External Progesterone Supplementation During the Ovsynch Protocol Reduces the Incomplete Luteolysis in Dairy Cows Under Heat Stress

1 Hansen, P.J. (2011). Managing reproduction during heat stress in dairy cows.In C.A. Risco, P. Melendez Retamal (Eds.) Dairy production medicine, First Edition (pp. 153-164). John Wiley & Sons, Inc. https://doi.org/10.1002/9780470960554.ch13 Search in Google Scholar

2 Wolfenson, D., Roth, Z., Meidan, R. (2000). Impaired reproduction in heat - stressed cattle: basic and applied aspects. Anim Reprod Sci. (60 - 61): 535-547. https://doi.org/10.1016/S0378-4320(00)00102-0 PMid:10844222 Search in Google Scholar

3 López-Gatius, F., Santolaria, P., Martino, A., Delétang, F., De Rensis, F. (2006). The effects of GnRH treatment at the time of AI and 12 days later on reproductive performance of high producing dairy cows during the warm season in northeastern Spain. Theriogenology 65(4): 820-830. https://doi.org/10.1016/j.theriogenology.2005.07.002 PMid:16112722 Search in Google Scholar

4 Mendonça, L.G.D., Mantelo, F.M., Stevenson, J.S. (2017). Fertility of lactating dairy cows treated with gonadotropin-releasing hormone at AI, 5 days after AI, or both, during summer heat stress. Theriogenology. 91, 9-16. https://doi.org/10.1016/j.theriogenology.2016.11.032 PMid:28215691 Search in Google Scholar

5 Denicol, A.C., Lopes Jr., G., Mendonça, L.G.D., Rivera, F.A., Guagnini, F., Perez, R.V., Lima, J.R., et al. (2012). Low progesterone concentration during the development of the first follicular wave reduces pregnancy per insemination of lactating dairy cows. J Dairy Sci. 95(4): 1794-1806. https://doi.org/10.3168/jds.2011-4650 PMid:22459828 Search in Google Scholar

6 Bisinotto, R.S., Chebel, R.C., Santos, J.E.P. (2010). Follicular wave of the ovulatory follicle and notcyclic status influences fertility of dairy cows. J Dairy Sci. 93(8): 3578-3587. https://doi.org/10.3168/jds.2010-3047 PMid:20655426 Search in Google Scholar

7 Wiltbank, M.C., Pursley, J.R. (2014). The cow as an induced ovulator: timed AI after synchronization of ovulation. Theriogenology 81(1): 170-185. https://doi.org/10.1016/j.theriogenology.2013.09.017 PMid:24274420 Search in Google Scholar

8 Atanasov, B., Hostens, M., Celeska, I., Ilieska, K., Opsomer, G., Dovenski, T. (2015). Follicular dynamics following induced luteolysis and transvaginal ultrasound-guided aspiration of the largest follicle in dairy cows. Vet Arhiv. 85(3): 247-260. Search in Google Scholar

9 Wiltbank, M.C., Souza, A.H., Carvalho, P.D., Cunha, A.P., Giordano, J.O., Fricke, P.M., Baez, G.M., Diskin, M.G. (2014). Physiological and practical effects of progesterone on reproduction in dairy cattle. Animal 8 (Suppl. 1): 70-81. https://doi.org/10.1017/S1751731114000585 PMid:24703103 Search in Google Scholar

10 Pulley, S.L., Keisler, D.H., Stevenson, J.S. (2015). Concentrations of luteinizing hormone and ovulatory responses in dairy cows before timed artificial insemination. J Dairy Sci. 98(9): 6188-6201. https://doi.org/10.3168/jds.2015-9473 PMid:26142861 Search in Google Scholar

11 Stevenson, J.S. (2016). Physiological predictors of ovulation and pregnancy risk in a fixed-time artificial insemination program. J Dairy Sci. 99(12): 10077-10092. https://doi.org/10.3168/jds.2016-11247 PMid:27720155 Search in Google Scholar

12 Giordano, J.O., Wiltbank, M.C., Fricke, P.M., Bas, S., Pawlisch, R., Guenther, J.N., Nascimento, A.B. (2013). Effect of increasing GnRH and PGF2α dose during Double-Ovsynch on ovulatory response, luteal regression, and fertility of lactating dairy cows. Theriogenology 80(7): 773-783. https://doi.org/10.1016/j.theriogenology.2013.07.003 PMid:23932174 Search in Google Scholar

13 Wiltbank, M.C., Baez, G.M., Cochrane, F., Barletta, R.V., Trayford, C.R., Joseph, R.T. (2015). Effect of a second treatment with prostaglandin F2α during the Ovsynch protocol on luteolysis and pregnancy in dairy cows. J Dairy Sci. 98(12): 8644-8654. https://doi.org/10.3168/jds.2015-9353 PMid:26433418 Search in Google Scholar

