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KRAS, NRAS, BRAF, HER2 and microsatellite instability in metastatic colorectal cancer – practical implications for the clinician

Vlad-Adrian Afrăsânie

Vlad-Adrian Afrăsânie

  • “Gr. T. Popa” University of Medicine and Pharmacy IașiIași, Romania
  • Regional Institute of Oncology IașiIași, Romania
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Afrăsânie, Vlad-Adrian
, 
Mihai Vasile Marinca

Mihai Vasile Marinca

  • “Gr. T. Popa” University of Medicine and Pharmacy IașiIași, Romania
  • Regional Institute of Oncology IașiIași, Romania
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Marinca, Mihai Vasile
, 
Teodora Alexa-Stratulat

Teodora Alexa-Stratulat

  • “Gr. T. Popa” University of Medicine and Pharmacy IașiIași, Romania
  • Regional Institute of Oncology IașiIași, Romania
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Alexa-Stratulat, Teodora
, 
Bogdan Gafton

Bogdan Gafton

  • “Gr. T. Popa” University of Medicine and Pharmacy IașiIași, Romania
  • Regional Institute of Oncology IașiIași, Romania
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Gafton, Bogdan
, 
Marius Păduraru

Marius Păduraru

  • “Gr. T. Popa” University of Medicine and Pharmacy IașiIași, Romania
  • Regional Institute of Oncology IașiIași, Romania
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Păduraru, Marius
, 
Anca Maria Adavidoaiei

Anca Maria Adavidoaiei

“Gr. T. Popa” University of Medicine and Pharmacy IașiIași, Romania
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Adavidoaiei, Anca Maria
, 
Lucian Miron

Lucian Miron

  • “Gr. T. Popa” University of Medicine and Pharmacy IașiIași, Romania
  • Regional Institute of Oncology IașiIași, Romania
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Miron, Lucian
 and 
Cristina Rusu

Cristina Rusu

“Gr. T. Popa” University of Medicine and Pharmacy IașiIași, Romania
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Rusu, Cristina
  
Sep 24, 2019
KRAS, NRAS, BRAF, HER2 and microsatellite instability in metastatic colorectal cancer – practical implications for the clinician's Cover Image
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Article Category: Review
Published Online: Sep 24, 2019
Page range: 265 - 274
Received: Feb 16, 2019
Accepted: Jun 24, 2019
DOI: https://doi.org/10.2478/raon-2019-0033
Keywords
© 2019 Vlad-Adrian Afrăsânie, Mihai Vasile Marinca, Teodora Alexa-Stratulat, Bogdan Gafton, Marius Păduraru, Anca Maria Adavidoaiei, Lucian Miron, Cristina Rusu, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1

Flow chart of the search for the eligible studies.
Flow chart of the search for the eligible studies.

Figure 2

Summary features of biomarkers in stage IV colorectal cancer EGFR = epithelial growth factor receptor; FOLFOXIRI = regimen of chemotherapy consisting of 5-fluorouracil, folinic acid, oxaliplatin and irinotecan; MMR = mismatch repair; MSI = microsatellite instability; OS = overall survival; WT = wild type
Summary features of biomarkers in stage IV colorectal cancer EGFR = epithelial growth factor receptor; FOLFOXIRI = regimen of chemotherapy consisting of 5-fluorouracil, folinic acid, oxaliplatin and irinotecan; MMR = mismatch repair; MSI = microsatellite instability; OS = overall survival; WT = wild type
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Medicine, Clinical Medicine, Internal Medicine, Haematology, Oncology, Radiology
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