PRKAA2 variation and the clinical characteristics of patients newly diagnosed with type 2 diabetes mellitus in Yogyakarta, Indonesia
Dita Maria Virginia
- Department of Pharmacology and Therapy, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah MadaYogyakarta, Indonesia
- Faculty of Pharmacy, Universitas Sanata DharmaYogyakarta, Indonesia
Orcid-Profil, Mae Sri Hartati Wahyuningsih
Orcid-Profil und Dwi Aris Agung Nugrahaningsih
- Department of Pharmacology and Therapy, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah MadaYogyakarta, Indonesia
- Center of Genetic Study, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah MadaYogyakarta, Indonesia
Orcid-Profil 
Artikel-Kategorie: Original article
Online veröffentlicht: 20. Aug. 2021
Seitenbereich: 161 - 170
DOI: https://doi.org/10.2478/abm-2021-0021
Schlüsselwörter
© 2021 Dita Maria Virginia et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.
Background
Adenosine monophosphate (AMP)-activated protein kinase (AMPK; EC 2.7.11.31) enzymes play a pivotal role in cell metabolism. They are involved in type 2 diabetes mellitus (T2DM) pathogenesis. Genetic variation of
Objectives
To determine the association between
Methods
We performed a cross-sectional study including 166 T2DM patients from 10 primary health care centers in Yogyakarta, Indonesia. We measured fasting plasma glucose, hemoglobin A1c, serum creatinine, glomerular filtration rate, blood pressure, and body mass index as clinical characteristics.
Results
There was no difference in clinical characteristics for genotypes rs2796498, rs9803799, or rs2746342 (