Obstacles to diagnostic investigation of a child with comorbid psychiatric conditions
und | 15. Juni 2021
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Article Category: research-article
Online veröffentlicht: 15. Juni 2021
Seitenbereich: 105 - 112
DOI: https://doi.org/10.21307/sjcapp-2021-012
Schlüsselwörter
© 2021 Jena Salem et al., published by sciendo.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Diagnostic testing performed for investigation of autoimmune encephalitis
| Test | Source |
|---|---|
| vEEG with photic stimulation | N/A |
| Magnetic Resonance Imaging (MRI) | N/A |
| NDMA receptor antibody | Blood; CSF |
| Amino acid quantification | Blood; CSF |
| Bacterial culture, gram stain, glucose, protein, cell count | CSF |
| Immunoglobulin IgG index | Blood |
| Antinuclear antibody | Blood |
| Sjogren’s panel | Blood |
| Paraneoplastic panel | Blood |
| DNase antibody | Blood |
| Encephalopathy – autoimmune evaluation profile | Serum |
| Amino Acid Profile – quantitative | Blood; CSF |
| Antistreptolysin antibody | Blood |
| Pyruvate level | Blood; CSF |
| Lactate level | Blood; CSF |
| Enterovirus PCR | CSF |
| Varicella Zoster Virus – PCR | CSF |
| Herpes Simplex Virus – PCR | CSF |
| Lyme total antibody panel | CSF |
| Herpes Simplex Virus 1, 2 – IgG, IgM | CSF |
| Ebstein-Barr Virus – IgG, IgM | Blood |
| Lyme ELISA – IgG, IgM | Blood |
| Mycoplasma pneumonia – IgM | Blood |
| Mycoplasma pneumonia – PCR | Blood |
Schizophrenia diagnostic criteria – Elements of patient history
| Domain | Examples from patient presentation |
|---|---|
| Delusions | Paranoia delusions – religious repenting/guilt; food contamination |
| Hallucinations | Tactile hallucinations (bug on back) |
| Disorganized speech | Delayed/severely restricted/non-responsive speech, tangential speech |
| Grossly disorganized motor behavior | Catatonia, rigidity/immobility, posturing, echolalia |
| Negative symptoms | Decreased emotional expressions, flat affect |
Diagnostic testing performed for investigation of metabolic encephalopathy
| Test | Source |
|---|---|
| Copper level – 24 hr | Urine |
| Copper level | Blood |
| Cerulosplasmin level | Blood |
| Acylcarnitine profile | Blood |
| Pentacarboxyporphyrin | Urine |
| Porphobilinogen | Urine |
| Homocysteine | Blood |
| Heavy metals panel (arsenic, lead, mercury) | Blood |
| Serum drug screen (acetaminophen, salicylates, tri-cyclic antidepressants, ethyl alcohol) | Blood |