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Genetic Characterization of a Novel Composite Transposon Carrying armA and aac(6)-Ib Genes in an Escherichia coli Isolate from Egypt


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Bogaerts P., M. Galimand, C. Bauraing, A. Deplano, R. Vanhoof, R. De Mendonca, H. Rodriguez-Villalobos, M. Struelens and Y. Glupczynski. 2007. Emergence of ArmA and RmtB aminoglycoside resistance16S rRNA methylases in Belgium. J. Antimicrob. Chemother. 59: 459–464.10.1093/jac/dkl52717224412 Search in Google Scholar

Carattoli A. 2009. Resistance plasmid families in Enterobacteriaceae. Antimicrob. Agents Chemother. 53: 2227–2238.10.1128/AAC.01707-08268724919307361 Search in Google Scholar

Cattoir V., L. Poirel, V. Rotimi, C.J. Soussy and P. Nordmann. 2007. Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J. Antimicrob. Chemother. 60:394–397.10.1093/jac/dkm20417561500 Search in Google Scholar

Clinical and Laboratory Standards Institute (CLSI). 2012a. Performance standards for antimicrobial disk susceptibility tests, eleventh edition M02-A11. Clinical and Laboratory Standards Institute. Wayne, PA, USA. Search in Google Scholar

Clinical and Laboratory Standards Institute (CLSI). 2012b. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard ninth edition M07-A9. Clinical and Laboratory Standards Institute. Wayne, PA, USA. Search in Google Scholar

Dallenne C., A. Da Costa, D. Decré, C. Favier and G. Arlet. 2010. Development of a set of multiplex PCR assays for the detection of genes encoding important β-lactamases in Enterobacteriaceae. J. Antimicrob. Chemother. 65: 490–495.10.1093/jac/dkp49820071363 Search in Google Scholar

Davis M.A., K.N. Baker, L.H. Orfe, D.H. Shah, T.E. Besser and D.R. Call. 2010. Discovery of a gene conferring multiple-aminoglycoside resistance in Escherichia coli. Antimicrob. Agents Chemother. 54: 2666–2669.10.1128/AAC.01743-09287637220368404 Search in Google Scholar

Doi Y., K. Yokoyama, K. Yamane, J. Wachino, N. Shibata, T. Yagi, K. Shibayama, H. Kato and Y. Arakawa. 2004. Plasmid-mediated 16S rRNA methylase in Serratia marcescens conferring high-level resistance to aminoglycosides. Antimicrob. Agents Chemother. 48: 491–496.10.1128/AAC.48.2.491-496.200432155314742200 Search in Google Scholar

Doi Y. and Y. Arakawa. 2007. 16S Ribosomal RNA methylation: emerging resistance mechanism against Aminoglycosides. Clin. Infect. Dis. 45: 88–94.10.1086/51860517554708 Search in Google Scholar

Doi Y., D.O. Garcia, J. Adams and D.L. Paterson. 2007. Coproduction of novel 16S rRNA methylase RmtD and metallo-β-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. Antimicrob. Agents Chemother. 51: 852–856.10.1128/AAC.01345-06180310717158944 Search in Google Scholar

Fritsche T.R., M. Castanheira, G.H. Miller, R.N. Jones and E.S. Armstrong. 2008. Detection of methyltransferases conferring high-level resistance to aminoglycosides in Enterobacteriaceae from Europe, North America, and Latin America. Antimicrob. Agents Chemother. 52: 1843–1845.10.1128/AAC.01477-07234661718347105 Search in Google Scholar

Galani I., M. Souli, T. Panagea, G. Poulakou, K. Kanellakopoulou and H. Giamarellou. 2012. Prevalence of 16S rRNA methylase genes in Enterobacteriaceae isolates from a Greek University Hospital. Clin. Microbiol. Infect. 18: E52–E54.10.1111/j.1469-0691.2011.03738.x22264302 Search in Google Scholar

