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Risk factors and care of early surgical site infection after primary posterior lumbar interbody fusion

Xiao-Lin Zuo
Xiao-Lin Zuo
 und 
Yan Wen
Yan Wen
   | 22. Juni 2023
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Article Category: Original Article
Online veröffentlicht: 22. Juni 2023
Seitenbereich: 203 - 211
Eingereicht: 30. Okt. 2022
Akzeptiert: 11. Dez. 2022
DOI: https://doi.org/10.2478/fon-2023-0021
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© 2023 Xiao-Lin Zuo et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.

Baseline data and univariate comparison between both groups

Variables SSI group (n = 18) Non-SSI group (n = 450) Statistical value P value OR 95% CI
Lower limit Upper limit
Gender (male/female) 5/13 242/208 χ2 = 3.922 0.047** 1.769 1.159 3.154
Age (years,x̄ ± s) 59.72 ± 7.19 56.34 ± 8.53 t = 2.472 0.012*** 2.106 1.267 4.171
ASA score (e.g., I/II/III) 9/7/2 192/238/20 Z = -0.774 0.452** 0.972 0.984 1.013
BMI (kg/m2) 23.92 ± 3.11 24.28 ± 3.21 t = 0.054 0.955* 1.001 0.998 1.005
Preoperative comorbidities
cardiovascular or cerebrovascular disease (e.g., yes/no) 2/16 33/417 χ2 = 0.216 0.635* 0.805 0.475 1.592
Diabetes (e.g., yes/no) 9/9 45/405 χ2 = 24.705 <0.001*** 1.035 1.127 1.225
Hypertension (e.g., yes/no) 4/14 76/374 χ2 = 0.060 0.805* 1.168 1.117 1.692
UTI (e.g., yes/no) 7/11 29/421 χ2 = 23.131 <0.001*** 1.006 1.002 1.021
Preoperative albumin (g/L) 36.12 ± 3.20 40.27 ± 3.08 t = –2.739 0.018*** 1.702 1.049 2.283
Preoperative hemoglobin (g/L) 134.27 ± 7.38 138.52 ± 8.59 t = –3.658 0.008*** 1.533 1.063 2.161
Operated level (e.g., single level/multiple levels) 5/13 289/161 χ2 = 13.621 <0.001*** 1.701 1.129 2.147
Operative time (min) 206.37 ± 15.58 181.15 ± 13.12 t = 8.515 <0.001*** 1.604 1.302 2.315
Intraoperative blood loss (mL) 262.24 ± 51.30 258.35 ± 49.06 0.320 0.731* 1.157 1.078 1.703
Intraoperative allogeneic blood transfusion (e.g., yes/no) 2/16 45/405 0.047 0.825* 1.021 1.019 1.475
Post-operative drainage (mL) 329.27 ± 53.69 291.52 ± 48.71 3.246 0.001*** 1.005 1.035 1.081
Post-operative draining time (d) 2.41 ± 0.45 2.02 ± 0.41 4.145 <0.001*** 1.028 1.205 2.039

Multivariate logistic regression analysis results for early SSI after PLIF.

Variables Regression coefficient Standard error P value OR 95% CI
Lower limit Upper limit
Gender –0.235 0.163 0.027 0.736 0.437 1.285
Preoperative diabetes 0.778 0.315 0.012 2.109 1.175 3.866
Preoperative UTI 0.510 0.162 0.035 1.526 1.008 2.869
Preoperative albumin –0.602 0.276 0.004 0.526 0.317 0.925
Time of draining 0.539 0.175 0.029 1.639 1.196 3.053
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