N=71 patients | Time of presentation | Study inclusion (time 0) | p value* | 3rd hour | p value** |
---|---|---|---|---|---|
Heart rate b/min (SD) | # | 103.92 (18.67) | - | 98.7 (18.8) | 0.10 |
Systolic blood pressure mm Hg (SD) | 98 (22.5) | 118.0 (21.07) | <0.0001 | 122.7 (18.1) | 0.15 |
Diastolic blood pressure mm Hg (SD) | 49.5 (13.6) | 56.64 (13.13) | 0.0003 | 55.5 (11.8) | 0.60 |
Mean arterial blood pressure mm Hg (SD) | 64.6 (15) | 75.22 (13.69) | <0.0001 | 74.8 (11.6) | 0.86 |
Central venous pressure mm Hg (SD) | # | 7.34 (4.64) | - | 8.5 (4.7) | 0.13 |
CI l/min Mean (SD) | # | # | - | 3.5 (0.7) | - |
SVI Mean (SD) ml/m2/beat ) | # | # | - | 35.78 (10.7) | - |
SVRI Mean (SD) dynes-sec/cm–5/m2 | # | # | - | 1691.6 (630.06) | - |
GEDI Mean (SD) ml/kg | # | # | - | 647.5 (166.7) | - |
ITBI Mean (SD) ml/m2 | # | # | - | 829.7 (233.1) | - |
ELWI Mean (SD) Mean (SD) ml/kg | # | # | - | 8.75 (3.76) | - |
Norepinephrine mcg/kg/min | 0.07 (0.1) | 0.12 (0.15) | 0.01 | 0.11 (0.14) | 0.49 |
VDI | 0.11 (0.1) | 0.12 (0.15) | 0.03 | 0.16 (0.21) | 0.54 |
Creatinine mean (SD) μmol/l | # | 218.34 (192.7) | - | # | - |
Ureea mean (SD) mmol/l | # | 16.2 (12.1) | - | # | - |
lactate (septic shock patients) mmol/l (SD) | # | 3.93 (2.53) | - | 3.80 (3.03) | 0.30 |
oliguria/anuria no of patients (%) | # | 40 (56.3) | - | 28 (39.43) | 0.04 |
Capilary refill time >3 sec no of patients (%) | # | 17 (23.94)) | - | 12 (16.9) | 0.29 |
Diagnosis | N (%) |
---|---|
Sepsis | 37 (52.1%) |
Septic shock | 34 (47.9%) |
Type of sepsis | N (%) |
Medical | 26 (36.6%) |
Surgical | 45 (63.4%) |
Sex | N (%) |
Female | 21 (29.6%) |
Male | 50 (70.4%) |
Age Mean (SD) | 62.68 (14.78) |
Weight kg Mean (SD) | 82.58 (20.03) |
Body Surface Area Mean (SD) | 1.92 (0.24) |
Ventilation | N (%) |
Mechanically ventilated | 49 (69%) |
Spontaneous ventilation | 22 (31%) |
PEEP for Mechanically ventilated at study incluion (time 0) Mean (SD) | 5.69 (1.1) |
SOFA Score at study inclusion (time 0) Mean (SD) | 9.58 (3.27) |
Cardiovascular SOFA at study incluion (time 0) Mean (SD) | 2.85 (1.4) |
APACHE II Score at study incluion (time 0) Mean (SD) | 21.94 (8.64) |
Heart Rate at study incluion (time 0) Mean (SD) beats/min | 105.01 (20.64) |
Mean arterial blood pressure (MAP) at presentation Mean (SD) mm Hg | 64.6 (15.0) |
Lactate at study inclusion (time zero) mmol/l | 22.74 (20.25) |