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Fibroglandular tissue and quantitative background parenchymal enhancement on magnetic resonance breast images are inversely correlated with menopause in Thai women

Anchukorn Rijiravanich
Anchukorn Rijiravanich
 and 
Jatuporn Chayakulkheeree
Jatuporn Chayakulkheeree
   | Jan 31, 2017
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Article Category: Brief communication (Original)
Published Online: Jan 31, 2017
Page range: 519 - 526
DOI: https://doi.org/10.5372/1905-7415.0904.422
Keywords
© 2015 Anchukorn Rijiravanich, Jatuporn Chayakulkheeree
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

A: Nonenhanced axial T1-weighted magnetic resonance images with fat saturation and B: contrast-enhanced subtraction from a 49-year-old premenopausal woman demonstrate extremely dense fibroglandular tissue and marked background parenchymal enhancement. C: Time (x-axis) after intravenous contrast administration versus percentage enhancement (y-axis) reveals a gradually increased enhancement (type 1 pattern), Eearly = 28%, Epeak = 102%.
A: Nonenhanced axial T1-weighted magnetic resonance images with fat saturation and B: contrast-enhanced subtraction from a 49-year-old premenopausal woman demonstrate extremely dense fibroglandular tissue and marked background parenchymal enhancement. C: Time (x-axis) after intravenous contrast administration versus percentage enhancement (y-axis) reveals a gradually increased enhancement (type 1 pattern), Eearly = 28%, Epeak = 102%.

Figure 2

A: Nonenhanced axial T1-weighted magnetic resonance images with fat saturation and B: contrast-enhanced subtraction from a 53-year-old postmenopausal woman demonstrate almost entirely fatty breast and minimal background parenchymal enhancement. C: Time (x-axis) after intravenous contrast administration versus percentage enhancement (y-axis) reveals gradually increased enhancement (type 1 pattern), Eearly = 7%, Epeak = 22%.
A: Nonenhanced axial T1-weighted magnetic resonance images with fat saturation and B: contrast-enhanced subtraction from a 53-year-old postmenopausal woman demonstrate almost entirely fatty breast and minimal background parenchymal enhancement. C: Time (x-axis) after intravenous contrast administration versus percentage enhancement (y-axis) reveals gradually increased enhancement (type 1 pattern), Eearly = 7%, Epeak = 22%.

Figure 3

A:Nonenhanced axial T1-weighted magnetic resonance images with fat saturation and B: contrast-enhanced subtraction from a 34-year-old premenopausal woman demonstrates heterogeneously dense fibroglandular tissue and minimal background parenchymal enhancement. Images C and D are from a 62-year-old postmenopausal woman, demonstrating scattered fibroglandular tissue and moderate parenchymal enhancement.
A:Nonenhanced axial T1-weighted magnetic resonance images with fat saturation and B: contrast-enhanced subtraction from a 34-year-old premenopausal woman demonstrates heterogeneously dense fibroglandular tissue and minimal background parenchymal enhancement. Images C and D are from a 62-year-old postmenopausal woman, demonstrating scattered fibroglandular tissue and moderate parenchymal enhancement.

Correlation between magnetic resonance imaging fibroglandular tissue and background parenchymal enhancement (BPE), including the visually assessed BPE classified according to the American College of Radiology Breast Imaging Reporting and Data System 2013 and quantitative enhancement kinetics including the enhancement at 90 seconds (Eearly), at 6 minutes (Epeak), and signal enhancement ratio (SER).

BPEEearlyEearlySER
Spearman ρFibroglandular tissue
Correlation coefficient0.1790.0020.103–0.116
Significance (2-tailed)0.0830.9850.3220.265
N95959595

Comparison of magnetic resonance imaging fibroglandular tissue (FGT), visually assessed background parenchymal enhancement (BPE), enhancement at 90 s (Eearly), enhancement at 6 min (Epeak), and signal enhancement ratio (SER) between pre and postmenopausal women.

FGTBPEEearlyEpeakSER
Mann–Whitney U243270430369538.5
Wilcoxon W3564359137513690.643.5
Z–3.6-3.4–1.5–2.1–0.3
Asymp significance (2-tailed)0.0000.0010.150.040.77

Description of the 95 normal breast magnetic resonance imaging analyses by visually assessment of fibroglandular tissue and background parenchymal enhancement classified according to the American College of Radiology Breast Imaging Reporting and Data System 2013

Menopausal statusBackground parenchymal enhancementTotal
MinimalMildModerateMarked
Postmenopause
Fibroglandular tissue
 Almost entirely fat820010
 Scattered11114026
 Heterogeneous15174036
 Extreme61209
Total403110081
Premenopause
 Fibroglandular tissue
 Heterogeneous05128
 Extreme13026
Total181414
eISSN:
1875-855X
Language:
English
Publication timeframe:
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Journal Subjects:
Medicine, Assistive Professions, Nursing, Basic Medical Science, other, Clinical Medicine
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