Incidence and outcomes of acute lung injury in the surgical intensive care unit of a tertiary care hospital in Bangkok, Thailand
, , , , , and | Jan 31, 2017
About this article
Article Category: Brief communication (Original)
Published Online: Jan 31, 2017
Page range: 379 - 385
DOI: https://doi.org/10.5372/1905-7415.1004.501
Keywords
© 2016 Onuma Chaiwat, Worawan Suwannasri, Jedsadayoot Sak-aroonchai, Sawita Kanavitoon, Annop Piriyapathsom, Chainida Sirisatjawat, Nusara Kulana
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Figure 1
Ventilatory support data presented as N (%) and mean ± SD
| No ALI/ARDS (n = 464) | ALI/ARDS (n = 15) | 95%CI | ||
|---|---|---|---|---|
| Mode of MV of day 1 | ||||
| CMV | 290 (63%) | 9 (60%) | 0.79 | |
| SIMV | 150 (32%) | 6 (40%) | ||
| Mode of MV of day 2 (n = 426) | ||||
| CMV | 177 (42%) | 8/15 (53%) | 0.38 | |
| SIMV | 173 (40%) | 7/15 (47%) | ||
| Maximal tidal volume (mL) | ||||
| Day 1 | 504.6 ± 101.4 | 441.2 ± 85.2 | 0.02 | 11.3, 115.4 |
| Day 2 | 494.6 ± 94.4 | 483.7 ± 115.5 | 0.70 | –38.3, 60.0 |
| Maximal tidal volume per kg of PBW | ||||
| Day 1 | 9.3 ± 2.0 | 7.7 ± 1 . 6 | 0.003 | 0.6, 2.6 |
| Day 2 | 9.2 ± 1.9 | 8.5 ± 2 . 0 | 0.16 | –0.3, 1.6 |
| Maximal PEEP level (cmH2O) | ||||
| Day 1 | 5.1 ± 1.3 | 5.5 ± 1 . 2 | 0.25 | –1.0, 0.3 |
| Day 2 | 5.3 ± 1.6 | 6.8 ± 2 . 0 | 0.008 | –2.3, -0.7 |
Comparison of data between ALI/ARDS and non-ALI/ARDS groups. Data presented as n (%), mean ± standard deviation, and median (interquartile range).
| No ALI/ARDS (n = 464) | ALI/ARDS (n = 15) | 95% CI | ||
|---|---|---|---|---|
| Age | 64.6 ± 16.6 | 66.3 ± 17.7 | 0.69 | –10.3, 6.8 |
| Sex: male | 251 (54%) | 12 (80%) | 0.06 | 0.08, 1.1 |
| Weight (kg) | 60.4 ± 14.0 | 60.7 ± 13.9 | 0.94 | –7.5, 6.9 |
| Height (cm) | 160.1 ± 7.9 | 162.5 ± 10.3 | 0.25 | –6.5, 1.7 |
| Body mass index | 23.5 ± 5.0 | 22.7 ± 3.3 | 0.54 | –1.6, 3.4 |
| Ethnicity: Thai | 458 (99%) | 14 (93%) | 0.20 | 0.6, 48.4 |
| ASA >2 | 362 (78%) | 13 (87%) | 0.54 | 0.4, 8.2 |
| Functional class >2 | 50 (11%) | 3 (20%) | 0.22 | 0.6, 7.6 |
| Smoking | 27 (6%) | 1 (7%) | 0.60 | 0.1, 9.1 |
| Medical history | ||||
| Cardiovascular | 250 (54%) | 9 (60%) | 0.79 | 0.5, 3.7 |
| Diabetes | 114 (25%) | 4 (27%) | 0.77 | 0.4, 3.6 |
| Cerebrovascular | 40 (9%) | 1 (7%) | 1.00 | 0.1, 5.9 |
| Vascular | 38 (8%) | 2 (13%) | 0.36 | 0.4, 7.9 |
| Respiratory | 38 (8%) | 0 (0%) | 0.62 | |
| End-stage renal disease | 28 (6%) | 4 (27%) | 0.01 | 1.7, 18.9 |
| APACHE II score | 13.6 ± 6.6 | 19.4 ± 8 . 8 | 0.001 | –9.2, -2.4 |
| Type of SICU admission | ||||
| No surgery | 102 (28%) | 7 (47%) | 0.05 | 0.1, 0.9 |
| After surgery | 362 (78%) | 8 (53%) | ||
| Emergency or unplanned admission | 318/444 (72%) | 12/14 (86%) | 0.37 | 0.5, 10.8 |
| Hb at SICU admission | 10.4 ± 2.1 | 9.9 ± 2 . 2 | 0.35 | –0.6, 1.7 |
| Albumin at SICU admission | 2.6 ± 0.7 | 2.2 ± 0 . 7 | 0.09 | –0.05, 0.7 |
| Sepsis at SICU admission | 158 (34%) | 9 (60%) | 0.05 | 1.0, 8.3 |
| Balance fluid at 24 h | 1,593 (538, 2,832) | 2,368 (1,450, 5,299) | 0.08 | |
| Total red blood cell count (mL) | 644 (344, 1,048) | 1,069 (729, 1,613) | 0.03 | |
| Total FFP (mL) | 939 (467, 1,461) | 2,344 (1,248, 4,865) | 0.06 |
Organ dysfunction and outcomes, data presented as n (%)
| No ALI/ARDS (n = 464) | ALI/ARDS (n = 15) | 95% CI | ||
|---|---|---|---|---|
| ARF | 48 (10%) | 5 (33%) | 0.02 | 1.4, 13.2 |
| Pneumonia | 42 (9%) | 6 (40%) | 0.002 | 2.3, 19.7 |
| Sepsis | 39 (8%) | 3 (20%) | 0.14 | 0.7, 10.0 |
| Shock | 25 (5%) | 2 (13%) | 0.20 | 0.6, 12.6 |
| GI bleeding | 21 (5%) | 0 | >0.999 | |
| Myocardial ischemia | 9 (2%) | 0 | >0.999 | |
| Outcomes | ||||
| Duration of MV (day) | 5 (3, 12) | 17 (6, 22) | 0.002 | –14.4, 2.8 |
| ICU LOS (day) | 7 (4, 13) | 20 (6, 28) | 0.01 | –13.7, 2.0 |
| Hospital LOS (day) | 26 (15, 49) | 22 (8, 39) | 0.30 | –16.1, 18.0 |
| 30-day mortality | 99 (21%) | 7 (47%) | 0.03 | 1.1, 9.1 |
| Hospital mortality | 109 (24%) | 9 (60%) | 0.003 | 1.7, 14.0 |