<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Wound healing is a dynamic and physiological process for restoring the normal architecture and functionality of damaged tissue. Platelet-rich plasma (PRP) is an autologous whole blood product that contains a large number of platelets in a small volume of plasma with complete set of coagulation factors, which are in physiological concentrations. PRP has haemostatic, adhesive properties and acts supraphysiologically in the process of wound healing and osteogenesis. Platelets play a very important role in the wound healing process by providing growth factors that enhance the rate and quality of wound healing by many different mechanisms. The aim of this review is to describe: the biology of platelets and their role in the wound healing process, the terminology of platelet rich products, PRP preparation, activation and concentration of PRP, as well as the use of PRP in plastic surgery.</p></abstract>

Wound healing is a dynamic and physiological process for restoring the normal architecture and functionality of damaged tissue. Platelet-rich plasma (PRP) is an autologous whole blood product that contains a large number of platelets in a small volume of plasma with complete set of coagulation factors, which are in physiological concentrations. PRP has haemostatic, adhesive properties and acts supraphysiologically in the process of wound healing and osteogenesis. Platelets play a very important role in the wound healing process by providing growth factors that enhance the rate and quality of wound healing by many different mechanisms. The aim of this review is to describe: the biology of platelets and their role in the wound healing process, the terminology of platelet rich products, PRP preparation, activation and concentration of PRP, as well as the use of PRP in plastic surgery.

Platlet-Rich Plasma – Review of Literature

University Clinic for Plastic and Reconstructive Surgery

PRILOZI

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Platlet-Rich Plasma \u2013 Review of Literature"}

Wound healing is a dynamic and physiological process for restoring the normal architecture and functionality of damaged tissue. Platelet-rich plasma (PRP) is...

Platlet-Rich Plasma – Review of Literature

Published Online: Apr 23, 2021

Page range: 127 - 139

DOI: https://doi.org/10.2478/prilozi-2021-0011

Keywords
platelet-rich plasma, wound healing, plastic surgery

© 2021 Bisera Nikolovska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Platlet-Rich Plasma – Review of Literature

Published Online: Apr 23, 2021

Page range: 127 - 139

DOI: https://doi.org/10.2478/prilozi-2021-0011

Keywordsplatelet-rich plasma, wound healing, plastic surgery

© 2021 Bisera Nikolovska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
platelet-rich plasma, wound healing, plastic surgery