Uneingeschränkter Zugang

Potassium channel inhibitors induce oxidative stress in breast cancer cells

Çağri Öner

Çağri Öner

Department of Medical Biology, Medical Faculty, Eskişehir Osmangazi UniversityEskişehir, Turkey
Suche nach diesem Autor auf
Sciendo|Google Scholar
Öner, Çağri
, 
Ertuğrul Çolak

Ertuğrul Çolak

Department of Biostatics and Bioinformatics, Medical Faculty, Eskişehir Osmangazi UniversityEskişehir, Turkey
Suche nach diesem Autor auf
Sciendo|Google Scholar
Çolak, Ertuğrul
 und 
Didem Turgut Coşan

Didem Turgut Coşan

Department of Medical Biology, Medical Faculty, Eskişehir Osmangazi UniversityEskişehir, Turkey
Suche nach diesem Autor auf
Sciendo|Google Scholar
Coşan, Didem Turgut
  
21. März 2018
Potassium channel inhibitors induce oxidative stress in breast cancer cells's Cover Image
Über diesen Artikel
Vorheriger Artikel
Nächster Artikel
Zitieren
COVER HERUNTERLADEN
Artikel-Kategorie: Original article
Online veröffentlicht: 21. März 2018
Seitenbereich: 323 - 330
DOI: https://doi.org/10.1515/abm-2018-0004
Schlüsselwörter
© 2017 Çağri Öner, Ertuğrul Çolak, Didem Turgut Coşan
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Figure 1

The effects of voltage-gated potassium channel inhibitors on the total antioxidant, oxidant, and oxidative stress levels of MCF-7 breast cancer cells. (A) The effects of tetraethyl ammonium chloride (TEA), 4-aminopyridine (4-AP), margatoxin (MgTX), or astemizole (AST) on the total antioxidant levels in MCF-7 cells. (B) The effects of TEA, 4-AP, MgTX, or AST on the total oxidant level in MCF-7 cells. (C) The effects of TEA, 4-AP, MgTX, or AST on the oxidative stress level in MCF-7 cells. n = 7 for each experiment group; error bars = 10 standard deviations. ∗P < 0.001
The effects of voltage-gated potassium channel inhibitors on the total antioxidant, oxidant, and oxidative stress levels of MCF-7 breast cancer cells. (A) The effects of tetraethyl ammonium chloride (TEA), 4-aminopyridine (4-AP), margatoxin (MgTX), or astemizole (AST) on the total antioxidant levels in MCF-7 cells. (B) The effects of TEA, 4-AP, MgTX, or AST on the total oxidant level in MCF-7 cells. (C) The effects of TEA, 4-AP, MgTX, or AST on the oxidative stress level in MCF-7 cells. n = 7 for each experiment group; error bars = 10 standard deviations. ∗P < 0.001

Figure 2

The effects of voltage-gated potassium channel inhibitors on the total antioxidant, oxidant and oxidative stress levels of MDA-MB-231 breast cancer cells. (A) The effects of tetraethyl ammonium chloride (TEA), 4-aminopyridine (4-AP), margatoxin (MgTX), and astemizole (AST) on the total antioxidant levels in MDA-MB-231 cells. (B) The effects of TEA, 4-AP, MgTX, and AST on the total oxidant level in MDA-MB-231 cells. (C) The effects of TEA, 4-AP, MgTX, and AST on the oxidative stress level of MDA-MB-231 cells. n = 7 for each experiment group; error bars = 10 standard deviations; ∗P < 0.001
The effects of voltage-gated potassium channel inhibitors on the total antioxidant, oxidant and oxidative stress levels of MDA-MB-231 breast cancer cells. (A) The effects of tetraethyl ammonium chloride (TEA), 4-aminopyridine (4-AP), margatoxin (MgTX), and astemizole (AST) on the total antioxidant levels in MDA-MB-231 cells. (B) The effects of TEA, 4-AP, MgTX, and AST on the total oxidant level in MDA-MB-231 cells. (C) The effects of TEA, 4-AP, MgTX, and AST on the oxidative stress level of MDA-MB-231 cells. n = 7 for each experiment group; error bars = 10 standard deviations; ∗P < 0.001
Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
6 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Medizin, Gesundheitsfachberufe, Vorklinische Medizin, Grundlagenmedizin, Vorklinische Medizin, Grundlagenmedizin, andere, Klinische Medizin, Klinische Medizin, andere
Zeitschrift RSS Feed