<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Cylindrospermopsin (CYN) is a cytotoxin produced by several species of cyanobacteria, which occur all over the world. It was demonstrated that CYN has a wide spectrum of biological activity in animal cells, involving hepatotoxicity, genotoxicity, cytotoxicity and carcinogenic potential, and is considered as one of the factors that caused human poisoning in Palm Island (Australia) and in Caruaru (Brazil). This compound may be introduced into organism by several ways, including consumption of water, fishes and seafood as well as accidental swallowing or aerosol spray inhalation during recreational using of reservoirs covered by cyanobacterial blooms. The information about the CYN impact on environment and its degradation processes under natural conditions is scant. Taking this into consideration CYN should be regarded as a potential threat to human health and life. This review presents physicochemical characteristic and biological activity of CYN, occurrence in freshwaters and its sensitivity to the influence of some environmental factors.</p>
</abstract>

Cylindrospermopsin (CYN) is a cytotoxin produced by several species of cyanobacteria, which occur all over the world. It was demonstrated that CYN has a wide spectrum of biological activity in animal cells, involving hepatotoxicity, genotoxicity, cytotoxicity and carcinogenic potential, and is considered as one of the factors that caused human poisoning in Palm Island (Australia) and in Caruaru (Brazil). This compound may be introduced into organism by several ways, including consumption of water, fishes and seafood as well as accidental swallowing or aerosol spray inhalation during recreational using of reservoirs covered by cyanobacterial blooms. The information about the CYN impact on environment and its degradation processes under natural conditions is scant. Taking this into consideration CYN should be regarded as a potential threat to human health and life. This review presents physicochemical characteristic and biological activity of CYN, occurrence in freshwaters and its sensitivity to the influence of some environmental factors.

Cylindrospermopsin: cyanobacterial secondary metabolite. Biological aspects and potential risk for human health and life

Department of Plant Physiology and Development

Oceanological and Hydrobiological Studies

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Cylindrospermopsin (CYN) is a cytotoxin produced by several species of cyanobacteria, which occur all over the world. It was demonstrated that CYN has a wide...

Cylindrospermopsin: cyanobacterial secondary metabolite. Biological aspects and potential risk for human health and life

Published Online: Jan 04, 2015

Page range: 442 - 449

DOI: https://doi.org/10.2478/s13545-014-0148-5

Keywords
cyanobacteria, cylindrospermopsin, biological activity, natural degradation, toxicity

© 2014 Faculty of Oceanography and Geography, University of Gdańsk, Poland

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Cylindrospermopsin: cyanobacterial secondary metabolite. Biological aspects and potential risk for human health and life

Published Online: Jan 04, 2015

Page range: 442 - 449

DOI: https://doi.org/10.2478/s13545-014-0148-5

Keywordscyanobacteria, cylindrospermopsin, biological activity, natural degradation, toxicity

© 2014 Faculty of Oceanography and Geography, University of Gdańsk, Poland

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
cyanobacteria, cylindrospermopsin, biological activity, natural degradation, toxicity