Diethylene glycol monoethyl ether-mediated nanostructured lipid carriers enhance trans-ferulic acid delivery by Caco-2 cells superior to solid lipid nanoparticles

1. Y. Liu, Z. Jiang, X. Hou, X. Xie, J. Shi, J. Shen, Y. He, Z. Wang and N. Feng, Functional lipid polymeric nanoparticles for oral drug delivery: Rapid mucus penetration and improved cell entry and cellular transport, Nanomedicine 21 (2019) Article ID 102075; https://doi.org/10.1016/j.nano.2019.10207531377378 Search in Google Scholar

2. J. Akbari, M. Saeedi, F. Ahmadi, S. M. H. Hashemi, A. Babaei, S. Yaddollahi, S. S. Rostamkalaei, K. Asare-Addo and A. Nokhodchi, Solid lipid nanoparticles and nanostructured lipid carriers: A review of the methods of manufacture and routes of administration, Pharm Dev. Technol. 27(5) (2022) 525–544; https://doi.org/10.1080/10837450.2022.208455435635506 Search in Google Scholar

3. Y. R. Neupane, M. D. Sabir, N. Ahmad, M. Ali and K. Kohli, Lipid drug conjugate nanoparticle as a novel lipid nanocarrier for the oral delivery of decitabine: ex vivo gut permeation studies, Nano-technology 24(41) (2013) Article ID 415102; https://doi.org/10.1088/0957-4484/24/41/41510224061410 Search in Google Scholar

4. Q. Xia, A. Saupe, R. H. Müller and E. B. Souto, Nanostrucured lipid carriers as novel carrier for sunscreen formulations, Int. J. Cosmet. Sci. 29(6) (2007) 473–482; https://doi.org/10.1111/j.1468-2494.2007.00410.x18489386 Search in Google Scholar

5. R. Augustine, A. A. Mamun, A. Hasan, S. A. Salam, R. Chandrasekaran, R. Ahmed and A. S. Thakor, Imaging cancer cells with nanostructures: Prospects of nanotechnology driven non-invasive cancer diagnosis, Adv. Colloid Interface Sci. 294 (2021) Article ID 102457; https://doi.org/10.1016/j.cis.2021.10245734144344 Search in Google Scholar

6. H. Liu, Z. Cai, F. Wang, L. Hong, L. Deng, J. Zhong, Z. Wang and W. Cui, Colon-targeted adhesive hydrogel microsphere for regulation of gut immunity and flora, Adv. Sci. (Weinheim) 8(18) (2021) e2101619 (12 pages); https://doi.org/10.1002/advs.202101619845627334292669 Search in Google Scholar

7. X. Zheng, C. Qiu, J. Long, A. Jiao, X. Xu, Z. Jin and J. Wang, Preparation and characterization of porous starch/beta-cyclodextrin microsphere for loading curcumin: Equilibrium, kinetics and mechanism of adsorption, Food Biosci. 41 (2021) Article ID 101081; https://doi.org/10.1016/j.fbio.2021.101081 Search in Google Scholar

8. M. Frühbauerová, L. Červenka, T. Hájek, M. Pouzar and J. Palarčík, Bioaccessibility of phenolics from carob (Ceratonia siliqua L.) pod powder prepared by cryogenic and vibratory grinding, Food Chem. 377 (2022) Article ID 131968; https://doi.org/10.1016/j.foodchem.2021.13196834995960 Search in Google Scholar

9. T. Peng, Y. Wang, T. Yang, F. Wang, J. Luo and Y. Zhang, Physiological and biochemical responses, and comparative transcriptome profiling of two Angelica sinensis cultivars under enhanced ultra-violet-B radiation, Front Plant. Sci. 12 (2021) Article ID 805407 (18 pages); https://doi.org/10.3389/fpls.2021.805407871892034975996 Search in Google Scholar

10. Y. Zhang, Z. Li, K. Zhang, G. Yang, Z. Wang, J. Zhao, R. Hu and N. Feng, Ethyl oleate-containing nanostructured lipid carriers improve oral bioavailability of trans-ferulic acid ascompared with conventional solid lipid nanoparticles, Int. J. Pharm. 511(1) (2016) 57–64; https://doi.org/10.1016/j.ijpharm.2016.06.13127374194 Search in Google Scholar

