The High Penetrability of Nanoparticles into Bacterial Membranes: A Key of a Potential Application
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21. März 2023
Über diesen Artikel
Online veröffentlicht: 21. März 2023
Seitenbereich: 3 - 11
Eingereicht: 01. Jan. 2021
Akzeptiert: 01. Juni 2021
DOI: https://doi.org/10.2478/am-2023-0001
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© 2023 Amina Meliani et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Fig. 1
![Different actions of NPs in bacterial cells [1, 2, 3, 4]
With different size, shape, stiffness and surface charge NPs cross the bacterial membrane and disrupt cell membrane and wall, influencing several pathways. NPs trigger a generation of oxidative stress (ROS) that damage cellular proteins and cell’s basic components (DNA, ribosomes, enzymes), leading to changes in cell membrane permeability, metabolism pathways and biofilm disruption.](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6470930a71e4585e08aa03e2/j_am-2023-0001_fig_001.jpg?X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Credential=AKIA6AP2G7AKOUXAVR44%2F20250910%2Feu-central-1%2Fs3%2Faws4_request&X-Amz-Date=20250910T235338Z&X-Amz-Expires=3600&X-Amz-Signature=edd56f19ed61ee17dfbd816dc2c396c985966970c5e20dd65c6c2bf91b3e35f3&X-Amz-SignedHeaders=host&x-amz-checksum-mode=ENABLED&x-id=GetObject)