Design and fabrication of ¹²⁵I seeds for brachytherapy using capillary-based microfluidic technique

A new kind of ¹²⁵I seeds with a core-shell structure were synthesized by an easy assembling–disassembling coaxial capillaries microfluidic device. The dose distribution of a ¹²⁵I brachytherapy source fabricated by arranging six ¹²⁵I seeds collinearly within a cylindrical titanium capsule was simulated by modelling the source in a water phantom using Monte Carlo N-Particle Transport code. The influence of the motion and the core size of the ¹²⁵I seeds on the dose distribution was also studied in this work.