TLC-densitometric analysis of allantoin in Symphytum officinale L. roots

1. F. Stickel and H. K. Seitz, The efficacy and safety of comfrey, Public Health Nutr.3 (2000) 501–508; https://doi.org/10.1017/s136898000000058610.1017/S1368980000000586Search in Google Scholar

2. C. Staiger, Comfrey: A clinical overview, Phytother. Res.26 (2012) 1441–1448; https://doi.org/10.1002/ptr.461210.1002/ptr.4612349163322359388Search in Google Scholar

3. E. Neagu, G. P. Roman and G. L. Radu, Antioxidant capacity of some Symphytum officinalis extracts processed by ultrafiltration, Rom. Biotechnol. Lett.15 (2010) 5505–5511.Search in Google Scholar

4. L. U. Araújo, A. Grabe-Guimarães, V. C. F. Mosqueira, C. M. Carneiro and N. M. Silva-Barcellos, Profile of wound healing process induced by allantoin, Acta Cir. Bras.25 (2010) 460–461; https://doi.org/10.1590/s0102-8650201000050001410.1590/S0102-8650201000050001420877959Search in Google Scholar

5. G. Haghi, R. Arshi and A. Safaei, Improved high-performance liquid chromatography (HPLC) method for qualitative and quantitative analysis of allantoin in Zea mays, J. Agric. Food Chem.56 (2008) 1205–1209; https://doi.org/10.1021/jf072779310.1021/jf072779318189357Search in Google Scholar

6. Z. Maksimovic, A. Malenovic, B. Jancic and N. Kovacevic, Quantification of allantoin in various Zea mays L. hybrids by RP-HPLC with UV detection, Pharmazie59 (2004) 524–527; https://doi.org/10.1691/ph.2008.7394Search in Google Scholar

7. S.-J. Han and S.-N. Ryu, Quantitative analysis of allantoin in various rice varieties, J. Crop. Sci. Biotechnol.52 (2007) 453–457.Search in Google Scholar

8. S. Dresler, G. Szymczak and M. Wojcik, Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family, Pharm. Biol.55 (2017) 691–695; https://doi.org/10.1080/13880209.2016.126598610.1080/13880209.2016.1265986613057428140740Search in Google Scholar

9. J. Sherma and P. S. Cortelyou, Determination of allantoin in drug preparations by quantitative high-performance TLC, J. Liq. Chromatogr.9 (1986) 3415–3421; https://doi.org/10.1080/0148391860807779110.1080/01483918608077791Search in Google Scholar

10. M. Vlassa, M. Filip, V. Pascalau, V. Coman and C. Dragomir, Determination of purine derivatives in bovine urine using rapid chromatographic techniques, Arch. Zootech.12 (2009) 59–70.Search in Google Scholar

11. V. Barbakadze, K. Mulkijanyan, L. Gogilashvili, L. Amiranashvili, M. Merlani and Z. Novikova, Allantoin- and pyrrolizidine alkaloids-free wound healing compositions from Symphytum asperum, Bull. Georg. Natl. Acad. Sci.3 (2009) 159–164.Search in Google Scholar

12. Farmakopea Polska IX, Urząd Rejestracji Produktów Leczniczych, Wyrobów Medycznych i Produktów Biobójczych, Warszawa 2009.Search in Google Scholar

13. International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, ICH Harmonized Tripartite Guideline, Validation of Analytical Procedures: Text and Methodology Q2(R1), Current Step 4 version, Nov. 1996, Geneva, Nov. 2005; https://www.ich.org/products/guidelines/quality/article/quality-guidelines.html; last access date September 3, 2018.Search in Google Scholar

14. T. Doi, K. Kajimura, S. Takatori, N. Fukui, S. Taguchi and S. Iwagami, Simultaneous measurement of diazolidinyl urea, urea, and allantoin in cosmetic samples by hydrophilic interaction chromatography, J. Chromatogr. B877 (2009) 1005–1010; https://doi.org/10.1016/j.jchromb.2009.02.03210.1016/j.jchromb.2009.02.03219269905Search in Google Scholar

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