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In-situ coronary thrombosis without atherosclerosis in a young male: A case of multifactorial thrombophilia

Vasilyeva Larisa Ivanovna

Ivanovna, Vasilyeva Larisa

and

Kalashnikova Oksana Sergeevna

Sergeevna, Kalashnikova Oksana

Sep 12, 2025

In-situ coronary thrombosis without atherosclerosis in a young male: A case of multifactorial thrombophilia's Cover Image

Romanian Journal of Cardiology

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Article Category: Original Article

Published Online: Sep 12, 2025

DOI: https://doi.org/10.2478/rjc-2025-0024

Keywords
myocardial infarction, in-situ thrombosis, antiphospholipid syndrome, thrombophilia, COVID-19, young adults, genetic risk

© 2024 Vasilyeva Larisa Ivanovna et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Electrocardiogram. QS complex in V1, absence of R-wave progression in V2–V4, ST depression in leads II, III, and aVF.

Angiogram of the left coronary artery. Coronary angiography (12 hours post-symptom onset) revealed a mural thrombus in the proximal left anterior descending artery (LAD) with TIMI III flow and no signs of atherosclerosis, dissection, or vasospasm.

Angiogram of the right coronary artery. The right coronary artery is normal.

Electrocardiogram (discharge). Persistent QS complex in V1–V2, minimal R-wave in V3 (1 mm), no positive dynamics in V4, confirming completed transmural Q-wave MI.

Language:: English

Publication timeframe:: 4 times per year
Journal Subjects:: Medicine, Clinical Medicine, Internal Medicine, Cardiology, Surgery, Cardiac Surgery, Pediatrics and Juvenile Medicine, Paediatric Cardiology

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