14 Atanasov, B., Dovenski, T., Celeska, I., Stevenson, J. S. (2021). Luteolysis, progesterone, and pregnancy per insemination after modifying the standard 7-day Ovsynch program in Holstein-Friesian and Holstein cows. J Dairy Sci. 104(6): 7272-7282. https://doi.org/10.3168/jds.2020-19922 PMid:33773782 Search in Google Scholar

15 Ferguson, J.D., Galligan, D.T., Thomsen, N. (1994). Principal descriptors of body condition score in Holstein cows. J Dairy Sci. 77(9): 2695-2703. https://doi.org/10.3168/jds.S0022-0302(94)77212-X PMid:7814740 Search in Google Scholar

16 Stevenson, J.S., Sauls, J.A., Mendonça, L.G.D., Voelz, B.E. (2018). Dose and frequency of PGF2α administration to lactating dairy cows exposed to pre-synchronization and either five- or seven day Ovsynch protocols: ovulation, luteolysis, and pregnancy rates. J Dairy Sci. 101(10): 9575-9590. https://doi.org/10.3168/jds.2018-14653 PMid:30100501 Search in Google Scholar

17 Dovenski, T., Atanasov, B., Ilievska, K., Stojanov, B., Jasari, B. (2016). Implementation of “on-farm” method for early detection of non- pregnant cows by a single ultrasonographic examination of the ovaries on day 21 after artificial insemination. Reprod Domest Anim. 51(S2): 73. Search in Google Scholar

18 Vitali, A., Segnalini, M., Bertocchi, L., Bernabucci, U., Nardone, A., Lacetera, N. (2009). Seasonal pattern of mortality and relationships between mortality and temperature-humidity index in dairy cows. J Dairy Sci. 92(8): 3781-3790. https://doi.org/10.3168/jds.2009-2127 PMid:19620660 Search in Google Scholar

19 Bisinotto, R.S., Santos, E.P. (2011). The use of endocrine treatments to improve pregnancy rates in cattle. Reprod Fertil Dev. 24(1): 258-266. https://doi.org/10.1071/RD11916 PMid:22394967 Search in Google Scholar

20 Martins, J.P.N., Policelli, R.K., Neuder, L.M., Raphael, W., Pursley, J.R. (2011). Effects of cloprostenol sodium at final prostaglandin F2α of Ovsynch on complete luteolysis and pregnancy per artificial insemination in lactating dairy cows. J Dairy Sci. 94(6): 2815-2824. https://doi.org/10.3168/jds.2010-3652 PMid:21605751 Search in Google Scholar

21 Bisinotto, R.S., Castro, L.O., Pansani, M.B., Narciso, C.D., Martinez, N., Sinedino, L.D.P., Pinto, T.L.C., et al. (2015). Progesterone supplementation to lactating dairy cows without a corpus luteum at initiation of the Ovsynch protocol. J. Dairy Sci. 98(4): 2515-2528. https://doi.org/10.3168/jds.2014-9058 PMid:25682137 Search in Google Scholar

22 Xu, Z.Z., Burton, L.J., MacMillan, K.L. (1997). Reproductive performance of lactating dairy cows following estrus synchronization regimens with PGF2α and P4. Theriogenology 47(3): 687-701. https://doi.org/10.1016/S0093-691X(97)00027-7 PMid:16728021 Search in Google Scholar

23 Cunha, A.P., Guenther, J.N., Maroney, M.J., Giordano, J.O., Nascimento, A.B., Bas, S., Ayres, H., Wiltbank, M.C. (2008). Effects of high vs. low progesterone concentrations during Ovsynch on double ovulation rate and pregnancies per AI in high producing dairy cows. J Dairy Sci. 91 (Suppl. 1): 246. Search in Google Scholar

24 Silvia, W.J., Lewis, G.S., McCracken, J.A., Thatcher, W.W., Wilson, Jr. L. (1991). Hormonal regulation of uterine secretion of prostaglandin F2α during luteolysis in ruminants. Biol Reprod. 45(5): 655-663. https://doi.org/10.1095/biolreprod45.5.655 PMid:1756203 Search in Google Scholar

25 Souza, A.H., Silva, E.P.B., Cunha, A.P., Gumen, A., Ayres, H., Brusveen, D.J., Guenther, J.N., Wiltbank, M.C. (2011). Ultrasonographic evaluation of endometrial thickness near timed AI as a predictor of fertility in high-producing dairy cows. Theriogenology 75(4): 722-733. https://doi.org/10.1016/j.theriogenology.2010.10.013 PMid:21196031 Search in Google Scholar

26 Atanasov, B., Adamov, N., Celeska, I., Ilievska, K., Angjelovski, B., Trbogazov, Z., Davkov, F., et al. (2020). Modification of the standard 7-day Ovsynch protocol to increase the luteolytic and synchronization risks in dairy cows. Mac Vet Rev. 43(2): 161-167. https://doi.org/10.2478/macvetrev-2020-0028 Search in Google Scholar