<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Thе current study goal was to compare the results from the histopathological and immunohistochemical findings in dogs that have previously been clinically diagnosed with parvovirus infection. The Canine parvovirus enteritis (PVE) is a highly contagious disease mostly affecting dogs below six months of age. The canine parvovirus (CPV) belongs to the parvoviridae family within the feline parvovirus sub group of the genus Parvovirus. This investigation was performed on twenty dogs 2 to 12 months old with previous clinical diagnosis for PVE, and it included necropsy, histopathology, and immunohistochemistry. The necropsy findings included severe hemorrhagic enteritis and enlarged mesenteric lymph nodes as most frequent and prominent changes. The histopathological changes were also most significant in these organs in the form of villus atrophy and lymphoid depletion, respectively. These areas revealed the highest expression of CPV antigen. The histopathological and immunohistochemical methods provide strong base for a reliable CPV diagnosis.</p>
</abstract>

Thе current study goal was to compare the results from the histopathological and immunohistochemical findings in dogs that have previously been clinically diagnosed with parvovirus infection. The Canine parvovirus enteritis (PVE) is a highly contagious disease mostly affecting dogs below six months of age. The canine parvovirus (CPV) belongs to the parvoviridae family within the feline parvovirus sub group of the genus Parvovirus. This investigation was performed on twenty dogs 2 to 12 months old with previous clinical diagnosis for PVE, and it included necropsy, histopathology, and immunohistochemistry. The necropsy findings included severe hemorrhagic enteritis and enlarged mesenteric lymph nodes as most frequent and prominent changes. The histopathological changes were also most significant in these organs in the form of villus atrophy and lymphoid depletion, respectively. These areas revealed the highest expression of CPV antigen. The histopathological and immunohistochemical methods provide strong base for a reliable CPV diagnosis.

Immunohistochemical Diagnostic Characteristics of Parvovirus Infection in Dogs

Ss. Cyril and Methodius University in Skopje

Macedonian Veterinary Review

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Immunohistochemical Diagnostic Characteristics of Parvovirus Infection in Dogs"}

Thе current study goal was to compare the results from the histopathological and immunohistochemical findings in dogs that have previously been clinically...

Immunohistochemical Diagnostic Characteristics of Parvovirus Infection in Dogs

Published Online: Jul 28, 2023

Page range: 193 - 198

Received: Feb 10, 2023

Accepted: Jul 10, 2023

DOI: https://doi.org/10.2478/macvetrev-2023-0024

Keywords
diagnosis, necropsy, histopathology, immunohistochemistry, canine parvovirus

© 2023 Ivica Gjurovski et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Immunohistochemical Diagnostic Characteristics of Parvovirus Infection in Dogs

Published Online: Jul 28, 2023

Page range: 193 - 198

Received: Feb 10, 2023

Accepted: Jul 10, 2023

DOI: https://doi.org/10.2478/macvetrev-2023-0024

Keywordsdiagnosis, necropsy, histopathology, immunohistochemistry, canine parvovirus

© 2023 Ivica Gjurovski et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
diagnosis, necropsy, histopathology, immunohistochemistry, canine parvovirus