<abstract xmlns="http://www.w3.org/1999/xhtml">

<p><italic>Trichosomoides crassicauda</italic> (<italic>T. crassicauda</italic>) is a parasite commonly localized in the urinary bladder (UB) of laboratory and wild rats. The presence of these helminths can influence the prediction of pathological changes in the UB. Therefore, the purpose of this research was to make a comprehensive study of the features of the morphological changes in the UB wall of white laboratory rats as a result of <italic>T. crassicauda</italic> infestation. The study was performed on male rats using histological (Hematoxyline-Eosin and Alcian Blue staining) and immunohistochemical (Ki-67, Hsp70, Hsp90α, CD3 and CD20) methods. <italic>T. crassicauda</italic> was detected in both urine and UB samples. Morphological changes were observed as disruption in urothelial cell stratification and insignificant proliferative and immune responses in the UB. Increased heat shock protein levels were observed which may suggest a natural body’s resistance to this parasite.</p>
</abstract>

Trichosomoides crassicauda (T. crassicauda) is a parasite commonly localized in the urinary bladder (UB) of laboratory and wild rats. The presence of these helminths can influence the prediction of pathological changes in the UB. Therefore, the purpose of this research was to make a comprehensive study of the features of the morphological changes in the UB wall of white laboratory rats as a result of T. crassicauda infestation. The study was performed on male rats using histological (Hematoxyline-Eosin and Alcian Blue staining) and immunohistochemical (Ki-67, Hsp70, Hsp90α, CD3 and CD20) methods. T. crassicauda was detected in both urine and UB samples. Morphological changes were observed as disruption in urothelial cell stratification and insignificant proliferative and immune responses in the UB. Increased heat shock protein levels were observed which may suggest a natural body’s resistance to this parasite.

Morphological Peculiarities of Parasitic (<italic>Trichosomoides crassicauda</italic>) Infection in Rat Urinary Bladder

Macedonian Veterinary Review

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Morphological Peculiarities of Parasitic () Infection in Rat Urinary Bladder

Trichosomoides crassicauda (T. crassicauda) is a parasite commonly localized in the urinary bladder (UB) of laboratory and wild rats. The presence of these...

Morphological Peculiarities of Parasitic (Trichosomoides crassicauda) Infection in Rat Urinary Bladder

Published Online: Oct 26, 2021

Page range: 159 - 167

Received: Feb 03, 2021

Accepted: Apr 26, 2021

DOI: https://doi.org/10.2478/macvetrev-2021-0019

Keywords
nematode, parasite, rat, urinary bladder

© 2021 Vladyslav Sikora et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Morphological Peculiarities of Parasitic (Trichosomoides crassicauda) Infection in Rat Urinary Bladder

Published Online: Oct 26, 2021

Page range: 159 - 167

Received: Feb 03, 2021

Accepted: Apr 26, 2021

DOI: https://doi.org/10.2478/macvetrev-2021-0019

Keywordsnematode, parasite, rat, urinary bladder

© 2021 Vladyslav Sikora et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
nematode, parasite, rat, urinary bladder