11. R. F. S. Gonçalves, J. T. Martins, L. Abrunhosa, J. Baixinho, A. A. Matias, A. A. Vicente and A. C. Pinheiro, Lipid-based nanostructures as a strategy to enhance curcumin bioaccessibility: Behavior under digestion and cytotoxicity assessment, Food Res. Int. 143 (2021) Article ID 110278; https://doi.org/10.1016/j.foodres.2021.11027833992378 Search in Google Scholar

12. E. T. Rodrigues, S. F. Nascimento, C. L. Pires, L. P. Godinho, C. Churro, M. J. Moreno and M. A. Pardal, Determination of intestinal absorption of the paralytic shellfish toxin GTX-5 using the Caco-2 human cell model, Environ. Sci. Pollut Res. Int. 28(47) (2021) 67256–67266; https://doi.org/10.1007/s11356-021-15342-y34247356 Search in Google Scholar

13. S. Youhanna and V. M. Lauschke, The past, present and future of intestinal in vitro cell systems for drug absorption studies, J. Pharm. Sci. 110(1) (2021) 50–65; https://doi.org10.1016/j.xphs.2020.07.00110.1016/j.xphs.2020.07.001 Search in Google Scholar

14. R. Hu, S. Liu, G. Anwaier, Q. Wang, W. Shen, Q. Shen and R. Qi, Formulation and intestinal absorption of naringenin loaded nanostructured lipid carrier and its inhibitory effects on nonalcoholic fatty liver disease, Nanomedicine 32 (2021) Article ID 102310; https://doi.org/10.1016/j.nano.2020.10231033184021 Search in Google Scholar

15. Q. Yu, X. Hu, Y. Ma, Y. Xie, Y. Lu, J. Qi, L. Xiang, F. Li and W. Wu, Lipids-based nanostructured lipid carriers (NLCs) for improved oral bioavailability of sirolimus, Drug Deliv. 23(4) (2016) 1469–1475; https://doi.org/10.3109/10717544.2016.115374427187522 Search in Google Scholar

16. J. Akbari, M. Saeedi, F. Ahmadi, S. Hashemi, A. Babaei, S. Yaddollahi, S. S. Rostamkalaei, K. Asare-Addo and A. Nokhodchi, Solid lipid nanoparticles and nanostructured lipid carriers: A review of the methods of manufacture and routes of administration, Pharm. Dev. Technol. 27(5) (2022) 525–544; https://doi.org/10.1080/10837450.2022.208455435635506 Search in Google Scholar

17. Z. Cheng, Y. Li, K. Wang, X. Zhu, P. Tharkar, W. Shu, T. Zhang, S. Zeng, L. Zhu, M. Murray, W. Chrzanowski and F. Zhou, Compritol solid lipid nanoparticle formulations enhance the protective effect of betulinic acid derivatives in human Müller cells against oxidative injury, Exp. Eye Res. 215 (2022) Article ID 108906; https://doi.org/10.1016/j.exer.2021.10890634953864 Search in Google Scholar

18. V. Pokharkar, A. Patil-Gadhe and G. Kaur, Physicochemical and pharmacokinetic evaluation of rosuvastatin loaded nanostructured lipid carriers: influence of long- and medium-chain fatty acid mixture, J. Pharm. Investig. 48 (2018) 465–476; https://doi.org/10.1007/s40005-017-0342-8 Search in Google Scholar

19. H. Shete, S. Chatterjee, A. De and V. Patravale, Long chain lipid based tamoxifen NLC. Part II: pharmacokinetic, biodistribution and in vitro anticancer efficacy studies, Int. J. Pharm. 454(1) (2013) 584–592; https://doi.org/10.1016/j.ijpharm.2013.03.03623535344 Search in Google Scholar

20. P. Ganesan, P. Ramalingam, G. Karthivashan, Y. T. Ko and D. K. Choi, Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in various chronic diseases, Int. J. Nanomedicine 13 (2018) 1569–1583; https://doi.org/10.2147/IJN.S155593585881929588585 Search in Google Scholar

21. M. Elmowafy, K. Shalaby, H. M. Ali, N. K. Alruwaili, A. Salama, M. F. Ibrahim, M. A. Akl and T. A. Ahmed, Impact of nanostructured lipid carriers on dapsone delivery to the skin: in vitro and in vivo studies, Int. J. Pharm. 572 (2019) Article ID 118781; https://doi.org/10.1016/j.ijpharm.2019.11878131715347 Search in Google Scholar

