A Pilot Study on Markers of Genetic Predisposition in Tuberculous Pneumonia Patients In Latgale
Published Online: Apr 07, 2019
Page range: 189 - 191
Received: Oct 29, 2018
Accepted: Mar 04, 2019
DOI: https://doi.org/10.2478/prolas-2019-0030
Keywords
© 2019 Ksenija Kramiča et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
Tuberculosis (TB) is still one of the top ten leading causes of death in the world. Compared to other Baltic and Eastern European countries, TB incidence (24.8 new cases per 100 000 people in 2017) in Latvia is relatively high. One of the regions with the highest TB incidence is Latgale (31.1 cases per 100 000 people). The aim of this pilot study was to identify markers of genetic predisposition to TB in Latgale. The study included 26 patients (16 males and 10 females) aged between 18 and 85 with bilateral TB pneumonia and without HIV infection. HLA typing was performed in