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The Main Gaps for Randomized-controlled Trials in Psychiatry: A Bibliometric Study

João Mauricio Castaldelli-Maia
João Mauricio Castaldelli-Maia
, 
Michelle B. Riba
Michelle B. Riba
, 
Dusica Lecic-Tosevski
Dusica Lecic-Tosevski
, 
Prabha S. Chandra
Prabha S. Chandra
, 
Alfredo Cia
Alfredo Cia
, 
Peter J. Tyrer
Peter J. Tyrer
, 
Reinhard Heun
Reinhard Heun
 und 
Christopher Paul Szabo
Christopher Paul Szabo
   | 21. Mai 2020
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Online veröffentlicht: 21. Mai 2020
Seitenbereich: 51 - 63
Eingereicht: 21. Nov. 2019
Akzeptiert: 27. Feb. 2020
DOI: https://doi.org/10.2478/gp-2020-0008
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© 2020 João Mauricio Castaldelli-Maia et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Frequencies of numbers of randomized-controlled trials published in Pubmed per ICD-10 mental and behavioral chapter, in the last 20 years
Frequencies of numbers of randomized-controlled trials published in Pubmed per ICD-10 mental and behavioral chapter, in the last 20 years

Figure 2

Frequencies of numbers of randomized-controlled trials published in Pubmed per ICD-10 mental and behavioral chapter, in the last 20 years, in a logarithmic scale (y axis indicates the power to the basis 10)
Frequencies of numbers of randomized-controlled trials published in Pubmed per ICD-10 mental and behavioral chapter, in the last 20 years, in a logarithmic scale (y axis indicates the power to the basis 10)

Figure 3

Distribution of randomized-controlled trials published in Pubmed per top 20 ICD-10 mental and behavioral disorders, within different time frames.
Distribution of randomized-controlled trials published in Pubmed per top 20 ICD-10 mental and behavioral disorders, within different time frames.

Distribution of randomized-controlled trials (RCTs) published in Pubmed per ICD-10 mental and behavioral chapter in the last 20 years

1999–20032004–20082009–20132014–2018
ICD-10 Groupn%(+)Coef1Coef2 (95%CI)Coef3 (95%CI)n%(+)Coef1 (95%CI)Coef2Coef3 (95%CI)n%(+)Coef1 (95%CI)Coef2 (95%CI)Coef3n%(+)Coef1 (95%CI)Coef2 (95%CI)Coef3 (95%CI)
F00–F095414.2%Ref.66** (.20;1.12)Ref919.8%−.39* (−.77; −.01)RefRef22512.3%−.19 (−.53;.14).46** (.15;.77)Ref36714.9%−.01 (−.33;.32).81*** (.51;1.10)Ref
F10–F19359.2%Ref.73** (.20;1.25).18 (−.29;.66)555.8%−.46 (−.92;.00)Ref.11 (−.28;.51)1216.6%−.38 (−.79;.03).34 (−.02;.72)Ref1385.6%−.55** (−.95; −.14).33 (−.02;.70)−.35* (−.65; −.06)
F20–F295213.7%RefRef−.19 (−.61;.22)17018.1%.26 (−.09;.63)Ref.46** (.15;.77)26414.4%.01 (−.34;.34)RefRef30412.3%−.15 (−.49;.18)Ref−.34** (−.58; −.11)
F30–F3915139.6%Ref.26* (−.09;.63)−.19 (−.53;.14)37740.0%RefRef.19 (−.07;.47)76541.7%Ref.26* (.06;.49)Ref103341.8%Ref.42*** (.20;.64)−.18 (−.37;.00)
F40–F484612.1%Ref.35 (−.10;.42)−.24 (−.67;.19)10511.2%−.08 (−.48;.30)Ref.06 (−.27;.39)24413.3%.04 (−.31;.40).40** (.10;.70)Ref28811.7%−.08 (−.44;.26).42** (.13;.71)−.32** (−.56; −.08)
F50–F59359.2%Ref−.04 (−.53;.44)−.18 (−.65;.28)12012.7%.31 (−.10;.73)Ref.52** (.18;.85)1769.6%−.01 (−.41;.39)−.05 (−.35;.24)Ref30012.1%.22 (−.16;61).33* (.06;.61).04 (−.20;29)
F60–F6882.1%Ref.12 (−.73;.99)−.13 (−.94;.68)232.4%.14 (−.68;.96)Ref.40 (−.16;.97)382.1%−.06 (−.84;.71).06 (−.49;.61)Ref411.7%−.28 (−1.06;.48)−.01 (−.54;.54)−.41 (−.88;.05)
F70–F7900,0%N.A.N.A.N.A.10.1%N.A.N.A.N.A.00,0%N.A.N.A.N.A.00,00%N.A.N.A.N.A.
Groupn%(#)Coef4Coef5Coef6n%(#)Coef4Coef5Coef6n%(#)Coef4Coef5Coef6n%(#)Coef4Coef5Coef6
Mental3763.1%Ref−.41*** (−.53; −.29)−.56*** (−.67; −.45)9224.6%.41*** (.29;.53)Ref−.14*** (−.23; −.06)17705.3%.56*** (.45;.67).14*** (.06;.23)Ref23815.0%.51*** (.40;.62).09* (.01;.17)−.05 (−.11;.01)
Pubmed (Other)1187596.9%RefRefRef1919295.4%RefRefRef3173394.7%RefRefRef4503495.0%RefRefRef
%(+): Within the mental and behavioral chapter; %(#): Within entire Pubmed; (95%CI): 95% Confidence Interval
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