Open Access

Value of serum NT-IGFBP-4 for non-invasive risk stratification of coronary heart disease and predictive efficiency for complexity of coronary artery lesions

, , , ,  and   
Aug 06, 2025

Cite
Download Cover

Duggan JP, Peters AS, Trachiotis GD, Antevil JL. Epidemiology of Coronary Artery Disease. Surg Clin North Am. 2022;102(3):499-516. DOI: 10.1016/j.suc.2022.01.007 Search in Google Scholar

Shaya GE, Leucker TM, Jones SR, Martin SS, Toth PP. Coronary heart disease risk: Low-density lipoprotein and beyond. Trends Cardiovasc Med. 2022;32(4):181-94. DOI: 10.1016/j.tcm.2021.04.002 Search in Google Scholar

Mortensen MB, Dzaye O, Bøtker HE, Jensen JM, Maeng M, Bentzon JF, et al. Low-Density Lipoprotein Cholesterol Is Predominantly Associated With Atherosclerotic Cardiovascular Disease Events in Patients With Evidence of Coronary Atherosclerosis: The Western Denmark Heart Registry. Circulation. 2023;147(14):1053-63. DOI: 10.1161/CIRCULATIONAHA.122.061010 Search in Google Scholar

Kwiecinski J, Tzolos E, Williams MC, Dey D, Berman D, Slomka P, et al. Noninvasive Coronary Atherosclerotic Plaque Imaging. JACC Cardiovasc Imaging. 2023;16(12):1608-22. DOI: 10.1016/j.jcmg.2023.08.021 Search in Google Scholar

In China TWCOTROCHAD, Hu SS. Report on cardiovascular health and diseases in China 2021: an updated summary. J Geriatr Cardiol. 2023;20(6):399-430. DOI: 10.26599/1671-5411.2023.06.001 Search in Google Scholar

Yang T, Liu Y, Li L, Zheng Y, Wang Y, Su J, et al. Correlation between the triglyceride-to-high-density lipoprotein cholesterol ratio and other unconventional lipid parameters with the risk of prediabetes and Type 2 diabetes in patients with coronary heart disease: a RCSCD-TCM study in China. Cardiovasc Diabetol. 2022;21(1):93. DOI: 10.1186/s12933-022-01531-7 Search in Google Scholar

Lu X, Liu Z, Cui Q, Liu F, Li J, Niu X, et al. A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. Eur Heart J. 2022;43(18):1702-11. DOI: 10.1093/eurheartj/ehac093 Search in Google Scholar

Adasheva DA, Lebedeva OS, Goliusova DV, Postnikov AB, Teriakova MV, Kopylova IV, et al. PAPP-A-specific IGFBP-4 proteolysis in human induced pluripotent stem cell-derived cardiomyocytes. Int J Mol Sci. 2023;24(9):8420. DOI: 10.3390/ijms24098420 Search in Google Scholar

Hjortebjerg R, Lindberg S, Pedersen S, Mogelvang R, Jensen JS, Oxvig C, et al. Insulin-like growth factor binding protein 4 fragments provide incremental prognostic information on cardiovascular events in patients with ST-segment elevation myocardial infarction. J Am Heart Assoc. 2017;6(3):e005358. DOI: 10.1161/JAHA.116.005358 Search in Google Scholar

Ndrepepa G. SYNTAX Score and Outcomes in Complex Coronary Artery Disease After Percutaneous Coronary Intervention: Is the Use of Intravascular Ultrasound an Equalizer of Disease Severity? Am J Cardiol. 2023;206:345-6. DOI: 10.1016/j.amjcard.2023.08.150 Search in Google Scholar

Serruys PW, Revaiah PC. Leveraging QFR and SYNTAX score II 2020 to guide PCI versus CABG decisions in multivessel CAD -broadening QFR’s utility. EuroIntervention. 2024;20(9):518-20. DOI: 10.4244/EIJ-E-24-00024 Search in Google Scholar

Guo J, Wang H, Li Y, Zhu S, Hu H, Gu Z. Nanotechnology in coronary heart disease. Acta Biomater. 2023;171:37-67. DOI: 10.1016/j.actbio.2023.09.011 Search in Google Scholar

Shaikh A, Khan SD, Baloch F, Virani SS, Samad Z. The COVID-19 Pandemic and Coronary Heart Disease: the Next Surge. Curr Atheroscler Rep. 2023;25(9):559-69. DOI: 10.1007/s11883-023-01131-0 Search in Google Scholar

Boakye E, Grandhi GR, Dardari Z, Adhikari R, Soroosh G, Jha K, et al. Cardiovascular risk stratification among individuals with obesity: The Coronary Artery Calcium Consortium. Obesity. 2023;31(9):2240-8. DOI: 10.1002/oby.23832 Search in Google Scholar

Awasthi S, Sachdeva N, Gupta Y, Anto AG, Asfahan S, Abbou R, et al. Identification and risk stratification of coronary disease by artificial intelligence-enabled ECG. EClinicalMedicine. 2023;65:102259. DOI: 10.1016/j.eclinm.2023.102259 Search in Google Scholar

Razavi AC, Uddin SMI, Dardari ZA, Berman DS, Budoff MJ, Miedema MD, et al. Coronary Artery Calcium for Risk Stratification of Sudden Cardiac Death: The Coronary Artery Calcium Consortium. JACC Cardiovasc Imaging. 2022;15(7):1259-70. DOI: 10.1016/j.jcmg.2022.02.011 Search in Google Scholar

Scala A, Erriquez A, Verardi FM, Marrone A, Scollo E, Trichilo M, et al. Functional (Re)Development of SYNTAX Score II 2020: Predictive Performance and Risk Assessment. J Clin Med. 2023;12(18):5844. DOI: 10.3390/jcm12185844 Search in Google Scholar

Etman W, Loutfi M, Ahmed K, Eltahan S, Rayan A. Outcome of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Patients With Intermediate SYNTAX II Score. Curr Probl Cardiol. 2023;48(2):101512. DOI: 10.1016/j.cpcardiol.2022.101512 Search in Google Scholar

Medranda GA, Faraz HA, Thompson JB, Zhang Y, Bharadwaj AS, Osborn EA, et al. Association of Preprocedural SYNTAX Score With Outcomes in Impella-Assisted High-Risk Percutaneous Coronary Intervention. J Soc Cardiovasc Angiogr Interv. 2024;3(8):101981. DOI: 10.1016/j.jscai.2024.101981 Search in Google Scholar

Bhattarai A, Singh Sunar P, Shah S, Chamlagain R, Babu Pokhrel N, Khanal P, et al. CT-IGFBP-4 as a Predictive Novel Biomarker of Ischemic Cardiovascular Events and Mortality: A Systematic Review. J Interv Cardiol. 2022;2022:1816504. DOI: 10.1155/2022/1816504 Search in Google Scholar

Kageyama S, Serruys PW, Kotoku N, Garg S, Ninomiya K, Masuda S, et al. Coronary computed tomography angiography-based SYNTAX score for comprehensive assessment of advanced coronary artery disease. J Cardiovasc Comput Tomogr. 2024;18(2):120-36. DOI: 10.1016/j.jcct.2023.10.012 Search in Google Scholar

Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Life Sciences, Molecular Biology, Biochemistry, Human Biology, Microbiology and Virology