Primers | Sequences (5′<3′) | Amplicon Size |
---|---|---|
FGFR1-F | GAA GAC TGC TGG AGT TAA TAC C | 159 |
FGFR1-R | TCT TCC AGG GCT TCC AGA AC | |
FGFR3-F | CCA CTG TCT GGG TCA AGG AT | 180 |
FGFR3-R | AGG ATG GAG CGT CTG TCA C | |
GAPDH-F | ATC CTG GGC TAC ACT GAG C | 159 |
GAPDH-R | CAC CAC CCT GTT GCT GTA G |
Clinicopathological Parameters | % | |
---|---|---|
Age (years): | ||
≤66 | 26 | 52.0 |
>66 | 24 | 48.0 |
Sex: | ||
males | 43 | 86.0 |
females | 7 | 14.0 |
Stage: | ||
I | 16 | 32.0 |
II | 20 | 40.0 |
III | 10 | 20.0 |
IV | 4 | 8.0 |
Grade: | ||
low | 14 | 28.0 |
high | 36 | 72.0 |
Tumor type: | ||
non invasive muscle | 15 | 30.0 |
muscle invasive | 35 | 70.0 |
Family history: | ||
bladder cancer | 8 | 16.0 |
other cancer | 6 | 12.0 |
no cancer | 36 | 72.0 |
Smoker: | ||
≤10 | 2 | 4.0 |
>10 | 32 | 64.0 |
non smoker | 16 | 32.0 |
Occupational exposure | 27 | 54.0 |
Relative Expression | Variable(s) | Undersized Coefficients B | Standard Error B | ||
---|---|---|---|---|---|
FGFR1 | no significant variable | ||||
FGFR3 | (constant) family history of BC cigarette smoking | –28.908 | 11.031 | –2.621 | 0.021 |
14.266 | 4.125 | 3.458 | 0.004 | ||
11.568 | 4.968 | 2.329 | 0.037 |