<abstract xmlns="http://www.w3.org/1999/xhtml"><sec><h3>Introduction</h3><p>The two primary objectives of this paper were (a) to develop first logically consistent TTO based EQ-5D-3L value sets for Slovenia and (b) to revisit earlier developed VAS based EQ-5D-3L value sets.</p></sec><sec><h3>Methods</h3><p>Between September 2005 and April 2006, face-to-face interviews with 225 individuals in Slovenia were conducted. Protocols from the Measurement and Value of Health study were followed closely. Each respondent valued 15 health states out of a total of 23. Model selection was informed by the criteria monotonicity/logical consistency. Predictive accuracy was assessed in terms of mean square difference between out-of-sample predictions and corresponding observed means, as well as Lin’s Concordance Correlation Coefficient.</p></sec><sec><h3>Results</h3><p>Modelling was based on 2,717 VAS and 2,831 TTO values elicited from 225 respondents. A 6-parameter constrained regression model with a supplementary power term was selected for VAS and TTO value sets, as it produces monotonic values, and proved superior in terms of out-of-sample predictive accuracy over the tested alternatives.</p></sec><sec><h3>Conclusion</h3><p>This is the first EQ-5D-3L TTO based value set in Slovenia and the second in Central and Eastern Europe (besides Poland). It is also the first monotonic and logically consistent VAS value set in Central and Eastern Europe. Comparisons with Polish and UK TTO values show considerable differences, mostly due to mobility with having a substantially greater weight in Slovenia. The UK value set generally produces lower values and the Polish value set higher values for mild states.</p></sec></abstract>

IntroductionThe two primary objectives of this paper were (a) to develop first logically consistent TTO based EQ-5D-3L value sets for Slovenia and (b) to revisit earlier developed VAS based EQ-5D-3L value sets.MethodsBetween September 2005 and April 2006, face-to-face interviews with 225 individuals in Slovenia were conducted. Protocols from the Measurement and Value of Health study were followed closely. Each respondent valued 15 health states out of a total of 23. Model selection was informed by the criteria monotonicity/logical consistency. Predictive accuracy was assessed in terms of mean square difference between out-of-sample predictions and corresponding observed means, as well as Lin’s Concordance Correlation Coefficient.ResultsModelling was based on 2,717 VAS and 2,831 TTO values elicited from 225 respondents. A 6-parameter constrained regression model with a supplementary power term was selected for VAS and TTO value sets, as it produces monotonic values, and proved superior in terms of out-of-sample predictive accuracy over the tested alternatives.ConclusionThis is the first EQ-5D-3L TTO based value set in Slovenia and the second in Central and Eastern Europe (besides Poland). It is also the first monotonic and logically consistent VAS value set in Central and Eastern Europe. Comparisons with Polish and UK TTO values show considerable differences, mostly due to mobility with having a substantially greater weight in Slovenia. The UK value set generally produces lower values and the Polish value set higher values for mild states.

Valuation of EQ-5D-3l Health States in Slovenia: VAS based and TTO based Value Sets

Slovenian Journal of Public Health

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Vrednotenje Zdravstvenih stanj EQ-5D-3l V Sloveniji: Vrednosti Zdravstvenih stanj, Pridobljene Z Metodama VAS in TTO

IntroductionThe two primary objectives of this paper were (a) to develop first logically consistent TTO based EQ-5D-3L value sets for Slovenia and (b) to...

Valuation of EQ-5D-3l Health States in Slovenia: VAS based and TTO based Value Sets

Article Category: Original scientific article

Published Online: Dec 13, 2019

Page range: 8 - 17

Received: May 21, 2019

Accepted: Sep 26, 2019

DOI: https://doi.org/10.2478/sjph-2020-0002

Keywords
EQ-5D-3L, Slovenia, quality-adjusted life-years, social value set, utility

© 2020 Valentina Prevolnik Rupel et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Valuation of EQ-5D-3l Health States in Slovenia: VAS based and TTO based Value Sets

Article Category: Original scientific article

Published Online: Dec 13, 2019

Page range: 8 - 17

Received: May 21, 2019

Accepted: Sep 26, 2019

DOI: https://doi.org/10.2478/sjph-2020-0002

KeywordsEQ-5D-3L, Slovenia, quality-adjusted life-years, social value set, utility

© 2020 Valentina Prevolnik Rupel et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
EQ-5D-3L, Slovenia, quality-adjusted life-years, social value set, utility