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In silico and in vitro conductivity models of the left heart ventricle

Leonie Korn

Leonie Korn

Medical Information Technology, RWTH Aachen UniversityAachen, Germany
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Korn, Leonie
, 
Simon Lyra

Simon Lyra

Medical Information Technology, RWTH Aachen UniversityAachen, Germany
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Lyra, Simon
, 
Daniel Rüschen

Daniel Rüschen

Medical Information Technology, RWTH Aachen UniversityAachen, Germany
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Rüschen, Daniel
, 
Dmitry Telyshev

Dmitry Telyshev

  • Institute for Biomedical Systems, National Research University of Electronic TechnologyMoscow, Russian Federation
  • Institute for Bionic Technologies and Engineering, I. M. Sechenov First MSMUMoscow, Russian Federation
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Telyshev, Dmitry
, 
Steffen Leonhardt

Steffen Leonhardt

Medical Information Technology, RWTH Aachen UniversityAachen, Germany
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Leonhardt, Steffen
 und 
Marian Walter

Marian Walter

Medical Information Technology, RWTH Aachen UniversityAachen, Germany
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Walter, Marian
  
26. Aug. 2020
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Online veröffentlicht: 26. Aug. 2020
Seitenbereich: 62 - 71
Eingereicht: 28. Mai 2020
DOI: https://doi.org/10.2478/joeb-2020-0010
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© 2020 Leonie Korn et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1

a) CAD model with the inner wax-/ polyvinylalcohol-core; b) 3D-printed casting molds from polylactide; c) Resulting insulating ventricle from silicone; d) Resulting conductive ventricle from silicone and carbon.
a) CAD model with the inner wax-/ polyvinylalcohol-core; b) 3D-printed casting molds from polylactide; c) Resulting insulating ventricle from silicone; d) Resulting conductive ventricle from silicone and carbon.

Fig. 2

Schematic overview of the modular layout of the impedance measurement unit.
Schematic overview of the modular layout of the impedance measurement unit.

Fig. 3

Left: In silico FE model similar to the in vitro model from CAD files; middle: Mesh view of the FE model; right: Close-up of the ventricle's longitudinal cross-section with the ten-electrode catheter.
Left: In silico FE model similar to the in vitro model from CAD files; middle: Mesh view of the FE model; right: Close-up of the ventricle's longitudinal cross-section with the ten-electrode catheter.

Fig. 4

Left: Measured impedances in the conductive (red) and insulating silicone ventricle (blue) impedance; right: Simulated impedances in the conductive (red) and insulating ventricle (blue).
Left: Measured impedances in the conductive (red) and insulating silicone ventricle (blue) impedance; right: Simulated impedances in the conductive (red) and insulating ventricle (blue).

Fig. 5

Close-up of the current paths in the ventricle with insulating properties (left) and conductive properties (right).
Close-up of the current paths in the ventricle with insulating properties (left) and conductive properties (right).

Calibration network consisting of four resistances used for the AFE4300_

R00 R01 R10 R11
14,9 Ω 46,97 Ω 679 Ω 995 Ω
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