1. bookVolume 65 (2016): Issue 2 (June 2016)
Journal Details
License
Format
Journal
eISSN
2544-4646
First Published
04 Mar 1952
Publication timeframe
4 times per year
Languages
English
access type Open Access

Cytotoxic and Bacteriostatic Activity of Nanostructured TiO2 Coatings

Published Online: 07 Jun 2016
Volume & Issue: Volume 65 (2016) - Issue 2 (June 2016)
Page range: 225 - 229
Received: 09 Oct 2015
Accepted: 26 Nov 2015
Journal Details
License
Format
Journal
eISSN
2544-4646
First Published
04 Mar 1952
Publication timeframe
4 times per year
Languages
English
Abstract

Nanostructures are structures, mainly synthetic (nanosurfaces, cylindrical nanotubes, and nanospheres), which range between 1–100 nm in at least one dimension and can be engineered to a wide range of physical properties. This paper aims to explore the bacteriostatic and cytotoxic characteristics of nano-TiO2 coated specimens of glass, stainless steel and ceramic with different thickness and roughness. The results show that stainless steel and glass specimens with a nano-TiO2 coating thickness of 200 nm have a bacteriostatic effect of 97% and 100%, respectively after 30 minutes of UV exposure. Glass specimens with a nano-TiO2 coating thickness of 750, 200 and 50 nm have a bacteriostatic effect of 86%, 93% and 100% after 60 minutes. Nano-TiO2 coatings show a great bacteriostatic but not a cytotoxic effect, thus representing a valuable alternative for biomedical applications.

Keywords

Behzadnia A., M. Montazer and A. Rashidi. 2014. Rapid sonosynthesis of N-doped nano TiO2 on wool fabric at low temperature: introducing self-cleaning, hydrophilicity, antibacterial/antifungal properties with low alkali solubility, yellowness and cytotoxicity. Photochem Photobiol. 90: 1224–1233. Search in Google Scholar

Cai Y., M. Stromme and K. Welch. 2013. Photocatalytic antibacterial effects are maintained on resin-based TiO2 nanocomposites after cessation of UV irradiation. PLoS One 8: e75929.10.1371/journal.pone.0075929379831724146793 Search in Google Scholar

European Patent Application (EPA). EP 1 624 087 A1. Search in Google Scholar

Giolli C., F. Borgioli, A. Credi, A. Di Fabio, A. Fossati, M. Muniz Miranda, S. Parmeggiani, G. Rizzi, A. Scrivani, S. Troglio and others. 2007. Characterization of TiO2 coatings prepared by a modified electric arc-physical vapour deposition system. Surface & Coatings Technology 202: 13–22.10.1016/j.surfcoat.2007.04.043 Search in Google Scholar

He R., L. Zhao, Y. Liu, N. Zhang, B. Cheng, Z. He, B. Cai, S. Li, W. Liu, S. Guo and others. 2013. Biocompatible TiO2 nanoparticlebased cell immunoassay for circulating tumor cells capture and identification from cancer patients. Biomed. Microdevices 15: 617–626.10.1007/s10544-013-9781-923780622 Search in Google Scholar

Kepenek, B., U.O.S. Seker and A.F. Cakir. 2004. Photocatalalytic bactericidal effect of TiO2 thin film produced by Cathodic Arc Deposition Method. Key Engineering Materials 254–256: 463–466.10.4028/www.scientific.net/KEM.254-256.463 Search in Google Scholar

Khataee R., V. Heydari and L. Moradkhannejhad. 2013. Selfcleaning and mechanical properties of modified white cement with nanostructured TiO2. J. Nanosci. Nanotechnol. 13: 5109–51014.10.1166/jnn.2013.758623901537 Search in Google Scholar

Kho Y.K., A. Iwase and W.Y. Teoh. 2010. Photocatalytic H2 evolution over TiO2 nanoparticles. The synergistic effect of anatase and rutile. J. Phys. Chem. C. 114: 2821–2829.10.1021/jp910810r Search in Google Scholar

Kulkarni M., A. Mazare and E. Gongadze. 2015. Titanium nanostructures for biomedical applications. Nanotechnology 26: 062002.10.1088/0957-4484/26/6/06200225611515 Search in Google Scholar

Lee K., A. Mazare and P. Schmuki. 2014. One-dimensional titanium dioxide nanomaterials: nanotubes. Chem. Rev. 114: 9385–9454.10.1021/cr500061m25121734 Search in Google Scholar

Li G., N.M. Dimitrijevic and L. Chen. 2008. The important role of tetrahedral Ti4+ sites in the phase transformation and photocatalytic activity of TiO2 nanocomposites. J. Am. Chem. Soc. 130: 5402–5403.10.1021/ja711118u18370389 Search in Google Scholar

Liao Y., W. Que and Q. Jia. 2012. Controllable synthesis of brookite/anatase/rutile TiO2 nanocomposites and single-crystalline rutile nanorods array. J. Mater. Chem. 22: 7937–7944.10.1039/c2jm16628c Search in Google Scholar

Mikkelsen L., M. Sheykhzade and K.A. Jensen. 2011. Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO(2). Part Fibre Toxicol. 8: 32.10.1186/1743-8977-8-32324542822074227 Search in Google Scholar

Petrini P., C.R. Arciola and I. Pezzali. 2006. Antibacterial activity of zinc modified titanium oxide surface. Int. J. Artif. Organs 29: 434–442.10.1177/03913988060290041416705613 Search in Google Scholar

Pleskova S.N., I.S. Golubeva and I. Verevkin. 2011. Photoinduced bactericidal activity of TiO2 films. Prikl. Biokhim. Mikrobiol. 47: 28–32.10.1134/S0003683811010091 Search in Google Scholar

Roy P., S. Berger and P. Schmuki. 2011. TiO2 nanotubes: synthesis and applications. Angew. Chem. Int. Ed. Engl. 50: 2904–2939.10.1002/anie.20100137421394857 Search in Google Scholar

Seo J.W., H. Chung and M.Y. Kim. 2007. Development of watersoluble single-crystalline TiO2 nanoparticles for photocatalytic cancer-cell treatment. Small 3: 850–853.10.1002/smll.20060048817385208 Search in Google Scholar

Tao T., Y. Chen and D. Zhou. 2013. Expanding the applications of the ilmenite mineral to the preparation of nanostructures: TiO2 nanorods and their photocatalytic properties in the degradation of oxalic acid. Chemistry 19: 1091–1096.10.1002/chem.20120245123180682 Search in Google Scholar

Wang Y., Y. He. and Q. Lai. 2014. Review of the progress in preparing nano TiO2: an important environmental engineering material. J. Environ. Sci. (China) 26: 2139–2177.10.1016/j.jes.2014.09.02325458670 Search in Google Scholar

Xi B., L.K. Verma and J. Li. 2012. TiO2 thin films prepared via adsorptive self-assembly for self-cleaning applications. ACS Appl. Mater. Interfaces. 4: 1093–10102.10.1021/am201721e22260264 Search in Google Scholar

Yu B., W. M. Lau and J. Yang. 2013. Preparation and characterization of N-TiO2 photocatalyst with high crystallinity and enhanced photocatalytic inactivation of bacteria. Nanotechnology 24: 335705.10.1088/0957-4484/24/33/33570523892455 Search in Google Scholar

Zuo X., J. Hu. and M. Chen. 2015. The role and fate of inorganic nitrogen species during UVA/TiO disinfection. Water Res. 80: 12–19.10.1016/j.watres.2015.05.01825989592 Search in Google Scholar

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