Diagnostic Difficulties in a Severely Ill HIV Patient with Multiple Superinfections - A Case Report
Artikel-Kategorie: Case report
Online veröffentlicht: 27. Nov. 2019
Seitenbereich: 136 - 139
Eingereicht: 09. Aug. 2019
Akzeptiert: 31. Aug. 2019
DOI: https://doi.org/10.2478/jccm-2019-0020
Schlüsselwörter
© 2019 Cristina Mănășturean, Cristiana Oprea, Dan Oțelea, Anca Meda Georgescu, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
Introduction
As chronic HIV infection is prone to co-infections more than any other infectious condition, many severely immune-depressed patients require advanced diagnostic investigations and complex treatment.
Case report
The case of a 30-year-old severely immune-depressed patient with AIDS, who developed neurological impairment and was diagnosed with encephalitis is presented. Multiple diagnostic approaches had to be used in order to identify the etiologic agents responsible for the clinical, immunological and biological evolution. Despite using advanced laboratory investigations and complex treatment, the patient developed multiple organ dysfunction syndromes that led to a fatal outcome.
Conclusions
Establishing etiologic relations and treatment priorities in patients with severe immunodeficiency and co-infections can prove difficult, underlining the need of rapid syndromic testing.