22. S. Haddadzadegan, F. Dorkoosh and A. Bernkop-Schnürch, Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers, Adv. Drug Deliv. Rev. 182 (2022) Article ID 114097 (26 pages); https://doi.org/10.1016/j.addr.2021.11409734999121 Search in Google Scholar

23. Y. Zhang, Z. Li, K. Zhang, G. Yang, Z. Wang, J. Zhao, R. Hu and N. Feng, Ethyl oleate-containing nanostructured lipid carriers improve oral bioavailability of trans-ferulic acid as compared with conventional solid lipid nanoparticles, Int. J. Pharm. 511(1) (2016) 57–64; https://doi.org/10.1016/j.ijpharm.2016.06.13127374194 Search in Google Scholar

24. L. Zhou, Y. Chen, Z. Zhang, J. He, M. Du and Q. Wu, Preparation of tripterine nanostructured lipid carriers and their absorption in rat intestine, Pharmazie 67(4) (2012) 304–310; https://doi.org/10.1691/ph.2012.1108 Search in Google Scholar

25. H. S. Rahman, A. Rasedee, H. H. Othman, M. S. Chartrand, F. Namvar, S. K. Yeap, N. Abdul Samad, R. J. Andas, N. Muhammad Nadzri, T. Anasamy, K. B. Ng and C. W. How, Acute toxicity study of zerumbone-loaded nanostructured lipid carrier on BALB/c mice model, Biomed. Res. Int. 2014 (2014) Article ID 563930 (15 pages); https://doi.org/10.1155/2014/563930417292425276798 Search in Google Scholar

26. J. Y. Fang, C. L. Fang, C. H. Liu and Y. H. Su, Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC), Eur. J. Pharm. Biopharm. 70(2) (2008) 633–640; https://doi.org/10.1016/j.ejpb.2008.05.00818577447 Search in Google Scholar

27. L. P. Mendes, J. M. F. Delgado, A. D. A. Costa, M. S. Vieira, P. L. Benfica, E. M. Lima and M. C. Valadares, Biodegradable nanoparticles designed for drug delivery: the number of nanoparticles impacts on cytotoxicity, Toxicol. in Vitro 29(6) (2015) 1268–1274; https://doi.org/10.1016/j.tiv.2014.12.02125596133 Search in Google Scholar

28. N. V. Shah, A. K. Seth, R. Balaraman, C. J. Aundhia, R. A. Maheshwari and G. R. Parmar, Nanostructured lipid carriers for oral bioavailability enhancement of raloxifene: Design and in vivo study, J. Adv. Res. 7(3) (2016) 423–434; https://doi.org/10.1016/j.jare.2016.03.002485683627222747 Search in Google Scholar

29. A. Beloqui, M. Á. Solinís, A. R. Gascón, A. del Pozo-Rodríguez, A. des Rieux and V. Préat, Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier, J. Control. Release 166(2) (2013) 115–123; https://doi.org/10.1016/j.jconrel.2012.12.02123266764 Search in Google Scholar

30. A. Ali Khan, J. Mudassir, N. Mohtar and Y. Darwis, Advanced drug delivery to the lymphatic system: lipid-based nanoformulations, Int. J. Nanomedicine 8(1) (2013) 2733–2744; https://doi.org/10.2147/IJN.S41521373220123926431 Search in Google Scholar

31. X. Zhou, X. Zhang, Y. Ye, T. Zhang, H. Wang, Z. Ma and B. Wu, Nanostructured lipid carriers used for oral delivery of oridonin: an effect of ligand modification on absorption, Int. J. Pharm. 479(2) (2015) 391–398; https://doi.org/10.1016/j.ijpharm.2014.12.06825556104 Search in Google Scholar

32. R. Ghadi and N. Dand, BCS class IV drugs: Highly notorious candidates for formulation development, J. Control. Release 248 (2017) 71–95; https://doi.org/10.1016/j.jconrel.2017.01.01428088572 Search in Google Scholar

33. V. Makwana, R. Jain, K. Patel, M. Nivsarkar and A. Joshi, Solid lipid nanoparticles (SLN) of efavirenz as lymph targeting drug delivery system: Elucidation of mechanism of uptake using chylomicron flow blocking approach, Int. J. Pharm. 495(1) (2015) 439–446; https://doi.org/10.1016/j.ijpharm.2015.09.01426367780 Search in Google Scholar