by human lymphocytes. Acta Pharm Jun 2015, 65, 171–180.LasekW.JanystM.WolnyR.Zapała ŁBocian K.DrelaN.Immuno-modulatory effects of inosine pranobex on cytokine production by human lymphocytesActa Pharm Jun20156517118010.1515/acph-2015-0015Search in Google Scholar

Lubet R.A., Kouri R.E., Curren R.A., Putman D.L., Schechtman L.M.: Induction of mutagenesis and transformation in BALB/c-3T3 clone A31-1 cells by diverse chemical carcinogens. Environ Mol Mutagen 1990, 16, 13–20.LubetR.A.KouriR.E.CurrenR.A.PutmanD.L.SchechtmanL.M.Induction of mutagenesis and transformation in BALB/c-3T3 clone A31-1 cells by diverse chemical carcinogensEnviron Mol Mutagen199016132010.1002/em.2850160103Search in Google Scholar

Majewska A., Lasek W., Janyst M., Młynarczyk G.: In vitro inhibition of HHV-1 replication by inosine pranobex and interferon- α. Acta Poloniae Pharmaceutica - Drug Res 2016, 73, 637–644.MajewskaA.LasekW.JanystM.MłynarczykG.In vitro inhibition of HHV-1 replication by inosine pranobex and interferon- αActa Poloniae Pharmaceutica - Drug Res201673637644Search in Google Scholar

Majewska A., Lasek W., Młynarczyk G.: Inosine pranobex - cytotoxic activities and effect of on replication of human para-influenza viruses (HPIV-2, HPIV-4), entroviruses (CA16, EV71) and adenoviruses (HAdV-2, HAdV-5) in vitro Med Dosw Mikrobiol 2015, 67, 107–113.MajewskaA.LasekW.MłynarczykG.Inosine pranobex - cytotoxic activities and effect of on replication of human para-influenza viruses (HPIV-2, HPIV-4), entroviruses (CA16, EV71) and adenoviruses (HAdV-2, HAdV-5) in vitroMed Dosw Mikrobiol201567107113Search in Google Scholar

Medicines & Healthcare products Regulatory Agency (MHRA), 2016. Patient leaflet: information for the user imunovir ® 500 mg tablets.Medicines & Healthcare products Regulatory Agency (MHRA), 2016. Patient leaflet: information for the user imunovir ® 500 mg tabletsSearch in Google Scholar

http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1476421779978.pdf.http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1476421779978.pdf.Search in Google Scholar

Morin A., Ballet J.J.: A recent review on in vitro and in vivo immunological activities of methisoprinol. Allergol Immunopathol 1982, 10, 109–114.MorinA.BalletJ.J.A recent review on in vitro and in vivo immunological activities of methisoprinolAllergol Immunopathol198210109114Search in Google Scholar

Mosmann T.: Rapid colourimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65, 55–63.MosmannT.Rapid colourimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assaysJ Immunol Methods198365556310.1016/0022-1759(83)90303-4Search in Google Scholar

NIEHS (National Institute of Environmental Health Sciences), Validation and Regulatory Acceptance of Toxicological Test Methods: A Report of the ad hoc Interagency Co-ordinating Committee on the Validation of Alternative Methods. NIH Publication No. 97-3981. https://ntp.niehs.nih.gov/iccvam/docs/about_docs/validate.pdf.NIEHS (National Institute of Environmental Health Sciences), Validation and Regulatory Acceptance of Toxicological Test Methods: A Report of the ad hoc Interagency Co-ordinating Committee on the Validation of Alternative Methods. NIH Publication No. 97-3981https://ntp.niehs.nih.gov/iccvam/docs/about_docs/validate.pdf.Search in Google Scholar

OECD, 2010. “Guidance Document on Using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systemic Toxicity Tests” OECD Guideline for the Testing of Chemicals, Guideline 129, 20 July 2010.OECD2010“Guidance Document on Using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systemic Toxicity Tests” OECD Guideline for the Testing of ChemicalsGuideline12920July 2010Search in Google Scholar

Olivier P., Testard P., Marzin D., Abbott D.: Effect of high polyol concentrations on the neutral red absorption assay and tetrazolium-MTT test of rat hepatocytes in primary culture. Toxicol In Vitro 1995, 9, 133–138.OlivierP.TestardP.MarzinD.AbbottD.Effect of high polyol concentrations on the neutral red absorption assay and tetrazolium-MTT test of rat hepatocytes in primary cultureToxicol In Vitro1995913313810.1016/0887-2333(94)00209-DSearch in Google Scholar

