<abstract xmlns="http://www.w3.org/1999/xhtml">

In medicine, bismuth is used as an antimicrobial agent. In dentistry, it is used primarily to increase radiopacity in some endodontic materials. The objective is to evaluate the antimicrobial activity, cell viability, pH, solubility, film thickness, and setting time of a mineral trioxide aggregated (MTA)-types of cement with different concentrations of bismuth trioxide. Three experimental MTA-types of cement with a bismuth trioxide (Bi2O3) concentration of 15 wt%, 20 wt%, and 25 wt% were used. The antimicrobial activity test was conducted on <italic>Streptococcus mutans</italic> and <italic>Porphyromonas gingivalis</italic> strains. Cell viability was measured by the quantitative colorimetric assay using the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyltetrazolium bromide) assay on a mouse fibroblast cell line (L929). Solubility, film thickness, and setting time were performed according to ISO 6876. The lowest Bi2O3 concentrations showed the best antimicrobial activity and cell viability. pH, solubility, setting time, and film thickness did not show statistically significant differences between the different Bi2O3 concentrations tested.
</abstract>

In medicine, bismuth is used as an antimicrobial agent. In dentistry, it is used primarily to increase radiopacity in some endodontic materials. The objective is to evaluate the antimicrobial activity, cell viability, pH, solubility, film thickness, and setting time of a mineral trioxide aggregated (MTA)-types of cement with different concentrations of bismuth trioxide. Three experimental MTA-types of cement with a bismuth trioxide (Bi2O3) concentration of 15 wt%, 20 wt%, and 25 wt% were used. The antimicrobial activity test was conducted on Streptococcus mutans and Porphyromonas gingivalis strains. Cell viability was measured by the quantitative colorimetric assay using the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyltetrazolium bromide) assay on a mouse fibroblast cell line (L929). Solubility, film thickness, and setting time were performed according to ISO 6876. The lowest Bi2O3 concentrations showed the best antimicrobial activity and cell viability. pH, solubility, setting time, and film thickness did not show statistically significant differences between the different Bi2O3 concentrations tested.

Antimicrobial activity, viability, and physicochemical properties of an MTA-type cement with different concentrations of bismuth trioxide

Materials Science-Poland

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

In medicine, bismuth is used as an antimicrobial agent. In dentistry, it is used primarily to increase radiopacity in some endodontic materials. The objective...

Antimicrobial activity, viability, and physicochemical properties of an MTA-type cement with different concentrations of bismuth trioxide

Published Online: Nov 20, 2023

Page range: 339 - 353

Received: Sep 04, 2023

Accepted: Oct 02, 2023

DOI: https://doi.org/10.2478/msp-2023-0026

Keywords
MTA, bismuth trioxide, solubility, setting time, antimicrobial activity

© 2023 Miryam Martínez-Hernández et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Antimicrobial activity, viability, and physicochemical properties of an MTA-type cement with different concentrations of bismuth trioxide

Published Online: Nov 20, 2023

Page range: 339 - 353

Received: Sep 04, 2023

Accepted: Oct 02, 2023

DOI: https://doi.org/10.2478/msp-2023-0026

KeywordsMTA, bismuth trioxide, solubility, setting time, antimicrobial activity

© 2023 Miryam Martínez-Hernández et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
MTA, bismuth trioxide, solubility, setting time, antimicrobial activity