<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The aim of this study was to evaluate the usability of systemic inflammatory response syndrome (SIRS) and commonly used biochemical parameters as predictors for positive blood culture in patients with sepsis. The study included 313 patients aged ≥18 years with severe sepsis and septic shock consecutively admitted in the Intensive Care Unit (ICU) of the University Clinic for Infectious Diseases in Skopje, Republic of North Macedonia. The study took place from January 1, 2011 to December 31, 2017. We recorded demographic variables, common laboratory tests, SIRS parameters, site of infection, comorbidities and Sequential Organ Failure Assessment (SOFA) score. Blood cultures were positive in 65 (20.8%) patients with sepsis. Gram-positive bacteria were isolated from 35 (53.8%) patients. From the evaluated variables in this study, only the presence of four SIRS parameters was associated with bacteremia, finding that will help to predict bacteremia and initiate early appropriate therapy in septic patients.</p></abstract>

The aim of this study was to evaluate the usability of systemic inflammatory response syndrome (SIRS) and commonly used biochemical parameters as predictors for positive blood culture in patients with sepsis. The study included 313 patients aged ≥18 years with severe sepsis and septic shock consecutively admitted in the Intensive Care Unit (ICU) of the University Clinic for Infectious Diseases in Skopje, Republic of North Macedonia. The study took place from January 1, 2011 to December 31, 2017. We recorded demographic variables, common laboratory tests, SIRS parameters, site of infection, comorbidities and Sequential Organ Failure Assessment (SOFA) score. Blood cultures were positive in 65 (20.8%) patients with sepsis. Gram-positive bacteria were isolated from 35 (53.8%) patients. From the evaluated variables in this study, only the presence of four SIRS parameters was associated with bacteremia, finding that will help to predict bacteremia and initiate early appropriate therapy in septic patients.

Association of Systemic Inflammatory Response Syndrome with Bacteremia in Patients with Sepsis

University Clinic for Infectious Diseases

University Clinic for Radiotherapy and Oncology

PRILOZI

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

The aim of this study was to evaluate the usability of systemic inflammatory response syndrome (SIRS) and commonly used biochemical parameters as predictors...

Association of Systemic Inflammatory Response Syndrome with Bacteremia in Patients with Sepsis

Published Online: Oct 11, 2019

Page range: 51 - 56

DOI: https://doi.org/10.2478/prilozi-2019-0014

Keywords
bacteremia, sepsis, severe sepsis, septic shock

© 2019 Krsto Grozdanovski et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Association of Systemic Inflammatory Response Syndrome with Bacteremia in Patients with Sepsis

Published Online: Oct 11, 2019

Page range: 51 - 56

DOI: https://doi.org/10.2478/prilozi-2019-0014

Keywordsbacteremia, sepsis, severe sepsis, septic shock

© 2019 Krsto Grozdanovski et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
bacteremia, sepsis, severe sepsis, septic shock