<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p><bold>Background.</bold> One of the major challenges in cancer therapy is to improve early detection and prevention using novel targeted cancer diagnostics. Detection requests specific recognition. Tumor markers have to be ideally present on the surface of cancer cells. Their targeting with ligands coupled to imaging agents make them visible/detectable.</p><p><bold>Conclusions.</bold> Fluorescence imaging is a newly emerging technology which is becoming a complementary medical method for cancer diagnosis. It allows detection with a high spatio-temporal resolution of tumor markers in small animals and in clinical studies. In this review, we focus on the recent outcome of basic studies in the design of new approaches (probes and devices) used to detect tumor cells by fluorescence imaging.</p></abstract>

Background. One of the major challenges in cancer therapy is to improve early detection and prevention using novel targeted cancer diagnostics. Detection requests specific recognition. Tumor markers have to be ideally present on the surface of cancer cells. Their targeting with ligands coupled to imaging agents make them visible/detectable.Conclusions. Fluorescence imaging is a newly emerging technology which is becoming a complementary medical method for cancer diagnosis. It allows detection with a high spatio-temporal resolution of tumor markers in small animals and in clinical studies. In this review, we focus on the recent outcome of basic studies in the design of new approaches (probes and devices) used to detect tumor cells by fluorescence imaging.

Fluorescence imaging agents in cancerology

CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), Toulouse, France

UPS, IPBS, Université de Toulouse, Toulouse, France

Radiology and Oncology

{"article-title":"Fluorescence imaging agents in cancerology"}

Background. One of the major challenges in cancer therapy is to improve early detection and prevention using novel targeted cancer diagnostics. Detection...

Fluorescence imaging agents in cancerology

Published Online: Jun 16, 2010

Page range: 142 - 148

DOI: https://doi.org/10.2478/v10019-010-0031-y

Keywords
Photonic imaging, fluorescence, cancerology, apramers, smart probes

This content is open access.

Fluorescence imaging agents in cancerology

Published Online: Jun 16, 2010

Page range: 142 - 148

DOI: https://doi.org/10.2478/v10019-010-0031-y

KeywordsPhotonic imaging, fluorescence, cancerology, apramers, smart probes

This content is open access.

Keywords
Photonic imaging, fluorescence, cancerology, apramers, smart probes