<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Hexane, chloroform, ethyl acetate and ethanolic extracts of the aerial parts of <italic>Centaurea austro-anatolica</italic> Hub.-Mor. (<italic>Asteraceae</italic>) were evaluated against microorganisms, including multiresistant bacteria, using a paper disc diffusion method. The chloroform extract exhibited significant antibacterial activity toward all bacteria tested. The chemical composition of the chloroform extract was determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The major compounds of the extract were caryophyllene oxide (21.32 %), spathulenol (10.86 %), <italic>n</italic>-tricosanol (9.58 %) and geranyl isovalerate (8.71 %).</p></abstract>

Hexane, chloroform, ethyl acetate and ethanolic extracts of the aerial parts of Centaurea austro-anatolica Hub.-Mor. (Asteraceae) were evaluated against microorganisms, including multiresistant bacteria, using a paper disc diffusion method. The chloroform extract exhibited significant antibacterial activity toward all bacteria tested. The chemical composition of the chloroform extract was determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The major compounds of the extract were caryophyllene oxide (21.32 %), spathulenol (10.86 %), n-tricosanol (9.58 %) and geranyl isovalerate (8.71 %).

Chemical composition of endemic <italic>Centaurea austro-anatolica</italic> and studies of its antimicrobial activity against multi-resistant bacteria

Department of Biology, Faculty of Arts and Sciences, Mugla University, 48121 Kotekli-Mugla, Turkey

Medical Laboratory Program Vocational School of Health Services, Mugla University, 48700 Marmaris-Mugla, Turkey

Department of Nursing Health College, Usak University, 64100 Usak, Turkey

Department of Chemistry Faculty of Arts and Sciences, Mugla University, 48121 Kotekli-Mugla, Turkey

Acta Pharmaceutica

Chemical composition of endemic  and studies of its antimicrobial activity against multi-resistant bacteria

Hexane, chloroform, ethyl acetate and ethanolic extracts of the aerial parts of Centaurea austro-anatolica Hub.-Mor. (Asteraceae) were evaluated against...

Chemical composition of endemic Centaurea austro-anatolica and studies of its antimicrobial activity against multi-resistant bacteria

Published Online: Nov 16, 2009

Page range: 463 - 472

DOI: https://doi.org/10.2478/v10007-009-0036-5

Keywords
kemijski sastav, antimikrobno djelovanje

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