Galimand M., P. Courvalin and T. Lambert. 2003. Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob. Agents Chemother. 47: 2565–2571.10.1128/AAC.47.8.2565-2571.200316606512878520 Search in Google Scholar

Galimand M., S. Sabtcheva, P. Courvalin and T. Lambert. 2005. Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by composite transposon Tn1548. Antimicrob. Agents Chemother. 49: 2949–2953.10.1128/AAC.49.7.2949-2953.2005116863315980373 Search in Google Scholar

Galimand M., P. Courvalin and T. Lambert. 2012. RmtF, a new member of the aminoglycoside resistance 16S rRNA N7 G1405 methyltransferase family. Antimicrob. Agents Chemother. 56: 3960–3962. Search in Google Scholar

Gołebiewski. M., I. Kern-Zdanowicz, M. Zienkiewicz, M. Adamczyk, J. Zylinska, A. Baraniak, M. Gniadkowski, J. Bardowski and P. Cegłowski. 2007. Complete nucleotide sequence of the pCTX-M3 plasmid and its involvement in spread of the extended-spectrum β-lactamase gene blaCTX-M-3. Antimicrob. Agents Chemother. 51: 3789–3795.10.1128/AAC.00457-07215140817698626 Search in Google Scholar

González-Zorn B., A. Catalan, J.A. Escudero, L. Domínguez, T. Teshager, C. Porrero and M.A. Moreno. 2005a. Genetic basis for dissemination of armA. J. Antimicrob. Chemother. 56: 583–585.10.1093/jac/dki24616027145 Search in Google Scholar

González-Zorn B., T. Teshager, M. Casas, M.C. Porrero, M.A. Moreno, P. Courvalin and L. Domínguez. 2005b. armA and aminoglycoside resistance in Escherichia coli. Emerg. Infect. Dis. 11: 954–956.10.3201/eid1106.040553336760015963296 Search in Google Scholar

Granier S.A., L. Hidalgo, A. San Millan, J.A. Escudero, B. Gutierrez, A. Brisabois and B. Gonzalez-Zorn. 2011. ArmA methyltransferase in a monophasic Salmonella enteric isolate from food. Antimicrob. Agents Chemother. 55: 5262–5266.10.1128/AAC.00308-11319506221859937 Search in Google Scholar

Hassan A.M., O. Ibrahim and M. El Guinaidy. 2011. Surveillance of antibiotic use and resistance in orthopaedic department in an Egyptian University Hospital. Int. J. Infect. Control. 7: 1–10.10.3396/ijic.v7i1.006.11 Search in Google Scholar

Johnson T.J., Y.M. Wannemuehler, S.J. Johnson, C.M. Logue, D.G. White, C. Doetkott and L.K. Nolan. 2007. Plasmid replicon typing of commensal and pathogenic Escherichia coli isolates. Appl. Environ. Microbiol. 73:1976–1983.10.1128/AEM.02171-06182880917277222 Search in Google Scholar

Kang H.Y., K.Y. Kim, J. Kim, J.C. Lee, Y.C. Lee, D.T. Cho and S.Y. Seol. 2008. Distribution of conjugative-plasmid-mediated 16S rRNA methylase genes among amikacin-resistant Enterobacteriaceae isolates collected in 1995 to 1998 and 2001 to 2006 at a University Hospital in South Korea and identification of conjugative plasmids mediating dissemination of 16S rRNA Methylase. J. Clin. Microbiol. 46: 700–706.10.1128/JCM.01677-07223814318094126 Search in Google Scholar

Kashif M.T., A.S. Yassin and Ael-D. Hosny. 2012. Detection of AmpC beta-lactamases using sodium salicylate. J. Microbiol. Methods. 91: 354–357.10.1016/j.mimet.2012.09.03523059062 Search in Google Scholar

Lee H., D. Yong, J.H. Yum, K.H. Roh, K. Lee, K. Yamane, Y. Arakawa and Y. Chong. 2006. Dissemination of 16S rRNA methylase-mediated highly amikacin-resistant isolates of Klebsiella pneumoniae and Acinetobacter baumannii in Korea. Diagn. Microbiol. Infect. Dis. 56: 305–312.10.1016/j.diagmicrobio.2006.05.002 Search in Google Scholar

