<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Theoretical grounds of integral vectors of ventricular depolarization and repolarization and their sum, i.e., the spatial ventricular gradient, have been studied. A systematic description and biophysical interpretation of these parameters are presented based on the distribution of cardiomyocyte action potential parameters in the inhomogeneous bidomain model of the myocardium. Recent medical studies have shown high efficiency and predictive value of the ventricular gradient, its constituents and related parameters, such as the angle between the con-stituents, the acceleration of repolarization, etc. Simple examples for a myocardial strip clarify the relationship between the action potential parameters and the resulting ventricular gradient. An explanation with graphic illustration is given for the very informative decartogram of repolarization acceleration. The results obtained here are useful in the modeling of vectorcardiograms for various pathological conditions of the heart ventricles and for various characteristics of the cardiomyocyte action potential, which determine its shape.</p>
</abstract>

Theoretical grounds of integral vectors of ventricular depolarization and repolarization and their sum, i.e., the spatial ventricular gradient, have been studied. A systematic description and biophysical interpretation of these parameters are presented based on the distribution of cardiomyocyte action potential parameters in the inhomogeneous bidomain model of the myocardium. Recent medical studies have shown high efficiency and predictive value of the ventricular gradient, its constituents and related parameters, such as the angle between the con-stituents, the acceleration of repolarization, etc. Simple examples for a myocardial strip clarify the relationship between the action potential parameters and the resulting ventricular gradient. An explanation with graphic illustration is given for the very informative decartogram of repolarization acceleration. The results obtained here are useful in the modeling of vectorcardiograms for various pathological conditions of the heart ventricles and for various characteristics of the cardiomyocyte action potential, which determine its shape.

Vectorcardiographic Ventricular Gradient with Constituents, and Myocardial Action Potential Parameter Distribution

Measurement Science Review

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Theoretical grounds of integral vectors of ventricular depolarization and repolarization and their sum, i.e., the spatial ventricular gradient, have been...

Vectorcardiographic Ventricular Gradient with Constituents, and Myocardial Action Potential Parameter Distribution

Published Online: Jan 21, 2022

Page range: 44 - 49

Received: Aug 14, 2021

Accepted: Nov 25, 2021

DOI: https://doi.org/10.2478/msr-2022-0005

Keywords
vectorcardiography, dipole electrocardiotopography, ventricular gradient, action potential of cardiomyocytes, bidomain model of the myocardium

© 2022 Eduard A. I. Aidu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Vectorcardiographic Ventricular Gradient with Constituents, and Myocardial Action Potential Parameter Distribution

Published Online: Jan 21, 2022

Page range: 44 - 49

Received: Aug 14, 2021

Accepted: Nov 25, 2021

DOI: https://doi.org/10.2478/msr-2022-0005

Keywordsvectorcardiography, dipole electrocardiotopography, ventricular gradient, action potential of cardiomyocytes, bidomain model of the myocardium

© 2022 Eduard A. I. Aidu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
vectorcardiography, dipole electrocardiotopography, ventricular gradient, action potential of cardiomyocytes, bidomain model of the myocardium