[1. Fleischmann C, Scherag A, Adhikari NK, et al. Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations. Am J Respir Crit Care Med 2016; 193(3): 259–72.10.1164/rccm.201504-0781OC26414292]Search in Google Scholar
[2. Gaieski DF, Mikkelsen ME, Band RA. et al. Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. Crit Care Med 2010; 38: 1045–53.10.1097/CCM.0b013e3181cc482420048677]Open DOISearch in Google Scholar
[3. Hoenigl M, Raggam RB, Wagner J, et al. Diagnostic accuracy of soluble urokinase plasminogen activator receptor (suPAR) for prediction of bacteremia in patients with systemic inflammatory response syndrome. ClinBiochem 2013; 46: 225–9.2315929310.1016/j.clinbiochem.2012.11.00423159293]Search in Google Scholar
[4. Wildi K, Tschudin-Sutter S, Dell-Kuster S, et al. Factors associated with positive blood cultures in outpatients with suspected bacteremia. Eur J ClinMicrobiol Infect Dis 2011; 30: 1615–9.10.1007/s10096-011-1268-021503837]Search in Google Scholar
[5. Falguera M, Trujillano J, Caro S, et al. A prediction rule for estimating the risk of bacteremia in patients with community-acquired pneumonia. Clin Infect Dis 2009; 49: 409–16.10.1086/60029119555286]Search in Google Scholar
[6. Bone RC BR, Cerra FB, Dellinger RP, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992; 101: 1644–55.]Search in Google Scholar
[7. Kaukonen KM, Bailey M, Pilcher D, et al. Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med 2015; 372: 1629–1638.10.1056/NEJMoa141523625776936]Search in Google Scholar
[8. Singer M, Deutschman C, Seymour C, et al. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016; 315: 801–10.10.1001/jama.2016.0287496857426903338]Search in Google Scholar
[9. Leth RA, Forman BE, Kristensen B. Predicting bloodstream infection via systemic inflammatory response syndrome or biochemistry. J Emerg Med 2013; 44: 550–7.10.1016/j.jemermed.2012.07.0592299977522999775]Open DOISearch in Google Scholar
[10. Jones GR, Lowes JA. The systemic inflammatory response syndrome as a predictor of bacteraemia and outcome from sepsis. Q J Med 1996; 89: 515–22.10.1093/qjmed/89.7.5158759492]Search in Google Scholar
[11. Dellinger RP, Levy MM, Rhodes A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013; 41: 580–637.10.1097/CCM.0b013e31827e83af23353941]Search in Google Scholar
[12. Vincent JL, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996; 22(7): 707–710.10.1007/BF017097518844239]Search in Google Scholar
[13. Hall KK, Lyman JA. Updated review of blood culture contamination. ClinMicrobiol Rev 2006; 19(4): 788–802.10.1128/CMR.00062-05]Search in Google Scholar
[14. Richter SS, Beekmann SE, Croco JL, et al. Minimizing the workup of blood culture contaminants: implementation and evaluation of a laboratory-based algorithm. J ClinMicrobiol2002; 40: 2437–2444.10.1128/JCM.40.7.2437-2444.200212057912089259]Search in Google Scholar
[15. Wildi K, Tschudin-Sutter S, Dell-Kuster S, et al. Factors associated with positive blood cultures in outpatients with suspected bacteremia. Eur J ClinMicrobiol Infect Dis 2011; 30: 1615–9.10.1007/s10096-011-1268-021503837]Search in Google Scholar
[16. Chou HL, Han ST, Yeh CF, et al. Systemic inflammatory response syndrome is more associated with bacteremia in elderly patients with suspected sepsis in emergency departments. Medicine (Baltimore) 2016; 95(49): e5634.10.1097/MD.0000000000005634526606827930596]Search in Google Scholar
[17. Coburn B, Morris AM, Tomlinson G, et al. Does this adult patient with suspected bacteremia require blood cultures? JAMA 2012; 308: 502–11.10.1001/jama.2012.8262]Search in Google Scholar
[18. Taniguchi T, Tsuha S, Takayama Y, et al. Shaking chills and high body temperature predict bacteremia especially among elderly patients. Springer-plus 2013; 2: 624.10.1186/2193-1801-2-624384133024298435]Search in Google Scholar
[19. Gomolin IH, Aung MM, Wolf-Klein G, et al. Older is colder: temperature range and variation in older people. J Am GeriatrSoc 2005; 53: 2170–2.10.1111/j.1532-5415.2005.00500.x16398904]Search in Google Scholar
[20. Phua J, Ngerng W, See K, et al. Characteristics and outcomes of culture-negative versus culture-positive severe sepsis. Crit Care 2013; 17(5): R202.10.1186/cc12896405741624028771]Open DOISearch in Google Scholar
[21. Cretikos M. A., Bellomo R., Hillman K., et al. Respiratory rate: the neglected vital sign. Med. J. Aust2008; 188: 657–659.10.5694/j.1326-5377.2008.tb01825.x18513176]Search in Google Scholar
[22. Jaimes F, Arango C, Ruiz G et al. Predicting bacteraemia at the bedside. Clinical Infectious Diseases 2004; 38: 357–362.10.1086/38096714727205]Open DOISearch in Google Scholar
[23. Seigel TA, Cocchi MN, Salciccioli J et al. Inadequacy of temperature and white blood cell count in predicting bacteremia in patients with suspected infection. J Emerg Med 2012; 42: 254–9.10.1016/j.jemermed.2010.05.03820674238]Open DOISearch in Google Scholar
[24. Brun-Buisson C, Doyon F, Carlet J, et al. Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis. JAMA 1995; 274: 968–974.10.1001/jama.1995.03530120060042]Search in Google Scholar
[25. Vincent JL, Sakr Y, Sprung CL, et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 2006; 34: 344–353.10.1097/01.CCM.0000194725.48928.3A16424713]Open DOISearch in Google Scholar
[26. Routsi C, Pratikaki M, Sotiropoulou C, et al. Application of the sequential organ failure assessment (SOFA) score to bacteremic ICU patients. Infection 2007; 35(4): 240–4.10.1007/s15010-007-6217-617646912]Open DOISearch in Google Scholar
[27. Jansma G, Buter H, Gerritsen RT, Boerma EC. Is hemoglobin concentration affected by sepsis in the acute phase?.Crit Care 2013;17(Suppl 2): P10.10.1186/cc11948]Search in Google Scholar
[28. Tsirigotis P, Chondropoulos S, Frantzeskaki F, et al. Thrombocytopenia in critically ill patients with severe sepsis/septic shock: prognostic value and association with a distinct serum cytokine profile. J Crit Care 2016; 32: 9–15.10.1016/j.jcrc.2015.11.01026726794]Open DOISearch in Google Scholar
[29. Mosevoll KA, Skrede S, Markussen DL, et al. Inflammatory Mediator Profiles Differ in Sepsis Patients With and Without Bacteremia. Front Immunol 2018; 9: 691.10.3389/fimmu.2018.00691589750329681903]Search in Google Scholar
[30. Kim B, Choi J, Kim K, et al. Bacteremia Prediction Model for Community-acquired Pneumonia: External Validation in a Multicenter Retrospective Cohort. AcadEmerg Med 2017; 24(10): 1226–1234.10.1111/acem.1325528714287]Search in Google Scholar