Magnet S. and J.S. Blanchard. 2005. Molecular insights into aminoglycoside action and resistance. Chem. Rev.105: 477–498.10.1021/cr0301088 Search in Google Scholar

Park C.H., A. Robicsek, G.A. Jacoby, D. Sahm and D.C Hooper. 2005. Prevalence in the United States of aac(6)-Ib-cr encoding a ciprofloxacin-modifying enzyme. Antimicrob. Agents Chemother. 50: 3953–3955.10.1128/AAC.00915-06 Search in Google Scholar

Poirel L., L. Dortet, S. Bernabeu and P. Nordmann. 2012. Genetic features of blaNDM-1-positive Enterobacteriaceae. Antimicrob. Agents Chemother. 55: 5403–5407.10.1128/AAC.00585-11 Search in Google Scholar

Wachinoa J. and Y. Arakawa. 2012. Exogenously acquired 16S rRNA methyltransferases found in aminoglycoside-resistant pathogenic Gram-negative bacteria: an update. Drug Resist. Updat. 15: 133–148.10.1016/j.drup.2012.05.001 Search in Google Scholar

Wachino J., K. Yamane, K. Shibayama, H. Kurokawa, N. Shibata, S. Suzuki, Y. Doi, K. Kimura, Y. Ike and Y. Arakawa. 2006. Novel plasmid-mediated 16S rRNA methylase, RmtC, found in a Proteus mirabilis isolate demonstrating extraordinary high-level resistance against various aminoglycosides. Antimicrob. Agents Chemother. 50: 178–184. Search in Google Scholar

World Health Organization (WHO). 2011. Critically important antimicrobials for human medicine, 2nd revision. World Health Organization. Geneva. http://apps.who.int/iris/bitstr eam/10665/77376/1/9789241504485_eng.pdf, 2015.02.20. Search in Google Scholar

Xia Q., H. Wang, A. Zhang, T. Wang and Y. Zhang. 2011. Prevalence of 16S rRNA methylase conferring high-level aminoglycoside resistance in Escherichia coli in China. Int. J. Antimicrob. Agents. 37: 385–388.10.1016/j.ijantimicag.2011.01.004 Search in Google Scholar

Yamane K., J. Wachino, S. Suzuki, N. Shibata, H. Kato, K. Shibayama, K. Kimura, K. Kai, S. Ishikawa, Y. Ozawa and others. 2007. 16S rRNA Methylase-producing, Gram-negative pathogens, Japan. Emerg. Infect. Dis. 13: 642–646.10.3201/eid1304.060501 Search in Google Scholar

Yamane K., J. Wachino, S. Suzuki and Y. Arakawa. 2008. Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. Antimicrob. Agents Chemother. 52: 1564–1566.10.1128/AAC.01137-07 Search in Google Scholar

Yang J., L. Ye, W. Wang, Y. Luo, Y. Zhang and L. Han. 2011. Diverse prevalence of 16S rRNA methylase genes armA and rmtB amongst clinical multidrug-resistant Escherichia coli and Klebsiella pneumoniae isolates. Int. J. Antimicrob. Agents. 38: 48–351.10.1016/j.ijantimicag.2011.04.021 Search in Google Scholar

Yokoyama K., Y. Doi, K. Yamane, H. Kurokawa, N. Shibata, K. Shibayama, T. Yagi, H. Kato and Y. Arakawa. 2003. Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa. Lancet 362: 1888–1893.10.1016/S0140-6736(03)14959-8 Search in Google Scholar

Zhang Y., H. Zhou, X.Q. Shen, P. Shen, Y.S. Yu and L.J. Li. 2008. Plasmid-borne armA methylase gene, together with blaCTX-M-15 and blaTEM-1, in a Klebsiella oxytoca isolate from China. J. Med. Microbiol. 57: 1273–1276.Search in Google Scholar

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