<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Myxomatous mitral valve disease (MMVD) is one of the most common heart diseases in Cavalier King Charles spaniel (CKCS) dogs. The American College of Veterinary Internal Medicine (ACVIM) uses clinical, echocardiographic, and radiographic criteria to diagnose the disease, but measurement of vertebral left atrial size (VLAS) provides a simpler assessment. The aim of this study was to determine VLAS values in MMVD cases of CKCS and to investigate their clinical significance at different MMVD stages. Eighteen CKCS dogs of both sexes, different ages and weights, and different MMVD stages (6 at B1 stage, 6 at B2 stage, and 6 at C stage) were included in the study, as well as 6 healthy CKCS as control group A. We performed clinical, radiological, and echocardiographic examinations. VHS and VLAS values were significantly higher in the MMVD group than in the control group (p&lt;0.001). VLAS showed high diagnostic accuracy in the detection of LA enlargement (area under the curve [AUC]: 0.98, cutoff ≥ 2.25, sensitivity: 88%, specificity: 100%, p&lt;0.001). We also found high positive correlations between the VLAS and other values (LA /Ao, LVIDDn, and VHS) (r=0.88, r=0.88, and r=0.86, respectively) (p&lt;0.001). It has been concluded that a VLAS value ≥2.25 can provide a meaningful diagnosis of left atrial enlargement in dogs with MMVD CKCS.</p>
</abstract>

Myxomatous mitral valve disease (MMVD) is one of the most common heart diseases in Cavalier King Charles spaniel (CKCS) dogs. The American College of Veterinary Internal Medicine (ACVIM) uses clinical, echocardiographic, and radiographic criteria to diagnose the disease, but measurement of vertebral left atrial size (VLAS) provides a simpler assessment. The aim of this study was to determine VLAS values in MMVD cases of CKCS and to investigate their clinical significance at different MMVD stages. Eighteen CKCS dogs of both sexes, different ages and weights, and different MMVD stages (6 at B1 stage, 6 at B2 stage, and 6 at C stage) were included in the study, as well as 6 healthy CKCS as control group A. We performed clinical, radiological, and echocardiographic examinations. VHS and VLAS values were significantly higher in the MMVD group than in the control group (p<0.001). VLAS showed high diagnostic accuracy in the detection of LA enlargement (area under the curve [AUC]: 0.98, cutoff ≥ 2.25, sensitivity: 88%, specificity: 100%, p<0.001). We also found high positive correlations between the VLAS and other values (LA /Ao, LVIDDn, and VHS) (r=0.88, r=0.88, and r=0.86, respectively) (p<0.001). It has been concluded that a VLAS value ≥2.25 can provide a meaningful diagnosis of left atrial enlargement in dogs with MMVD CKCS.

Radiographic Evaluation of Left Atrial Size in Cavalier King Charles Spaniel Dogs with Mitral Valve Disease

Department of Internal Medicine, Faculty of Veterinary Medicine

Macedonian Veterinary Review

This work is licensed under the Creative Commons Attribution 4.0 International License.

Myxomatous mitral valve disease (MMVD) is one of the most common heart diseases in Cavalier King Charles spaniel (CKCS) dogs. The American College of...

Radiographic Evaluation of Left Atrial Size in Cavalier King Charles Spaniel Dogs with Mitral Valve Disease

Published Online: Jul 28, 2023

Page range: 165 - 170

Received: Mar 31, 2023

Accepted: Jun 12, 2023

DOI: https://doi.org/10.2478/macvetrev-2023-0023

Keywords
left atrial size, cavalier, myxomatous mitral valve

© 2023 Gonul Remzi et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Radiographic Evaluation of Left Atrial Size in Cavalier King Charles Spaniel Dogs with Mitral Valve Disease

Published Online: Jul 28, 2023

Page range: 165 - 170

Received: Mar 31, 2023

Accepted: Jun 12, 2023

DOI: https://doi.org/10.2478/macvetrev-2023-0023

Keywordsleft atrial size, cavalier, myxomatous mitral valve

© 2023 Gonul Remzi et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
left atrial size, cavalier, myxomatous mitral valve