Gradient HPLC analysis of raloxifene hydrochloride and its application to drug quality control
Published Online: Dec 22, 2008
Page range: 347 - 356
DOI: https://doi.org/10.2478/v10007-008-0018-z
Keywords
This content is open access.
A rapid, sensitive and selective method for the determination of raloxifene hydrochloride (RLX) in pure drug and in tablets was developed using gradient high performance liquid chromatography (HPLC). The devised method involved separation of RLX on a reversed phase Hypersil ODS column and determination with UV detection at 284 nm. The standard curve was linear (