Petrova M., Jelev D., Ivanova A., Krastev Z.: Isoprinosine affects serum cytokine levels in healthy adults. J Interferon Cytokine Res 2010, 30, 223–228.PetrovaM.JelevD.IvanovaA.KrastevZ.Isoprinosine affects serum cytokine levels in healthy adultsJ Interferon Cytokine Res20103022322810.1089/jir.2009.0057Search in Google Scholar

Scheers E.M., Ekwall B., Dierickx P.J.,: In vitro long–term cytotoxicity testing of 27 MEIC chemicals on HepG2 cells and 220 comparison with acute human toxicity data. Toxicol In Vitro 15, 2001, 153–161.ScheersE.M.EkwallB.DierickxP.J.In vitro long–term cytotoxicity testing of 27 MEIC chemicals on HepG2 cells and 220 comparison with acute human toxicity dataToxicol In Vitro15200115316110.1016/S0887-2333(00)00062-XSearch in Google Scholar

Terpiłowska S., Siwicki A.K.: Interactions between chromium(III) and iron(III), molybdenum(III) or nickel(II): Cytotoxicity, genotoxicity and mutagenicity studies. Chemosphere 2018, doi: 10.1016/j.chemosphere.2018.03.062.TerpiłowskaS.SiwickiA.K.Interactions between chromium(III) and iron(III), molybdenum(III) or nickel(II): Cytotoxicity, genotoxicity and mutagenicity studiesChemosphere2018doi: 10.1016/j.chemosphere.2018.03.06210.1016/j.chemosphere.2018.03.062Search in Google Scholar

Triglia D., Braa S.S., Donnelly T., Kidd I.: A 3-dimensional human dermal model substrate for in vitro toxicological studies. In: Alternative Methods in Toxicology Edited by A.M. Goldberg, M.L. Principe. Mary Ann Liebert, New York, 1991, vol. 8, pp. 351–362.TrigliaD.BraaS.S.DonnellyT.KiddI.A 3-dimensional human dermal model substrate for in vitro toxicological studiesAlternative Methods in ToxicologyEdited by A.M. Goldberg, M.L. Principe. Mary Ann LiebertNew York1991vol. 8, pp351362Search in Google Scholar

Triglia D., Sherard Braa S., Yonan C., Naughton G.K.: Cytotoxicity testing using neutral red and MTT assays on a three-dimensional human skin substrate. Toxicol In Vitro 1991, 5, 573–578.TrigliaD.SherardBraa S.YonanC.NaughtonG.K.Cytotoxicity testing using neutral red and MTT assays on a three-dimensional human skin substrateToxicol In Vitro1991557357810.1016/0887-2333(91)90096-VSearch in Google Scholar

van de Sandt J.J.M., Rutten A.A.J.J.L., Koeeter H.B.W.M.: Cutaneous toxicity testing in organ culture: neutral red uptake and reduction of tetrazolium salt (MTT). Toxicol In Vitro 1993, 7, 81–86.vande Sandt J.J.M.RuttenA.A.J.J.L.KoeeterH.B.W.M.Cutaneous toxicity testing in organ culture: neutral red uptake and reduction of tetrazolium salt (MTT)Toxicol In Vitro19937818610.1016/0887-2333(93)90115-LSearch in Google Scholar

Vian L., Vincent J., Maurin J., Fabre I., Giroux J., Cano J.P.: Comparison of three in vitro cytotoxicity assays for estimating surfactant ocular irritation. Toxicol In Vitro 1995, 9, 185–190.VianL.VincentJ.MaurinJ.FabreI.GirouxJ.CanoJ.P.Comparison of three in vitro cytotoxicity assays for estimating surfactant ocular irritationToxicol In Vitro1995918519010.1016/0887-2333(94)00200-ESearch in Google Scholar

Wybran J., Faman J.P., Gortz R.: Inosiplex (Isoprinosine): a review of its immunological and clinical effects in disease. Adv Pharmacol Ther 1982, 6, 123–131.WybranJ.FamanJ.P.GortzR.Inosiplex (Isoprinosine): a review of its immunological and clinical effects in diseaseAdv Pharmacol Ther19826123131Search in Google Scholar

eISSN:
2450-8608
Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
4 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Biologie, Molekularbiologie, Mikrobiologie und Virologie, andere, Medizin, Veterinärmedizin